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<div class="column"><p><p><font face="Gill Sans MT" size="4"><b>Research context</b></font></p><p><font face="Gill Sans MT" size="4">This job opening has been created in the context of an FWO research grant entitled: “Complementary use of ribosome profiling and positional proteomics for mapping the translation initiation and nascent protein modification landscape in human cell lines”. The PhD student will be working in a multi-disciplinary environment within a collaboration of three different research groups: the Proteomics and CompOmics groups of the VIB Department of Medical Protein Research, and the BioBix-Lab of Bioinformatics and Computational Genomics.</font></p><p><font face="Gill Sans MT" size="4"><b>Job description</b></font></p><p><font face="Gill Sans MT" size="4">High-throughput applications such as next-generation sequencing are frequently applied in modern biological and medical research. Recent technology advancements enable protein translation measurement on the RNA level by massive sequencing of ribosome-captured messenger RNA footprints. This work will focus on the intersection between the state-of-the-art fields of high-throughput RNA sequencing and high-throughput positional proteomics analysis. Specific tasks include preprocessing, statistical validation and genome-wide visualization of sequencing and proteomics data, and development of a toolbox integrating experimental sequencing data and search space optimization for mass spectrometry based proteomics research.</font></p><p><font face="Gill Sans MT" size="4">A start date of 1 March 2013 is proposed but this is flexible depending on the availability of the successful candidate.</font></p><p><font face="Gill Sans MT" size="4"><b>Profile</b></font></p><p><font face="Gill Sans MT" size="4">The successful candidate will have obtained or will obtain a Master’s degree in a relevant field (life sciences, informatics, statistics, biology, (bio-) engineering) and will have a keen interest/knowledge in bioinformatics and data processing. Experience in computational genomics or proteomics is considered an advantage. Experience with programming languages (notably Perl, Java, C++) and/or relational database systems (e.g., MySQL, SQLite) is also considered an advantage.</font></p><p><font face="Gill Sans MT" size="4"><b>Contact</b></font></p><p><font face="Gill Sans MT" size="4">Please submit a cover letter, a full c.v., and a list of at least two contact persons (with name, email, address, phone number) for letters of reference to <a href="mailto:petra.vandamme@vib-ugent.be">petra.vandamme@vib-ugent.be</a>, or: Prof. Dr. Petra Van Damme, VIB Department of Medical Protein Research , A. Baertsoenkaai 3, B-9000 Gent, BELGIUM.</font></p><p><font face="Gill Sans MT" size="4"><b>Links</b></font></p><p><font face="Gill Sans MT" size="4"><a href="http://www.vib.be/en/research/scientists/Pages/kris-gevaert-Lab.aspx">http://www.vib.be/en/research/scientists/Pages/kris-gevaert-Lab.aspx</a> </font></p><p><font face="Gill Sans MT" size="4"><a href="http://www.biobix.be">http://www.biobix.be</a></font></p><p><font face="Gill Sans MT" size="4"><a href="http://www.compomics.com">http://www.compomics.com</a> </font></p></p></div></div><div class="layoutArea"><div class="column">
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