[BBC] [Gtpb] New Bioinformatics training course announcement CSDM13

[Pedro Fernandes]

                      Course Announcement

Applications are open for:

CSDM13
"Chromosome structure determination using modeling and Hi-C data"
with Davide Baù and François Serra  (CNAG and CRG, Barcelona)

IMPORTANT DATES for this Course
    Deadline for applications: November 20th 2013
    Notification of acceptance within 72 hours of application
    Course date: November 27th to November 29th 2013

More details at the course website
http://gtpb.igc.gulbenkian.pt/bicourses/CSDM13/

*Course description*
The sequence of a genome alone does not carry enough information to  
fully understand how genomic processes are carried out in the cell  
nucleus; to achieve this, the knowledge of the three-dimensional (3D)  
architecture of a genome is necessary. Advances in genomic  
technologies and the development of new analytical methods, such as  
3C-based methods, have allowed getting insights at unprecedented  
resolution into how the genome is organized. Recently, it has been  
shown that chromatin is organized in Topologically Associating Domains  
(TADs), large interaction domains that appear to be conserved among  
different cell types.
In this course, participants will learn to use TADBit, a software for  
the analysis and 3D modeling of Topologically Associated Domains  
(TADs) and genomes. TADBit is based on a computational module of the  
Integrative Modeling Platform (IMP,  
http://www.integrativemodeling.org) that uses chromosome conformation  
capture data to determine the 3D architecture of genomic domains and  
entire genomes at unprecedented resolutions.
Participants can bring-in specific biological questions and/or their  
on data to work on during the course.

*Target Audience*
The course is oriented to experimental researchers with minimal  
computational skills, at the graduate and post-graduate levels. It is  
also suitable for bioinformatics developers at all levels. We  
anticipate that this course is attended by people with several types  
of interests in genome organization. It is likely that they may also  
aim at getting involved in generating Hi-C data for chromosome  
structure determination and that they want to model its 3D  
representation, but that does not need to be the case for all the  
participants: they may, for example, just want to explore publicly  
available data.


Pedro Fernandes
GTPB Organiser

PS. You may be interested in a recent review on the subject of this course,

"Exploring the three-dimensional organization of genomes: interpreting  
chromatin interaction data"
  Job Dekker, Marc A. Marti-Renom & Leonid A. Mirny
     Nature Reviews Genetics, 14, 390–403 (2013) doi:10.1038/nrg3454
http://www.nature.com/nrg/journal/v14/n6/full/nrg3454.html

-- 
--
Pedro Fernandes
Instituto Gulbenkian de Ciência
Apartado 14
2781-901 OEIRAS
PORTUGAL
Tel +351 21 4407912
http://gtpb.igc.gulbenkian.pt




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