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<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">Dear colleagues,</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin:0px"><br></span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">Also in the new academic year the BioSB research school, Wageningen University & Reserach </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">and Eindhoven University of Technology will organize the course:</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"><br></span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">*Integrated Modeling and Optimization*</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">12-16 December 2022, Wageningen University</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">Computational modelling is an absolute requisite to gain understanding of</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">the biological mechanisms underlying patterns observed in experimental</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">data. However, one could say that modelling is a craftsmanship, that can</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">only be learned via intense exercising and ‘learning by doing’. In this</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">course we offer the participants the possibility to learn and exercise the</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">modeling process and the optimization techniques needed to fit models to</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">data.</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">In the course the students will learn:</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> - to understand the common ground and the differences for applications</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> of dynamic modeling in metabolic, regulatory, signaling, and multi-scale</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> biological processes</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> - how to set-up a dynamic model to represent biological networks using</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> different interaction mechanisms</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> - to implement, simulate and analyze dynamic network models</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> - to understand the wide variety of problems in modelling that can be</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> solved with optimization ·</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> - to apply different types of numerical optimization methods: global and</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> local search methods: steepest descent, Levenberg-Marquardt, genetic</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> algorithms, linear programming.</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> - the combination of dynamic modeling and optimization to integrate</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> experimental data in modelling, estimate model parameters and design</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> experiments.</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> - to understand how numerical optimization (linear programming) works in</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> flux balance analysis to simulate metabolic network models.</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">Lecturers:</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt 36pt;font-size:10pt;font-family:"Courier New";text-indent:-18pt;background-color:white"><span lang="EN-GB" style="font-family:Symbol;margin:0px;color:rgb(89, 89, 89)"><span style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">·</span><span style="margin:0px"><span style="font-weight: normal; font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px;"> </span></span></span><span lang="EN-GB" style="font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px; color: rgb(89, 89, 89);">Prof. Natal van Riel, Eindhoven University of Technology (course coordinator)</span></pre>
<pre style="margin:0cm 0cm 0.0001pt 36pt;font-size:10pt;font-family:"Courier New";text-indent:-18pt;background-color:white"><span lang="EN-GB" style="font-family:Symbol;margin:0px;color:rgb(89, 89, 89)"><span style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">·</span><span style="margin:0px"><span style="font-weight: normal; font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px;"> </span></span></span><span lang="EN-GB" style="font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px; color: rgb(89, 89, 89);">Dr. Aalt-Jan van Dijk, Wageningen University & Research</span></pre>
<pre style="margin:0cm 0cm 0.0001pt 36pt;font-size:10pt;font-family:"Courier New";text-indent:-18pt;background-color:white"><span lang="EN-GB" style="font-family:Symbol;margin:0px;color:rgb(89, 89, 89)"><span style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">·</span><span style="margin:0px"><span style="font-weight: normal; font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px;"> </span></span></span><span lang="EN-GB" style="font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px; color: rgb(89, 89, 89);">Prof. Jaap Molenaar, Wageningen University & Research</span></pre>
<pre style="margin:0cm 0cm 0.0001pt 36pt;font-size:10pt;font-family:"Courier New";text-indent:-18pt;background-color:white"><span lang="EN-GB" style="font-family:Symbol;margin:0px;color:rgb(89, 89, 89)"><span style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">·</span><span style="margin:0px"><span style="font-weight: normal; font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px;"> </span></span></span><span lang="EN-GB" style="font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px; color: rgb(89, 89, 89);">Dr. Hans Stigter, Wageningen University & Research</span><span style="font-weight: normal; font-size: 12pt; font-family: "Times New Roman", Times, serif;"> </span><span lang="EN-GB" style="text-indent: -18pt; font-size: 12pt; font-family: "Times New Roman", Times, serif; color: rgb(89, 89, 89);"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt 36pt;font-size:10pt;font-family:"Courier New";text-indent:-18pt;background-color:white"><span lang="EN-GB" style="font-family:Symbol;margin:0px;color:rgb(89, 89, 89)"><span style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">·</span><span style="margin:0px"><span style="font-weight: normal; font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px;"> </span></span></span><span lang="EN-GB" style="font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px; color: rgb(89, 89, 89);">Dr. Robert Smith, Wageningen University & Research</span></pre>
