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</o:shapelayout></xml><![endif]--></head><body lang=NL link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal style='margin-bottom:12.0pt'><b><span lang=EN-US style='font-size:12.0pt;font-family:"Helvetica","sans-serif"'>BioSB RNA- seq data analysis course (6<sup>th</sup> edition)</span></b><span lang=EN-US style='font-size:10.0pt;font-family:"Helvetica","sans-serif"'><br><br><u>Date:</u> 26-28 September, 2016<br><u>Location:</u> Leiden, the Netherlands<br><u>Course coordinators:</u> Peter-Bram ‘t Hoen (LUMC), Jan Oosting (LUMC), Celia van Gelder (BioSB, <a href="mailto:education@biosb.nl"><span style='color:windowtext'>education@biosb.nl</span></a> )<br><u>Course website:</u> <a href="http://biosb.nl/education/course-portfolio/rna-seq/"><span style='color:windowtext'>http://biosb.nl/education/course-portfolio/rna-seq/</span></a> . <br><u>Registration:</u> <a href="http://biosb.nl/education/course-portfolio/rna-seq/enrollment-rnaseq-2016/"><span style='color:windowtext'>http://biosb.nl/education/course-portfolio/rna-seq/enrollment-rnaseq-2016/</span></a> <br><u>More information:</u> <a href="mailto:education@biosb.nl"><span style='color:windowtext'>education@biosb.nl</span></a> <o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><b><span lang=EN-US style='font-size:10.0pt;font-family:"Helvetica","sans-serif"'>Course description<br></span></b><span lang=EN-US style='font-size:10.0pt;font-family:"Helvetica","sans-serif"'>BioSB and partner LUMC are organizing a 3-day course on RNA-seq. This is an expert course for people with experience in NGS and a follow-up course on the general NGS data analysis course (coordinator Jeroen Laros, LUMC). The course will consist of seminars and hands-on command line, Galaxy and R practicals and will focus on data preprocessing, quality control, alignment, visualization and statistics for differential transcript expression. Examples will be taken from human and mouse studies. The course does not cover prokaryotic RNA profiling nor plant- and metagenomics aspects. <o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><b><span lang=EN-US style='font-size:10.0pt;font-family:"Helvetica","sans-serif"'>Course topics <br></span></b><span lang=EN-US style='font-size:10.0pt;font-family:"Helvetica","sans-serif"'>RNA-seq experimental approaches <br>Alignment and de novo assembly <br>Statistics for differential gene expression <br>eQTL analysis and allele specific expression <br>Variant calling and RNA editing <br>Small RNA profiling <br>Software for RNA-seq data analysis<o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><b><span lang=EN-US style='font-size:10.0pt;font-family:"Helvetica","sans-serif"'>Programme<br></span></b><span lang=EN-US style='font-size:10.0pt;font-family:"Helvetica","sans-serif"'>The programme can be found here: <a href="http://biosb.nl/wp-content/uploads/2016/07/RNAseq_program_2016_v4.pdf"><span style='color:windowtext'>http://biosb.nl/wp-content/uploads/2016/07/RNAseq_program_2016_v4.pdf</span></a> <b><o:p></o:p></b></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><b><span lang=EN-US style='font-size:10.0pt;font-family:"Helvetica","sans-serif"'>Target audience<br></span></b><span lang=EN-US style='font-size:10.0pt;font-family:"Helvetica","sans-serif"'>Participants for the RNA-seq course should preferably have participated in the general NGS course or otherwise have demonstrated hands-on experience with NGS data analysis. The course is aimed at PhD students and post-docs, but scientific programmers and data analysts with a background in biology and bioinformatics may also attend. <strong><span style='font-family:"Helvetica","sans-serif"'>The practicals are mostly in R. We require that participants have at least basic knowledge of R and experience in running R scripts.</span></strong> Registrations will be handled on a first-come-first-served basis but experience and motivation will be reviewed. Seats have been reserved for participants in the FP7-funded projects <a href="http://rd-connect.eu/"><span style='color:windowtext'>RD-Connect</span></a>, <a href="http://www.rd-neuromics.eu/"><span style='color:windowtext'>Neuromics</span></a>, <a href="http://www.eurenomics.eu/"><span style='color:windowtext'>Eurenomics</span></a> and <a href="https://www.bbmri.nl/"><span style='color:windowtext'>BBMRI-NL</span></a>.<o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span lang=EN-US style='font-size:10.0pt;font-family:"Helvetica","sans-serif"'><br><b>BioSB Course Programme<br></b></span><span lang=EN-US>This course is part of the <a href="http://biosb.nl/education/course-portfolio-2/"><span style='color:windowtext'>Course Portfolio</span></a> of BioSB, the Netherlands Bioinformatics and Systems Biology research school, which offers training and education for in bioinformatics and systems biology.<br>More information about BioSB can be found at <a href="http://www.biosb.nl"><span style='color:windowtext'>www.biosb.nl</span></a>.<br></span><span lang=EN-US style='font-size:10.0pt;font-family:"Helvetica","sans-serif"'><br><b>More information<br></b>For more information about the course you can contact Celia van Gelder at <u><a href="mailto:education@biosb.nl"><span style='color:windowtext'>education@biosb.nl</span></a></u>. </span><span lang=EN-US style='font-size:12.0pt;font-family:"Times New Roman","serif"'><o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US><o:p> </o:p></span></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:10.5pt;font-family:"Arial","sans-serif"'>Dr. Celia W.G. van Gelder<o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span lang=EN-US style='font-size:10.5pt;font-family:"Arial","sans-serif"'>Programme Manager Learning DTL/ELIXIR-NL Training<br>Education Manager BioSB<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:10.5pt;font-family:"Arial","sans-serif"'>tel. +31613375327<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:10.5pt;font-family:"Arial","sans-serif"'>e-mail: <a href="mailto:celia.van.gelder@dtls.nl">celia.van.gelder@dtls.nl</a><o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:10.5pt;font-family:"Arial","sans-serif"'>websites: <a href="http://www.dtls.nl/"><span style='color:windowtext'>www.dtls.nl</span></a>, <a href="http://www.biosb.nl/"><span style='color:windowtext'>www.biosb.nl</span></a><o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:10.5pt;font-family:"Arial","sans-serif"'>skype: celia.van.gelder<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:10.5pt;font-family:"Arial","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:10.5pt;font-family:"Arial","sans-serif"'>Postal address:<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";background:white'>DTL<br>PO Box 19245</span><span style='font-size:10.0pt;font-family:"Arial","sans-serif"'><br><span style='background:white'>3501 DE Utrecht</span></span><o:p></o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal><o:p> </o:p></p></div></body></html>