<div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div><span style="color:rgb(51,51,51);font-family:Georgia,serif;font-size:22.5pt;line-height:24pt">Postdoc research position LC-MS/MS data preprocessing
and statistical analysis (216165)</span><br></div><div>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:19.5pt"><span lang="NL" style="font-size:12pt;font-family:"Times New Roman",serif"> </span></p>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:19.5pt"><span lang="NL" style="font-size:18pt;font-family:Georgia,serif;color:rgb(51,51,51)">Organisation</span></p>
<p class="MsoNormal" style="margin-bottom:12pt;line-height:13.5pt"><span style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)">The Faculty of Mathematics and Natural Sciences harbours a kaleidoscope of
disciplines and research strengths. Our programmes in research and education range
from nanomaterials and biomachinery to astronomy, from mathematics to pharmacy,
from neurosciences to computer science, and from molecular and evolutionary
biology to marine biology.<br>
Our researchers pursue fundamental key questions while collaborating with
partners from industry, the medical world and other realms of society.
Frontline research groups explore new fields such as synthetic biologyand
sustainable energy use.</span></p>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:19.5pt"><span style="font-size:18pt;font-family:Georgia,serif;color:rgb(51,51,51)">Job description</span></p>
<p class="MsoNormal" style="margin-bottom:12pt;line-height:13.5pt"><span style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)">Development of single-stage LC-MS/MS data preprocessing and statistical
analysis approaches for risk assessment of mycotoxin exposure through dietary
intake in Qatar.</span></p>
<p class="MsoNormal" style="margin-bottom:12pt;line-height:13.5pt"><span style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)">This postdoctoral position is embedded within the interdisciplinary
research groups of Analytical Biochemistry/Department of Pharmacy1 at the
Faculty of Mathematics and Natural Science of the University of Groningen
(RUG).</span></p>
<p class="MsoNormal" style="margin-bottom:12pt;line-height:13.5pt"><span style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)">Mycotoxins are the most ubiquitous carcinogenic contaminant in the human
food supply leading to adverse consequences on human population such as
hepatocellular carcinoma. Mycotoxin concentrations are regularly measured in
food but their impact on human population health remain unclear. The aim of
this project is to perform risk assessment of mycotoxin exposure of Qatar
population through dietary intake in collaboration with scientists of the Anti
Doping Lab Qatar2.<br>
In the research project the postdoctoral scientist is expected i) to develop
and implement novel single stage, data dependent and data independent
LC-MS(/MS) data pre-processing workflows based on Threshold Avoiding
Proteomics3 pipeline and other open source tool such as OpenMS4, XCMS5 and
mzMine6, and ii) statistical analysis of obtained molecular profile for
mycotoxin exposure in pilot animal study and in human population and iii)
perform risk assessment of human population in Qatar based on obtained data.<br>
The successful candidate will strongly benefit from working in a highly
interdisciplinary research team composed of clinical researchers, analytical
chemists, bioinformaticians and statisticians. The Analytical Biochemistry group
has an excellent scientific infrastructure and track record in proteomics,
proteogenomics and computational Mass Spectrometry1.</span></p>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:19.5pt"><span style="font-size:18pt;font-family:Georgia,serif;color:rgb(51,51,51)">Qualifications</span></p>
<p class="MsoNormal" style="margin-bottom:12pt;line-height:13.5pt"><span style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)">The candidate should have a strong background in mathematics and statistics
and should have strong experience in C++, Matlab and/or R programming.
