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</o:shapelayout></xml><![endif]--></head><body lang=EN-GB link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span lang=NL><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><b><span lang=EN-US style='font-size:13.5pt;font-family:"Arial",sans-serif;color:black'>BioSB Course Quantitative and Predictive Modelling</span></b><span lang=EN-US style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-family:"Arial",sans-serif'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><b><span lang=NL style='font-family:"Arial",sans-serif;color:black'>Date: 26-30 June, 2017</span></b><span lang=NL style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><b><span lang=NL style='font-family:"Arial",sans-serif;color:black'>Location: Wageningen</span></b><span lang=NL style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><b><span lang=NL style='font-family:"Arial",sans-serif;color:black'>Course Coordinators: Natal van Riel (TUE) & Jaap Molenaar (WUR)</span></b><span lang=NL style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span lang=NL style='font-family:"Arial",sans-serif;color:black'>Website: </span><span lang=NL style='font-family:"Arial",sans-serif'><a href="http://biosb.nl/education/course-portfolio-2/course-quantitative-and-predictive-modelling/">http://biosb.nl/education/course-portfolio-2/course-quantitative-and-predictive-modelling/</a><span style='color:black'> </span><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span lang=NL style='font-family:"Arial",sans-serif;color:black'>Registration: </span><span lang=NL style='font-family:"Arial",sans-serif'><a href="http://biosb.nl/education/course-portfolio-2/course-quantitative-and-predictive-modelling/enrollment-quantitative-and-predictive-modelling-course/">http://biosb.nl/education/course-portfolio-2/course-quantitative-and-predictive-modelling/enrollment-quantitative-and-predictive-modelling-course/</a><span style='color:black'> </span><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span lang=NL style='font-family:"Arial",sans-serif;color:black'>Please note that this course is free of charge for PhDs who are or become a</span><span lang=NL style='font-family:"Arial",sans-serif'><a href="http://biosb.nl/about/members/biosb-membership-information/"><span style='color:black'> </span>member of the BioSB research school</a><span style='color:black'>.</span><o:p></o:p></span></p><p class=MsoNormal><span lang=NL style='font-family:"Arial",sans-serif'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><b><span lang=NL style='font-family:"Arial",sans-serif;color:black'>Description</span></b><span lang=NL style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p class=MsoNormal><span lang=NL style='font-family:"Arial",sans-serif'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span lang=NL style='font-family:"Arial",sans-serif;color:black'>On June 26-30 2017, BioSB organises the second edition of the course Quantitative and Predictive Modelling (QPM). In this course the participants learn how to describe the dynamic behaviour of biological systems and to integrate experimental data. Concepts of modelling in terms of differential equations are introduced via a great variety of case studies taken from diverse practices. The course offers a math refresher to help those participants who are not (yet) involved in modelling on a daily basis. The emphasis is on providing an introduction into modelling approaches rather than an in-depth treatment of a few techniques and aims as such at a broad audience. The course is a mixture of theory sessions and computer practicals. During the practicals most of the time Matlab will be used. Participants not acquainted with Matlab will get an introduction. The course has to be completed with assignments in the form of practical exercises as homework afterwards.