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<p class="MsoNormal" style="margin-bottom:10.0pt;text-align:justify"><span style="font-size:12.0pt">Dear all,<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;text-align:justify"><span style="font-size:12.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;text-align:justify"><span style="font-size:12.0pt">SCK CEN and UHasselt are looking for candidates for a PhD project with the title: “Integromics - Towards integration of big biomolecular data to enable systems
biology”<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;text-align:justify"><span style="font-size:12.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;text-align:justify"><b><span style="font-size:12.0pt">Description</span></b><o:p></o:p></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;text-align:justify"><span style="font-size:12.0pt">The last decades, development of high-throughput technologies such as next-generation sequencing, microarrays and mass spectrometry has led to a paradigm shift
in biology and life sciences. Where previously one biomolecule (for example, a gene, or a protein) was studied as a single entity, these experimental techniques allow to study a set of biomolecules (for example, the genome or the proteome) in one go and in
a limited amount of time. While, at first,<span style="color:black"> experiments were analyzed independently from each other, combining information of several experimental techniques, and correlating them with environmental and/or clinical parameters, is,
nowadays, of great interest. As a consequence, <b>novel statistical and computational methodologies for the analysis of multi-omics datasets have to be developed</b>, allowing a multi-dimensional view on complex biological processes.</span></span><o:p></o:p></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;text-align:justify"><span style="font-size:12.0pt">In this PhD project, we aim at the development of computational methods for the analysis of multi-omics datasets, that are commonly generated by the three
<b>biology units of SCK•CEN</b>, which will improve the understanding and valorization of the data, and which will keep the biology units up to date with current developments in biology and bioinformatics.</span><o:p></o:p></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;line-height:115%"><span style="font-size:12.0pt;line-height:115%"> </span><o:p></o:p></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;line-height:11.25pt"><b><span style="font-size:10.0pt;font-family:"Verdana",sans-serif">Profile and diploma</span></b><o:p></o:p></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;line-height:11.25pt"><span style="font-size:10.0pt;font-family:"Verdana",sans-serif">As a doctorate researcher you will join the dynamic bioinformatics team at
</span><span style="font-size:12.0pt">SCK CEN and </span><span style="font-size:10.0pt;font-family:"Verdana",sans-serif">CenStat (UHasselt). A successful candidate should have :</span><o:p></o:p></p>
<ul style="margin-top:0in" type="disc">
<li class="MsoNormal" style="margin-bottom:10.0pt;line-height:11.25pt;mso-list:l0 level1 lfo1">
<span style="font-size:10.0pt;font-family:"Verdana",sans-serif">A master degree in biostatistics/applied statistics/bioinformatics/statistical bioinformatics.</span><o:p></o:p></li><li class="MsoNormal" style="margin-bottom:10.0pt;line-height:11.25pt;mso-list:l0 level1 lfo1">
<span style="font-size:10.0pt;font-family:"Verdana",sans-serif">You are acquainted with statistical methodologies and had exposure to computer programming in SAS/R/Winbugs/Python.
</span><o:p></o:p></li><li class="MsoNormal" style="margin-bottom:10.0pt;line-height:11.25pt;mso-list:l0 level1 lfo1">
<span style="font-size:10.0pt;font-family:"Verdana",sans-serif">You can work independently and within a team.</span><o:p></o:p></li><li class="MsoNormal" style="margin-bottom:10.0pt;line-height:11.25pt;mso-list:l0 level1 lfo1">
<span style="font-size:10.0pt;font-family:"Verdana",sans-serif">You have excellent communication skills.</span><o:p></o:p></li><li class="MsoNormal" style="margin-bottom:10.0pt;line-height:11.25pt;mso-list:l0 level1 lfo1">
<span style="font-size:10.0pt;font-family:"Verdana",sans-serif">You are interested to develop new methodology from both theoretical and applied aspects.</span><o:p></o:p></li><li class="MsoNormal" style="margin-bottom:10.0pt;line-height:11.25pt;mso-list:l0 level1 lfo1">
<span style="font-size:10.0pt;font-family:"Verdana",sans-serif">You enjoy working in a multidisciplinary and multicultural environment.
</span><o:p></o:p></li><li class="MsoNormal" style="margin-bottom:10.0pt;line-height:11.25pt;mso-list:l0 level1 lfo1">
<span style="font-size:10.0pt;font-family:"Verdana",sans-serif">You are willing to closely collaborate with biologists/biostatisticians.</span><o:p></o:p></li><li class="MsoNormal" style="margin-bottom:10.0pt;line-height:11.25pt;mso-list:l0 level1 lfo1">
<span style="font-size:10.0pt;font-family:"Verdana",sans-serif">You speak and write English fluently.
</span><o:p></o:p></li><li class="MsoNormal" style="margin-bottom:10.0pt;line-height:11.25pt;mso-list:l0 level1 lfo1">
<span style="font-size:10.0pt;font-family:"Verdana",sans-serif">You have work experience with at least two different “omics” platforms.</span><o:p></o:p></li></ul>
<p class="MsoNormal" style="margin-bottom:10.0pt;line-height:115%"><o:p> </o:p></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;line-height:115%"><b><span style="font-size:12.0pt;line-height:115%">For more information contact:</span></b><o:p></o:p></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;line-height:115%"><span style="font-size:12.0pt;line-height:115%">Dr. Claesen Jürgen (SCK-CEN), </span><a href="https://academy.sckcen.be/en/Mailform?contactid=b22040b5-cf18-496f-a82a-3bcbfd815f49" target="_blank"><span style="font-size:12.0pt;line-height:115%;color:#1155CC">jclaesen@sckcen.be</span></a><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:12.0pt">Prof. Shkedy Ziv (Hasselt University), </span><a href="https://academy.sckcen.be/en/Mailform?contactid=51ae7733-8006-4347-b211-9a4a1af42e4a" target="_blank"><span style="font-size:12.0pt;color:#1155CC">ziv.shkedy@uhasselt.be</span></a><o:p></o:p></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;line-height:115%"> <o:p></o:p></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;line-height:115%">Link to the project in
<span style="font-size:12.0pt;line-height:115%">SCK-CEN: </span> <a href="https://academy.sckcen.be/en/Your_thesis_internship/AllTopics/Integromics----Towards-integration-of-big-biomolecular-data-to-enable-systems-biology-2619" target="_blank"><span style="color:blue">https://academy.sckcen.be/en/Your_thesis_internship/AllTopics/Integromics----Towards-integration-of-big-biomolecular-data-to-enable-systems-biology-2619</span></a><o:p></o:p></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;line-height:115%"><o:p> </o:p></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;line-height:115%">Kind Regards,<o:p></o:p></p>
<p class="MsoNormal" style="margin-bottom:10.0pt;line-height:115%">Jürgen<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
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