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    <h3
      style="margin-top:12.0pt;margin-right:0cm;margin-bottom:0cm;margin-left:
0cm;margin-bottom:.0001pt;text-indent:0cm;mso-list:none;tab-stops:35.45pt"><span
        style="font-size:12.0pt;mso-bidi-font-family:Arial;mso-ansi-language:

        EN-GB" lang="EN-GB"><big>Small molecules, gene products and
          their interaction </big><o:p></o:p></span></h3>
    <h3
      style="margin-top:12.0pt;margin-right:0cm;margin-bottom:0cm;margin-left:
0cm;margin-bottom:.0001pt;text-indent:0cm;mso-list:none;tab-stops:35.45pt"><span
        style="font-size:12.0pt;mso-bidi-font-family:Arial" lang="EN-US">EBI

        Roadshow, Pathway-Network course and DiXa Training Course<o:p></o:p></span></h3>
    <h3
      style="margin-top:12.0pt;margin-right:0cm;margin-bottom:0cm;margin-left:
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        style="font-size:12.0pt;mso-bidi-font-family:Arial;mso-ansi-language:

        EN-GB" lang="EN-GB"><o:p>&nbsp;</o:p></span></h3>
    <h3
      style="margin-top:12.0pt;margin-right:0cm;margin-bottom:0cm;margin-left:
0cm;margin-bottom:.0001pt;text-indent:0cm;mso-list:none;tab-stops:35.45pt"><span
        style="font-size:12.0pt;mso-bidi-font-family:Arial;mso-ansi-language:

        EN-GB" lang="EN-GB">General information<o:p></o:p></span></h3>
    <p class="mijnlistindent"
      style="margin-left:92.15pt;text-indent:-92.15pt"><span
style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-ansi-language:EN-GB"
        lang="EN-GB">Date:<span style="mso-tab-count:2">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

        </span>July 1- 5, 2013 <o:p></o:p></span></p>
    <p class="mijnlistindent"
      style="margin-left:92.15pt;text-indent:-92.15pt"><span
style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-ansi-language:EN-GB"
        lang="EN-GB">Location:<span style="mso-tab-count:1">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

        </span>Maastricht, the Netherlands<o:p></o:p></span></p>
    <p class="mijnlistindent"
      style="margin-left:92.15pt;text-indent:-92.15pt"><span
style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-ansi-language:EN-GB"
        lang="EN-GB">Website:<span style="mso-tab-count:1">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

        </span></span><span class="MsoHyperlink"><span
style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;color:#0070C0;mso-ansi-language:EN-GB"
          lang="EN-GB"><a class="moz-txt-link-freetext"
href="http://www.nbic.nl/education/course-overview/pages3/1/coursedetails/small-molecules-gene-products-and-their-interaction/">http://www.nbic.nl/education/course-overview/pages3/1/coursedetails/small-molecules-gene-products-and-their-interaction/</a></span></span><span
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          style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;
          mso-ansi-language:EN-GB" lang="EN-GB"><o:p></o:p></span></span></p>
    <p class="mijnlistindent"
      style="margin-left:92.15pt;text-indent:-92.15pt"><span
style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-ansi-language:EN-GB"
        lang="EN-GB">Organisers:<span style="mso-tab-count:1">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
        </span>Chris Evelo (Maastricht University), Egon Willighagen
        (Maastricht University), Tom Hancocks (EMBL-EBI), Vera Matser
        (EMBL-EBI &amp; DiXa), Celia van Gelder (NBIC)<o:p></o:p></span></p>
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style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-ansi-language:EN-GB"
        lang="EN-GB">Registration:<span style="mso-tab-count:1"> </span><span
          style="mso-spacerun:yes">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span></span><span
style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;color:#0070C0"
        lang="EN-US"><a class="moz-txt-link-freetext"
          href="http://www.nbic.nl/education/nbic-phd-school/enrolment/">http://www.nbic.nl/education/nbic-phd-school/enrolment/</a></span><span
style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-ansi-language:EN-GB"
        lang="EN-GB"><o:p></o:p></span></p>
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      style="margin-left:92.15pt;text-indent:-92.15pt"><span
style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-ansi-language:NL">Contact:<span
          style="mso-tab-count:1">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span>Celia van
        Gelder (NBIC), </span><span
style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;color:#0070C0;mso-ansi-language:EN-GB"
        lang="EN-GB"><a href="mailto:education@nbic.nl"><span
            style="color:#0070C0; mso-ansi-language:NL" lang="NL">education@nbic.nl</span></a><br>
      </span><span
style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;color:#0070C0;mso-ansi-language:NL"><o:p></o:p></span></p>
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      style="margin-left:92.15pt;text-indent:-92.15pt"><span
style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;color:#0070C0;mso-ansi-language:NL"><o:p>&nbsp;</o:p></span></p>
    <h3 style="mso-list:l0 level3 lfo1"><span style="font-size:12.0pt;
mso-bidi-font-family:Arial;mso-ansi-language:EN-GB;mso-bidi-font-weight:normal"
        lang="EN-GB">Course description<o:p></o:p></span></h3>
    <h3
      style="margin-left:0cm;text-indent:0cm;mso-list:none;tab-stops:35.45pt"><span
        style="font-size:12.0pt;mso-bidi-font-family:Arial;mso-ansi-language:

