<div dir="ltr"><span id="gmail-docs-internal-guid-93360426-0b60-e048-5a33-647911cc54c0"><font face="arial, helvetica, sans-serif"><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;font-weight:700;vertical-align:baseline;white-space:pre-wrap"><font size="4">BioSB Course Quantitative and Predictive Modelling</font></span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;font-weight:700;vertical-align:baseline;white-space:pre-wrap">Date:  26-30 June, 2017</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;font-weight:700;vertical-align:baseline;white-space:pre-wrap">Location: Wageningen</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;font-weight:700;vertical-align:baseline;white-space:pre-wrap">Course Coordinators: Natal van Riel (TUE) &amp; Jaap Molenaar (WUR)</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap"> </span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap">Website: </span><a href="http://biosb.nl/education/course-portfolio-2/course-quantitative-and-predictive-modelling/" style="text-decoration-line:none"><span style="background-color:transparent;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">http://biosb.nl/education/course-portfolio-2/course-quantitative-and-predictive-modelling/</span></a><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap"> </span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap">Registration:  </span><a href="http://biosb.nl/education/course-portfolio-2/course-quantitative-and-predictive-modelling/enrollment-quantitative-and-predictive-modelling-course/" style="text-decoration-line:none"><span style="background-color:transparent;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">http://biosb.nl/education/course-portfolio-2/course-quantitative-and-predictive-modelling/enrollment-quantitative-and-predictive-modelling-course/</span></a><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap"> </span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap"> </span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap">Please note that this course is free of charge for PhDs who are or become a</span><a href="http://biosb.nl/about/members/biosb-membership-information/" style="text-decoration-line:none"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap"> </span><span style="background-color:transparent;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">member of the  BioSB research school</span></a><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap">.</span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;font-weight:700;vertical-align:baseline;white-space:pre-wrap">Description</span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap">On June 26-30 2017,  BioSB organises the second edition of the course Quantitative and Predictive Modelling (QPM). In this course the participants learn how to describe the dynamic behaviour of biological systems and to integrate experimental data. Concepts of modelling in terms of differential equations are introduced via a great variety of case studies taken from diverse practices. The course offers a math refresher to help those participants who are not (yet) involved in modelling on a daily basis. The emphasis is on providing an introduction into modelling approaches rather than an in-depth treatment of a few techniques and aims as such at a broad audience. The course is a mixture of theory sessions and computer practicals. During the practicals most of the time Matlab will be used. Participants not acquainted with Matlab will get an introduction. The course has to be completed with assignments in the form of practical exercises as homework afterwards.</span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;font-weight:700;vertical-align:baseline;white-space:pre-wrap">Target audience and learning objectives</span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap">This course is primarily targeted at academic researchers such as PhD students and Postdocs in Life Sciences, Bioinformatics, Systems Biology or Biomedical Engineering. Participants from the private sector are also welcome. Participants are expected to have some experience in modelling with differential equations. </span></p><br><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:15pt"><span style="vertical-align:baseline;white-space:pre-wrap"><font color="#000000">The students will be provided with a theoretical basis, a variety of methods and a computational hands-on experience to handle differential equation modelling, parameter estimation and uncertainty analysis. In the course the students will learn:</font></span></p><ul style="margin-top:0pt;margin-bottom:0pt"><li dir="ltr" style="list-style-type:disc;vertical-align:baseline;margin-left:30pt"><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="vertical-align:baseline;white-space:pre-wrap"><font color="#000000">How to set-up a dynamic model to represent biological networks using different interaction mechanisms</font></span></p></li><li dir="ltr" style="list-style-type:disc;vertical-align:baseline;margin-left:30pt"><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="vertical-align:baseline;white-space:pre-wrap"><font color="#000000">To implement, simulate and analyse dynamic network models in different software tools</font></span></p></li><li dir="ltr" style="list-style-type:disc;vertical-align:baseline;margin-left:30pt"><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="vertical-align:baseline;white-space:pre-wrap"><font