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<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">Dear all,<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">We are looking for a 2-year computational postdoc in a</span><span style="font-size:10.5pt;font-family:Helvetica"> flagship collaboration between the TU Delft, the Erasmus
MC, and the Holland Proton Therapy Center</span><span style="font-size:10.5pt;font-family:Helvetica">
<span lang="EN-US">under the Convergence for Health and Technology initiative.<o:p></o:p></span></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">The project aims to model single-cell heterogeneity in response to proton therapy in head and neck cancer patient biopsies.</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">
</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">The computational postdoc at the TU Delft will work alongside a fellow experimental postdoc at Erasmus MC to: (1) characterize (un)treated tumor samples at the single-cell level using
optogenetic imaging, photoselection, and single-cell RNA sequencing; (2) model single-cell and subclonal response to treatment based on transcriptomic profiles and functional imaging features, including cell dynamics and morphology; (3) identify and interpret
biomarker signatures associated with resistance to proton therapy. <o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">The successful candidate should have a background in computer science or related, and experience in bioinformatics.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">T</span><span style="font-size:10.5pt;font-family:Helvetica">here is
</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">ample opportunity for</span><span style="font-size:10.5pt;font-family:Helvetica"> innovation and development of new ideas</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">
on fundamental algorithmic and statistical learning topics, in connection with this and other projects ongoing in the lab</span><span style="font-size:10.5pt;font-family:Helvetica">.</span><span style="font-size:10.5pt;font-family:Helvetica">
<span lang="EN-US">The postdoc will be primarily affiliated with the Gonçalves lab in the Department of Intelligent Systems at the TU Delft, with a secondary appointment in the Chien lab at Erasmus MC, and will be embedded in a larger network of 24 postdocs
funded by the Convergence initiative. </span></span><span style="font-size:10.5pt;font-family:Helvetica">The
</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">successful
</span><span style="font-size:10.5pt;font-family:Helvetica">candidate will work in a highly multidisciplinary environment, and interact with a diverse group of faculty in
</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">c</span><span style="font-size:10.5pt;font-family:Helvetica">omputer
</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">s</span><span style="font-size:10.5pt;font-family:Helvetica">cience,
</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">p</span><span style="font-size:10.5pt;font-family:Helvetica">attern
</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">r</span><span style="font-size:10.5pt;font-family:Helvetica">ecognition</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica"> and machine learning</span><span style="font-size:10.5pt;font-family:Helvetica">,
</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">b</span><span style="font-size:10.5pt;font-family:Helvetica">ioinformatics,
</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">b</span><span style="font-size:10.5pt;font-family:Helvetica">iomedical
</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">science,
</span><span style="font-size:10.5pt;font-family:Helvetica">and </span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">m</span><span style="font-size:10.5pt;font-family:Helvetica">olecular
</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">b</span><span style="font-size:10.5pt;font-family:Helvetica">iology. Th</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">is</span><span style="font-size:10.5pt;font-family:Helvetica">
project will also enable</span><span style="font-size:10.5pt;font-family:Helvetica">
<span lang="EN-US">access to</span></span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">
</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">and collaboration with
</span><span style="font-size:10.5pt;font-family:Helvetica">other leading </span>
<span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">research scientists and
</span><span style="font-size:10.5pt;font-family:Helvetica">laboratories </span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">in the Netherlands</span><span style="font-size:10.5pt;font-family:Helvetica">,
</span><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">including</span><span style="font-size:10.5pt;font-family:Helvetica"> the Oncode Institute.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.5pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">See some of what we are currently working on at
<a href="http://joanagoncalves.org/people.html">http://joanagoncalves.org/people.html</a>.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">If you believe that you are a great fit, we would like to hear from you!<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">For more information please contact me (<a href="mailto:joana.goncalves@tudelft.nl">joana.goncalves@tudelft.nl</a>), or apply directly at
<a href="https://convergence.healthandtechnology.nl/square/position/37">https://convergence.healthandtechnology.nl/square/position/37</a>.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica">Applications sent before July 18, 2020 will be given priority.</span><span lang="EN-US"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:10.5pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.5pt;font-family:Helvetica">Please, share this information with potential candidates.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.5pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="PT" style="font-size:10.5pt;font-family:Helvetica">Kind regards,<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="PT" style="font-size:10.5pt;font-family:Helvetica">Joana<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="PT" style="font-size:10.5pt;font-family:Helvetica"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:9.0pt;font-family:"Calibri Light",sans-serif;color:black;mso-fareast-language:EN-GB">--<o:p></o:p></span></p>
<p class="MsoNormal"><b><span lang="EN-US" style="font-size:9.0pt;font-family:"Calibri Light",sans-serif;color:black;mso-fareast-language:EN-GB">Joana Gonçalves<o:p></o:p></span></b></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:9.0pt;font-family:"Calibri Light",sans-serif;color:black;mso-fareast-language:EN-GB">Assistant Professor<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:9.0pt;font-family:"Calibri Light",sans-serif;color:black;mso-fareast-language:EN-GB"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span lang="EN-US" style="font-size:9.0pt;font-family:"Calibri Light",sans-serif;color:black;mso-fareast-language:EN-GB">TU Delft</span></b><span lang="EN-US" style="font-size:9.0pt;font-family:"Calibri Light",sans-serif;color:black;mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:9.0pt;font-family:"Calibri Light",sans-serif;color:black;mso-fareast-language:EN-GB">Faculty EEMCS, Dept. Intelligent Systems<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:9.0pt;font-family:"Calibri Light",sans-serif;color:black;mso-fareast-language:EN-GB">Van Mourik Broekmanweg 6, 2628 XE Delft<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:9.0pt;font-family:"Calibri Light",sans-serif;color:black;mso-fareast-language:EN-GB">Building 28, Office E05.060<o:p></o:p></span></p>
<p class="MsoNormal"><a href="http://joanagoncalves.org"><span lang="EN-US" style="font-size:9.0pt;font-family:"Calibri Light",sans-serif;mso-fareast-language:EN-GB">http://joanagoncalves.org</span></a></p>
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