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</o:shapelayout></xml><![endif]--></head><body lang=EN-GB link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span style='mso-fareast-language:EN-US'><o:p> </o:p></span></p><p class=MsoNormal><o:p> </o:p></p><div><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>COURSE ANNOUNCEMENT</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:9.5pt'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>Please circulate this email to those who might be interested</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:12.0pt'>(apologies if you have already received </span><span style='font-size:9.5pt'>this announcement</span><span style='font-size:12.0pt'>)</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:9.5pt'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>ELIXIR-IIB, in collaboration with University of<b> </b>Salerno, Italy,</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>is pleased to announce the upcoming training course on <b>"</b>Best practices for RNA-Seq data analysis<b>"</b>.</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:9.5pt'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:9.5pt'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>IMPORTANT DATES:</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>Course date: <b> 27-29 September 2017</b></span><span style='font-size:9.5pt'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>Deadline for applications: <b> 11 September 2017<br><br></b>Selection will start on July 20th and those with an adequate profile will be accepted immediately<b>, </b></span><span style='font-size:9.5pt'>until we reach 2<b>5</b> participants.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:9.5pt'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'><br>VENUE: Campus di Fisciano, University of Salerno, Via Giovanni Paolo II n. 132, 84084 Fisciano (SA), Italy.</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:9.5pt'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'><br>Full details at: <a href="https://elixir-iib-training.github.io/website/2017/09/27/RNA-seq-Salerno.html" target="_blank">https://elixir-iib-training.github.io/website/2017/09/27/RNA-seq-Salerno.html</a></span><span style='font-size:9.5pt'><o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:9.5pt'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>COURSE DESCRIPTION:</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>The aim of this course is to get a deeper understanding of RNA-Seq experiments, providing a theoretical introduction to the data processing steps, together with practical sessions illustrating the use of the most popular data analysis tools. Starting from the raw sequenced data coming from different phenotypical samples (e.g disease vs healthy control samples), genes which are differentially expressed between the two conditions are determine. </span><span style='font-size:9.5pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:9.5pt'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:9.5pt'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>COURSE OBJECTIVES</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>Students will gain an understanding of:</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>- experimental design</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:10.0pt'>- quality control</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>- theoretical principles of RNA-Seq data analysis process</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:10.0pt'>- how to identify differentially regulated genes</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>- how to identify alternative splicing events</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:10.0pt'>- how to identify gene fusion events</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>- multiple testing correction</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:10.0pt'>- biological interpretation of RNA-seq data</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:9.5pt'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:9.5pt'><br></span><span style='font-size:10.0pt'>Should you have any question, do not hesitate to contact the ELIXIR-IIB Training Team (<a href="mailto:elixir.ita.training@gmail.com" target="_blank">elixir.ita.training@gmail.com</a>) and/or the local organiser Dr. Anna Marabotti (<a href="mailto:amarabotti@unisa.it" target="_blank">amarabotti@unisa.it</a>).</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:9.5pt'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>Thank you for your interest,</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:9.5pt'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>the Organisers and the ELIXIR Training Team</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>Anna Marabotti (ELIXIR Training Team and University of Salerno, Italy)</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>Loredana Le Pera (ELIXIR Training Team and IIT, Italy)</span><span style='font-size:9.5pt'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='font-size:10.0pt'>Allegra Via (ELIXIR Training Coordinator, CNR-IBPM, Italy)</span><span style='font-size:9.5pt'><o:p></o:p></span></p></div></div></body></html>