</span><span lang=NL style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p class=MsoNormal><span lang=NL style='font-family:"Arial",sans-serif'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><b><span lang=NL style='font-family:"Arial",sans-serif;color:black'>Target audience and learning objectives</span></b><span lang=NL style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p class=MsoNormal><span lang=NL style='font-family:"Arial",sans-serif'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span lang=NL style='font-family:"Arial",sans-serif;color:black'>This course is primarily targeted at academic researchers such as PhD students and Postdocs in Life Sciences, Bioinformatics, Systems Biology or Biomedical Engineering. Participants from the private sector are also welcome. Participants are expected to have some experience in modelling with differential equations. </span><span lang=NL style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p class=MsoNormal><span lang=NL style='font-family:"Arial",sans-serif'><o:p> </o:p></span></p><p style='mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:15.0pt;margin-left:0cm'><span lang=NL style='font-family:"Arial",sans-serif;color:black'>The students will be provided with a theoretical basis, a variety of methods and a computational hands-on experience to handle differential equation modelling, parameter estimation and uncertainty analysis. In the course the students will learn:</span><span lang=NL style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p style='mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:0cm;margin-left:66.0pt;margin-bottom:.0001pt;text-indent:-18.0pt;mso-list:l0 level1 lfo2;vertical-align:baseline'><![if !supportLists]><span lang=NL style='font-size:10.0pt;font-family:Symbol'><span style='mso-list:Ignore'>·<span style='font:7.0pt "Times New Roman"'> </span></span></span><![endif]><span lang=NL style='font-family:"Arial",sans-serif;color:black'>How to set-up a dynamic model to represent biological networks using different interaction mechanisms</span><span lang=NL style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p style='mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:0cm;margin-left:66.0pt;margin-bottom:.0001pt;text-indent:-18.0pt;mso-list:l0 level1 lfo2;vertical-align:baseline'><![if !supportLists]><span lang=NL style='font-size:10.0pt;font-family:Symbol'><span style='mso-list:Ignore'>·<span style='font:7.0pt "Times New Roman"'> </span></span></span><![endif]><span lang=NL style='font-family:"Arial",sans-serif;color:black'>To implement, simulate and analyse dynamic network models in different software tools</span><span lang=NL style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p style='mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:0cm;margin-left:66.0pt;margin-bottom:.0001pt;text-indent:-18.0pt;mso-list:l0 level1 lfo2;vertical-align:baseline'><![if !supportLists]><span lang=NL style='font-size:10.0pt;font-family:Symbol'><span style='mso-list:Ignore'>·<span style='font:7.0pt "Times New Roman"'> </span></span></span><![endif]><span lang=NL style='font-family:"Arial",sans-serif;color:black'>To understand the common ground and the differences for applications in metabolic, regulatory, signalling, population and multi-scale biological processes</span><span lang=NL style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p style='mso-margin-top-alt:0cm;margin-right:0cm;margin-bottom:15.0pt;margin-left:66.0pt;text-indent:-18.0pt;mso-list:l0 level1 lfo2;vertical-align:baseline'><![if !supportLists]><span lang=NL style='font-size:10.0pt;font-family:Symbol'><span style='mso-list:Ignore'>·<span style='font:7.0pt "Times New Roman"'> </span></span></span><![endif]><span lang=NL style='font-family:"Arial",sans-serif;color:black'>To integrate experimental data in modelling, estimate model parameters and assess the accuracy of parameter estimates and model predictions</span><span lang=NL style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span lang=NL style='font-family:"Arial",sans-serif;color:black'>This course is part of the</span><span lang=NL style='font-family:"Arial",sans-serif'><a href="http://biosb.nl/education/course-portfolio-2/"><span style='color:black'> </span>Education Programme of BioSB</a><span style='color:black'>, the Netherlands Bioinformatics and Systems Biology Research School, which offers training and education for in bioinformatics and systems biology.</span><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span lang=NL style='font-family:"Arial",sans-serif'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span lang=NL style='font-family:"Arial",sans-serif;color:black'>More information about BioSB can be found at </span><span lang=NL style='font-family:"Arial",sans-serif'><a href="http://www.biosb.nl/">www.biosb.nl</a><span style='color:black'>. </span><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span lang=NL style='font-family:"Arial",sans-serif;color:black'>Beste regards,</span><span lang=NL style='font-family:"Arial",sans-serif'><o:p></o:p></span></p><p class=MsoNormal><span lang=NL style='font-family:"Arial",sans-serif;color:black'>Femke