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<p class="MsoNormal"><span lang="EN-US">The Clinical Epidemiology and Systems Medicine group at the UMC Mainz invites applications for a PhD position in Computational Systems Medicine:<o:p></o:p></span></p>
<p class="MsoNormal"><b><span lang="EN-US"><o:p> </o:p></span></b></p>
<p class="MsoNormal"><b><span lang="EN-US">PhD Candidate (m/f/d) in Computational Systems Medicine</span></b><span lang="EN-US"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">Topic: Multi-omics data integration for studying complex cardiovascular diseases and their associated comorbidities in large human cohort studies<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:8.55pt;margin-right:0cm;margin-bottom:8.55pt;margin-left:0cm">
<span lang="EN-US">Employer: University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany<o:p></o:p></span></p>
<p class="MsoNormal"><b><span lang="EN-US">Your tasks:</span></b><span lang="EN-US"><o:p></o:p></span></p>
<ul style="margin-top:0cm" type="disc">
<li class="MsoNormal" style="mso-list:l1 level1 lfo1"><span lang="EN-US">Investigation of molecular processes and markers associated with complex cardiovascular diseases (e.g. heart failure), their heterogeneity, comorbidities, and molecular progression paths
based on repeatedly sampled disease-specific human cohort studies<o:p></o:p></span></li><li class="MsoNormal" style="mso-list:l1 level1 lfo1"><span lang="EN-US">Multi-dimensional and pathway-integrating analysis of multifaceted data (proteomics, metabolomics/lipidomics, transcriptomics, genomics, phenotypic/clinical) using state-of-the-art and
newly developed algorithms<o:p></o:p></span></li><li class="MsoNormal" style="mso-list:l1 level1 lfo1"><span lang="EN-US">Detection and comparison of disease subtypes for the development of personalized medicine in prevention, prognosis, and treatment<o:p></o:p></span></li></ul>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span lang="EN-US">Your profile:<o:p></o:p></span></b></p>
<ul style="margin-top:0cm" type="disc">
<li class="MsoNormal" style="mso-list:l2 level1 lfo2"><span lang="EN-US">Master degree in Computational Biology, Bioinformatics, Systems Biology, Biomathematics, Biostatistics, Epidemiology, Biomedical engineering or a related area<o:p></o:p></span></li><li class="MsoNormal" style="mso-list:l2 level1 lfo2"><span lang="EN-US">Strong interests in human biomedicine (cardiovascular diseases, diabetes, obesity) and multi-dimensional data analysis<o:p></o:p></span></li><li class="MsoNormal" style="mso-list:l2 level1 lfo2"><span lang="EN-US">Programming experience in R, python, or similar programming languages<o:p></o:p></span></li><li class="MsoNormal" style="mso-list:l2 level1 lfo2"><span lang="EN-US">Sound statistical knowledge and experience in handling bioinformatics databases and tools<o:p></o:p></span></li><li class="MsoNormal" style="mso-list:l2 level1 lfo2"><span lang="EN-US">Good communication skills and fluency in English<o:p></o:p></span></li><li class="MsoNormal" style="mso-list:l2 level1 lfo2"><span lang="EN-US">Structured and independent work attitude<o:p></o:p></span></li></ul>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span lang="EN-US">We offer:<o:p></o:p></span></b></p>
<ul style="margin-top:0cm" type="disc">
<li class="MsoNormal" style="mso-list:l0 level1 lfo3"><span lang="EN-US">An interesting research project at the forefront of computational biomedicine related to cardiometabolic diseases.<o:p></o:p></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo3"><span lang="EN-US">Access to several large and deeply phenotyped human cohort studies with high level of standardization and extensive multi-omics datasets<o:p></o:p></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo3"><span lang="EN-US">A professional and cooperative work environment in a highly interdisciplinary research team<o:p></o:p></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo3"><span lang="EN-US">A three year employment with salary according to the German public service salary scale TV-L E13, 65%
<o:p></o:p></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo3"><span lang="EN" style="font-family:"Times New Roman","serif";color:black;mso-fareast-language:NL">A stimulating scientific environment with excellent facilities for professional and personal development</span><span lang="EN-US"><o:p></o:p></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo3"><span lang="EN-US">Opportunities for child care (limited places available)<o:p></o:p></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo3"><span lang="EN-US">Job ticket for public transport<o:p></o:p></span></li></ul>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">For further information please contact Dr. rer. nat. Michael Lenz (<a href="mailto:mlenz@uni-mainz.de"><span class="InternetLink">mlenz@uni-mainz.de</span></a>) or Univ.-Prof. Dr. med. Philipp Wild (<a href="mailto:philipp.wild@unimedizin-mainz.de"><span class="InternetLink">philipp.wild@unimedizin-mainz.de</span></a>).<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span lang="EN-US">Did we catch your interest?<o:p></o:p></span></b></p>
<p class="MsoNormal"><span lang="EN-US">Please submit your application, including motivation letter, CV, recommendation letters, and copies of your diploma(s) and transcripts (high-school, bachelor, master) by e-mail to
<a href="mailto:mlenz@uni-mainz.de">mlenz@uni-mainz.de</a>.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:windowtext"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:windowtext"><o:p> </o:p></span></p>
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