        EN-GB;font-weight:normal" lang="EN-GB">This five day course
        introduces various databases and data analysis tools to get
        grips on the big data in the life sciences. <o:p></o:p></span></h3>
    <h3 style="mso-list:l0 level3 lfo1"><span style="font-size:12.0pt;
mso-bidi-font-family:Arial;mso-ansi-language:EN-GB;font-weight:normal"
        lang="EN-GB">The course consists of two parts: <o:p></o:p></span></h3>
    <h3
      style="margin-left:0cm;text-indent:0cm;mso-list:none;tab-stops:35.45pt"><span
        style="font-size:12.0pt;mso-bidi-font-family:Arial;mso-ansi-language:

        EN-GB;font-weight:normal" lang="EN-GB">Part 1 (day 1-3)
        introduces the advanced uses of the gene and genomes databases,
        small molecule resources, the protein sequence databases, and
        interaction and pathway databases at EBI (a.o. UniPROT, ENSEMBL,
        CHEMBL, IntAct and Reactome). <br>
        This first part is an EBI<span style="mso-spacerun:yes">&nbsp; </span>Roadshow

        hosted by UM &amp; NBIC. <span style="mso-spacerun:yes">&nbsp;</span><o:p></o:p></span></h3>
    <h3
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        style="font-size:12.0pt;mso-bidi-font-family:Arial;mso-ansi-language:

        EN-GB;font-weight:normal" lang="EN-GB">The second part (day 4-5)
        focuses on real data analysis using pathway and network
        approaches with links to the databases covered in first part. <br>
        Tools that will be used include WikiPathways, PathVisio and
        Cytoscape. Covered aspects include pathway creation, data
        preparation for analysis, pathway analysis. network analysis and
        network extension using target information. <br>
        This second part is provided by the department of
        Bioinformatics-BiGCaT at Maastricht University in collaboration
        with the DiXa FP7 project (<a class="moz-txt-link-abbreviated"
          href="http://www.dixa-fp7.eu">www.dixa-fp7.eu</a>) on systems
        biology approaches in toxicogenomics. <br>
        The DiXa project will provide examples about (re)use and
        (re)analysis of large genomics datasets.</span><span
        style="font-size:12.0pt;mso-bidi-font-family:
Arial;mso-ansi-language:EN-GB;font-weight:normal;mso-bidi-font-weight:bold"
        lang="EN-GB"><o:p></o:p></span></h3>
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        style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;
        mso-ansi-language:EN-GB" lang="EN-GB"><b>Teachers</b><br>
        Denise Carvalho-Silva, Louisa Bellis, Sandra Orchard, Chris
        Evelo, Martina Kutmon, Christoper Hardt, Stathis Kanterakis,
        Anwesha Dutta, Egon Willighagen.<br
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style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-ansi-language:EN-GB"
          lang="EN-GB">Target audience<br>
        </span></b><span
style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-ansi-language:EN-GB"
        lang="EN-GB">This course is intended for researchers in Life
        Sciences, Bioinformatics and Systems Biology, Pharmacology,
        Toxicology.<o:p></o:p></span></p>
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        mso-ansi-language:EN-GB" lang="EN-GB"><o:p>&nbsp;</o:p></span></p>
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style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-ansi-language:EN-GB"
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        style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;
        mso-ansi-language:EN-GB" lang="EN-GB"><o:p> <br>
          See </o:p></span><a
        href="http://www.nbic.nl/uploads/media/Programme_Maastricht.pdf">http://www.nbic.nl/uploads/media/Programme_Maastricht.pdf</a></p>
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    <pre class="moz-signature" cols="72">-- 
Dr. Celia W.G. van Gelder
Coordinator Education CMBI
Projectleader Education NBIC
tel. +31-(0)24-3666120
e-mail: <a class="moz-txt-link-abbreviated" href="mailto:C.vanGelder@cmbi.ru.nl">C.vanGelder@cmbi.ru.nl</a> 
websites: <a class="moz-txt-link-abbreviated" href="http://www.cmbi.ru.nl">www.cmbi.ru.nl</a>, <a class="moz-txt-link-abbreviated" href="http://www.nbic.nl">www.nbic.nl</a>

Postal address:
CMBI 260
Radboud University Nijmegen-Medical Centre /NCMLS
PO Box 9101, 6500 HB Nijmegen
The Netherlands </pre>
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