color="#000000">To understand the common ground and the differences for applications in metabolic, regulatory, signalling, population and multi-scale biological processes</font></span></p></li><li dir="ltr" style="list-style-type:disc;vertical-align:baseline;margin-left:30pt"><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:15pt"><span style="vertical-align:baseline;white-space:pre-wrap"><font color="#000000">To integrate experimental data in modelling, estimate model parameters and assess the accuracy of parameter estimates and model predictions</font></span></p></li></ul><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap">This course is part of the</span><a href="http://biosb.nl/education/course-portfolio-2/" style="text-decoration-line:none"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap"> </span><span style="background-color:transparent;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">Education Programme of BioSB</span></a><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap">, the Netherlands Bioinformatics and Systems Biology Research School, which offers training and education for in bioinformatics and systems biology.</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap"><br></span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap">More information about BioSB can be found at </span><a href="http://www.biosb.nl/" style="text-decoration-line:none"><span style="background-color:transparent;text-decoration-line:underline;vertical-align:baseline;white-space:pre-wrap">www.biosb.nl</span></a><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap">. </span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap"> </span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap">Beste regards,</span></p><p dir="ltr" style="line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap"> </span></p><span style="color:rgb(0,0,0);background-color:transparent;vertical-align:baseline;white-space:pre-wrap">Femke Francissen</span></font></span><br clear="all"><div><div class="gmail_signature"><div dir="ltr"><div><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div style="word-wrap:break-word"><font face="Arial Unicode MS" color="#484848" style="color:rgb(0,0,0);font-family:calibri,sans-serif;font-size:14px"><div><span style="font-size:12px"><b><div style="font-family:&quot;trebuchet ms&quot;,sans-serif;font-size:small;display:inline">​</div></b></span><b style="font-size:12px"><div style="font-family:&quot;trebuchet ms&quot;,sans-serif;font-size:small;display:inline">​</div></b></div></font><div style="color:rgb(0,0,0);font-family:calibri,sans-serif;word-wrap:break-word"><font face="Arial Unicode MS" color="#484848"><div><span style="font-size:12px"><b>Femke Francissen</b></span></div><div style="font-size:14px"><span style="font-size:12px">Community manager BioSB</span></div><div style="font-size:14px"><span style="font-size:12px"><br></span></div><div style="font-size:14px"><span style="font-size:12px">BioSB Research School</span><span style="font-size:12px"><br></span></div><div style="font-size:14px"><div><span style="font-size:12px">Visiting address: </span><span style="font-size:12px">Geert Grooteplein 28, route 260, </span><span style="font-size:12px">6525 GA Nijmegen</span></div><div style="font-size:12.8px"><span style="font-size:12px">Postal address: P.O. box 9101, route 260, </span><span style="font-size:12px">6500 HB Nijmegen</span></div></div><div style="font-size:14px"><br></div></font></div><div style="color:rgb(0,0,0);font-family:calibri,sans-serif;font-size:14px"><span style="color:rgb(72,72,72);font-family:&quot;arial unicode ms&quot;;font-size:12px">E-mail:</span><span style="color:rgb(72,72,72);font-family:&quot;arial unicode ms&quot;;font-size:12px"> </span><a href="mailto:femke.francissen@biosb.nl" style="font-family:&quot;arial unicode ms&quot;;font-size:12px;color:rgb(17,85,204)" target="_blank">femke.francissen@biosb.nl</a><span style="color:rgb(72,72,72);font-family:&quot;arial unicode ms&quot;;font-size:12px"> </span></div><div style="color:rgb(0,0,0);font-family:calibri,sans-serif;word-wrap:break-word"><font face="Arial Unicode MS" color="#484848"><div style="font-size:14px"><span style="font-size:12px">Mobile: +31 6 17 90 4888</span></div><div style="font-size:14px"><span style="font-size:12px">Skype: femke.francissen</span><br></div><div style="font-size:14px"><span style="font-size:12px">Website: </span><span style="font-size:12px"><font color="#800080"><a href="http://www.biosb.nl/" target="_blank">www.biosb.nl</a></font></span><span style="font-size:12px"><br></span></div></font></div><div><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:small;word-wrap:break-word"><font style="color:rgb(0,0,0);font-family:calibri,sans-serif;font-size:14px"><span style="font-size:12px">LinkedIn <a href="http://nl.linkedin.com/in/femkefrancissen" style="color:rgb(17,85,204)" target="_blank">link</a></span></font></div><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:small;word-wrap:break-word"><br></div><div style="word-wrap:break-word"><img src="http://www.dtls.nl/wp-content/uploads/2014/09/BioSB_logo_full_250x226.jpg" width="96" height="85"><br></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div>
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