Experience with data analysis in mass spectrometry would be a significant
advantage. The candidate should be able to work in an interdisciplinary and
multinational research team and have good communication skills.</span></p>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:19.5pt"><span style="font-size:18pt;font-family:Georgia,serif;color:rgb(51,51,51)">Conditions of employment</span></p>
<p class="MsoNormal" style="margin-bottom:12pt;line-height:13.5pt"><span style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)">The University of Groningen offers a salary that is determined in
accordance with the rules as set out in the collective labour agreement for the
Dutch Universities (CAO) and has a range between € 3,044 and € 3,997 (scale 10
Dutch Universities) gross per month depending on qualifications and experience
based on a fulltime position. The position is temporary for one year. After a
positive successful evaluation in the first year, the contract will be extended
by 1.5 year.<br>
The University of Groningen offers an excellent research infrastructure and
training programme to develop research skills of the successful candidate.</span></p>
<p class="MsoNormal" style="margin-bottom:12pt;line-height:13.5pt"><span style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)">Link references:<br>
1 </span><span lang="NL" style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)"><a href="http://www.biomac.nl/" target="_blank"><span lang="EN-US" style="color:rgb(119,45,107)">http://www.biomac.nl</span></a></span><span style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)"> <br>
2 </span><span lang="NL" style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)"><a href="http://adlqatar.net/" target="_blank"><span lang="EN-US" style="color:rgb(119,45,107)">http://adlqatar.net/</span></a></span><span style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)"> <br>
3 Suits F, Hoekman B, Rosenling T, Bischoff R, Horvatovich P.,
Threshold-avoiding proteomics pipeline, Anal Chem. 2011, 15;83(20):7786-94.<br>
4 Bertsch A, Gröpl C, Reinert K, Kohlbacher O., OpenMS and TOPP: open source
software for LC-MS data analysis, Methods Mol Biol. 2011;696:353-67.<br>
5 Mahieu NG, Genenbacher JL, Patti GJ., A roadmap for the XCMS family of
software solutions in metabolomics, Curr Opin Chem Biol., 2016, 30:87-93.<br>
6 Pluskal T, Castillo S, Villar-Briones A, Oresic M., MZmine 2: modular
framework for processing, visualizing, and analyzing mass spectrometry-based
molecular profile data, BMC Bioinformatics. 2010, 11:395.</span></p>
<p class="MsoNormal" style="margin-bottom:12pt;line-height:13.5pt"><span style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)">Additional information and sending in of applications<br>
Applications with curriculum vitae and the names of three former or present
supervisors who can be contacted as references should be sent until 14 July /
before 15 July 2016 Dutch local time by means of the application form (click on
the link below).</span></p>
<p class="MsoNormal" style="margin-bottom:12pt;line-height:13.5pt"><span style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)">Unsolicited marketing is not appreciated.</span></p>
<p class="MsoNormal" style="margin-bottom:7.5pt;line-height:19.5pt"><span style="font-size:18pt;font-family:Georgia,serif;color:rgb(51,51,51)">Information</span></p>
<p class="MsoNormal" style="margin-bottom:12pt;line-height:13.5pt"><span style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)">For information you can contact:</span></p>
<p class="MsoNormal" style="margin-bottom:3.75pt;margin-left:0cm"><span style="line-height:13.5pt;font-size:10pt;font-family:Symbol;color:rgb(51,51,51)">·</span><span style="color:rgb(51,51,51)"><font face="Times New Roman" size="1"> </font></span><span style="line-height:13.5pt;font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)">Prof. P.L. Horvatovich, +31 50 3633341, </span><span lang="NL" style="line-height:13.5pt;font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)"><a href="mailto:p.l.horvatovich@rug.nl" target="_blank"><span lang="EN-US" style="color:rgb(119,45,107)">p.l.horvatovich@rug.nl</span></a></span><span style="line-height:13.5pt;font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)"></span></p>
<p class="MsoNormal" style="margin-bottom:12pt;line-height:13.5pt"><span style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)">(please do not use for applications)</span></p>
<p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:13.5pt"><span lang="NL" style="font-size:8.5pt;font-family:Verdana,sans-serif;color:rgb(51,51,51)"><b><span style="color:rgb(119,45,107);border:1pt solid rgb(3,130,211);padding:0cm"><a href="http://www.rug.nl/about-us/work-with-us/job-opportunities/overview?reply=00347-02S0004ZFP" target="_blank">Apply</a></span></b></span></p><p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:13.5pt"><span style="color:rgb(51,51,51);font-family:Verdana,sans-serif;font-size:8.5pt;line-height:13.5pt">or direct link:</span><br></p><p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:13.5pt"><a href="http://www.rug.nl/about-us/work-with-us/job-opportunities/overview?reply=00347-02S0004ZFP" target="_blank" style="line-height:normal"><font color="#333333" face="Verdana, sans-serif"><span style="font-size:11.3333px;line-height:18px">http://www.rug.nl/about-us/work-with-us/job-opportunities/overview?reply=00347-02S0004ZFP</span></font></a><br></p>
<p class="MsoNormal"><span lang="NL"> </span></p></div><div><div><br></div>-- <br><div data-smartmail="gmail_signature"><div dir="ltr"><div><br></div><div>Peter Horvatovich</div><div>Associate Professor</div><div><br></div><div>University of Groningen</div><div>Faculty of Mathematics and Natural Sciences</div><div>Department of Pharmacy</div><div>Analytical Biochemistry</div><div><br></div><div>Building 3226, Room 6.9</div><div>Antonius Deusinglaan 1</div><div>9713 AV Groningen</div><div>Internal Zip Code XB20</div><div>P.O. Box 196</div><div>9700 AD Groningen</div><div>The Netherlands</div><div><br></div><div>Telephone: +31-(0)50-363 3341</div><div>Fax: +31 (0)50 363 7582</div><div>Mobile: +31 (0)6 2459 7203</div><div>Email: <a href="mailto:p.l.horvatovich@rug.nl" target="_blank">p.l.horvatovich@rug.nl</a></div><div>Homepage: <a href="http://www.biomac.nl" target="_blank">www.biomac.nl</a></div></div></div></div></div></div>
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