Francissen</span><span lang=NL><br clear=all><o:p></o:p></span></p><div><div><div><div><div><div><div><div><div><div><div><div><div><div><div><div><div><p class=MsoNormal><b><span lang=NL style='font-family:"Arial",sans-serif;color:black'></span></b><b><span lang=NL style='font-family:"Trebuchet MS",sans-serif;color:black'><o:p></o:p></span></b></p></div><div><p class=MsoNormal><b><span lang=NL style='font-family:"Arial",sans-serif;color:black'></span></b><b><span lang=NL style='font-family:"Trebuchet MS",sans-serif;color:black'><o:p></o:p></span></b></p></div></div><div><div><p class=MsoNormal><b><span lang=NL style='font-size:9.0pt;font-family:"Arial Unicode MS",serif;color:#484848'>Femke Francissen</span></b><span lang=NL style='font-family:"Arial Unicode MS",serif;color:#484848'><o:p></o:p></span></p></div><div><p class=MsoNormal><span lang=NL style='font-size:9.0pt;font-family:"Arial Unicode MS",serif;color:#484848'>Community manager BioSB</span><span lang=NL style='font-size:10.5pt;font-family:"Arial Unicode MS",serif;color:#484848'><o:p></o:p></span></p></div><div><p class=MsoNormal><span lang=NL style='font-size:10.5pt;font-family:"Arial Unicode MS",serif;color:#484848'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span lang=NL style='font-size:9.0pt;font-family:"Arial Unicode MS",serif;color:#484848'>BioSB Research School</span><span lang=NL style='font-size:10.5pt;font-family:"Arial Unicode MS",serif;color:#484848'><o:p></o:p></span></p></div><div><div><p class=MsoNormal><span lang=NL style='font-size:9.0pt;font-family:"Arial Unicode MS",serif;color:#484848'>Visiting address: Geert Grooteplein 28, route 260, 6525 GA Nijmegen</span><span lang=NL style='font-size:10.5pt;font-family:"Arial Unicode MS",serif;color:#484848'><o:p></o:p></span></p></div><div><p class=MsoNormal><span lang=NL style='font-size:9.0pt;font-family:"Arial Unicode MS",serif;color:#484848'>Postal address: P.O. box 9101, route 260, 6500 HB Nijmegen</span><span lang=NL style='font-size:9.5pt;font-family:"Arial Unicode MS",serif;color:#484848'><o:p></o:p></span></p></div></div><div><p class=MsoNormal><span lang=NL style='font-size:10.5pt;font-family:"Arial Unicode MS",serif;color:#484848'><o:p> </o:p></span></p></div></div><div><p class=MsoNormal><span lang=NL style='font-size:9.0pt;font-family:"Arial Unicode MS",serif;color:#484848'>E-mail: </span><span lang=NL style='font-size:10.5pt;font-family:"Calibri",sans-serif;color:black'><a href="mailto:femke.francissen@biosb.nl" target="_blank"><span style='font-size:9.0pt;font-family:"Arial Unicode MS",serif;color:#1155CC'>femke.francissen@biosb.nl</span></a></span><span lang=NL style='font-size:9.0pt;font-family:"Arial Unicode MS",serif;color:#484848'> </span><span lang=NL style='font-size:10.5pt;font-family:"Calibri",sans-serif;color:black'><o:p></o:p></span></p></div><div><div><p class=MsoNormal><span lang=NL style='font-size:9.0pt;font-family:"Arial Unicode MS",serif;color:#484848'>Mobile: +31 6 17 90 4888</span><span lang=NL style='font-size:10.5pt;font-family:"Arial Unicode MS",serif;color:#484848'><o:p></o:p></span></p></div><div><p class=MsoNormal><span lang=NL style='font-size:9.0pt;font-family:"Arial Unicode MS",serif;color:#484848'>Skype: femke.francissen</span><span lang=NL style='font-size:10.5pt;font-family:"Arial Unicode MS",serif;color:#484848'><o:p></o:p></span></p></div><div><p class=MsoNormal><span lang=NL style='font-size:9.0pt;font-family:"Arial Unicode MS",serif;color:#484848'>Website: </span><span lang=NL style='font-size:9.0pt;font-family:"Arial Unicode MS",serif;color:purple'><a href="http://www.biosb.nl/" target="_blank">www.biosb.nl</a></span><span lang=NL style='font-size:10.5pt;font-family:"Arial Unicode MS",serif;color:#484848'><o:p></o:p></span></p></div></div><div><div><p class=MsoNormal><span lang=NL style='font-size:9.0pt;font-family:"Calibri",sans-serif;color:black'>LinkedIn <a href="http://nl.linkedin.com/in/femkefrancissen" target="_blank"><span style='color:#1155CC'>link</span></a></span><span lang=NL style='font-family:"Arial",sans-serif;color:#222222'><o:p></o:p></span></p></div><div><p class=MsoNormal><span lang=NL style='font-family:"Arial",sans-serif;color:#222222'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span lang=NL><img border=0 width=96 height=85 style='width:1.0in;height:.8854in' id="_x0000_i1025" src="http://www.dtls.nl/wp-content/uploads/2014/09/BioSB_logo_full_250x226.jpg"><o:p></o:p></span></p></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></body></html>