<pre style="margin:0cm 0cm 0.0001pt 36pt;font-size:10pt;font-family:"Courier New";text-indent:-18pt;background-color:white"><span lang="EN-GB" style="font-family:Symbol;margin:0px;color:rgb(89, 89, 89)"><span style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">·</span><span style="margin:0px"><span style="font-weight: normal; font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px;"> </span></span></span><span lang="EN-GB" style="font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px; color: rgb(89, 89, 89);">Dr. Dragan Bosnacki, Eindhoven University of Technology</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">Target audience:</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span style="font-family: "Times New Roman", Times, serif; font-size: 12pt;">The course is aimed at PhD students with a background in bioinformatics, systems biology, computer science or a related field</span><span style="font-size: 12pt;">,</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin:0px"></span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px; color: rgb(89, 89, 89); background-color: white;">and life sciences. Participants from the private sector are also welcome. A working knowledge of mathematics,</span><span lang="EN-GB" style="margin:0px"></span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px; color: rgb(89, 89, 89); background-color: white;">especially differential equations, is recommendable, but we will distribute preparation material to be studied by students</span><span lang="EN-GB" style="margin:0px"></span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px; color: rgb(89, 89, 89); background-color: white;">missing the required background. Furthermore, at the start we offer a math refresher to help those participants who </span><span lang="EN-GB" style="margin:0px"></span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px; color: rgb(89, 89, 89); background-color: white;">are not (yet) involved in modelling on a daily basis.</span><span lang="EN-GB" style="margin:0px"></span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">More about the last year's edition:</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin:0px"><a href="https://eur02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.dtls.nl%2Fcourses%2Fintegrated-modeling-and-optimization%2F&data=05%7C01%7C%7Cdb94a8b4fa6941832f8c08da6bf9c254%7Ccc7df24760ce4a0f9d75704cf60efc64%7C0%7C0%7C637941017718028636%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=lMXj23wm05OtsLJrsGBzhsnIiOwAcawkkagtCNQdSR0%3D&reserved=0" target="_blank" rel="noopener noreferrer" data-auth="Verified" shash="Ch2+RJGrmuXx5Vw7VmeFswVuPwxp5jhzp19Xb+c1xBbpRMhlw/kMKLK5S9bKjCDkjGOZsbN7ZzbosDifoUgaovhYtWAtX3lFgwgO+Owxtrj2xujZ1ODxA8u5MS5xyDkfGCgk1qtFXWAIkm9VXAX1iK5yRmBakt7ovMZUud5kceU=" title="Original URL: https://www.dtls.nl/courses/integrated-modeling-and-optimization/. Click or tap if you trust this link." data-linkindex="13" style="margin:0px;color:blue;text-decoration:underline"><span style="font-family: "Times New Roman", Times, serif; font-size: 12pt;">https://www.dtls.nl/courses/integrated-modeling-and-optimization/</span></a></span></pre>
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<div style="font-size:11pt;font-family:Calibri, sans-serif;margin:0cm"><span style="font-size:16pt;font-family:"Segoe UI Light", sans-serif;margin:0px"><a href="https://eur02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.dtls.nl%2Fcourses%2Fintegrated-modeling-and-optimization%2F&data=05%7C01%7C%7Cdb94a8b4fa6941832f8c08da6bf9c254%7Ccc7df24760ce4a0f9d75704cf60efc64%7C0%7C0%7C637941017718028636%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=lMXj23wm05OtsLJrsGBzhsnIiOwAcawkkagtCNQdSR0%3D&reserved=0" target="_blank" rel="noopener noreferrer" data-auth="Verified" shash="Ch2+RJGrmuXx5Vw7VmeFswVuPwxp5jhzp19Xb+c1xBbpRMhlw/kMKLK5S9bKjCDkjGOZsbN7ZzbosDifoUgaovhYtWAtX3lFgwgO+Owxtrj2xujZ1ODxA8u5MS5xyDkfGCgk1qtFXWAIkm9VXAX1iK5yRmBakt7ovMZUud5kceU=" title="Original URL: https://www.dtls.nl/courses/integrated-modeling-and-optimization/. Click or tap if you trust this link." data-linkindex="15" style="margin:0px;color:blue;text-decoration:underline"><span style="font-family: "Times New Roman", Times, serif; font-size: 12pt;">Integrated
modeling and optimization - Dutch Techcentre for Life Sciences</span></a></span></div>
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<div style="font-size:11pt;font-family:Calibri, sans-serif;margin:0cm"><span style="font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px; color: rgb(102, 102, 102);">Course date 13-17 December 2021, Wageningen Location: The course will
be held at: Forum Building (building nr 102), with number B0409. A Biocafe (on Thursday) will be held in “The Spot” in Building Orion (gebouw nummer 103) in the Wageningen…</span></div>
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<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";text-align:center;background-color:white"><span lang="EN-GB" style="font-size: 12pt; font-family: "Times New Roman", Times, serif; margin: 0px;"></span><span lang="EN-GB" style="margin:0px"></span></pre>
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<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">More details about the programme and the registration will follow soon. </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">Please feel free to contact Dragan Bosnacki (D.Bosnacki@tue.nl) for more information.</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">---------------------</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">*About BioSB*</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">The Netherlands Bioinformatics and Systems Biology research school (BioSB)</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">is the national platform in which the Dutch community of researchers in</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">bioinformatics and systems biology is organized. BioSB also organizes:</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> 1. fundamental and advanced post-graduate courses</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> <</span><span lang="EN-GB" style="margin:0px"><a href="https://eur02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.biosb.nl%2Feducation%2Fcourse-portfolio%2F&data=05%7C01%7C%7Cdb94a8b4fa6941832f8c08da6bf9c254%7Ccc7df24760ce4a0f9d75704cf60efc64%7C0%7C0%7C637941017718028636%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=dVkjQj1XGJZw7b4GNFAB%2Bd%2FeJjxp3TOvX%2FqsGyR%2BgQ4%3D&reserved=0" target="_blank" rel="noopener noreferrer" data-auth="Verified" shash="sKVHTA6K6grUahfwCx17c2FR3WZ8gkl6lWU+K5DuTvCZQs9SSR2vonvJBO28bZmdZUEgK+q9e4Mt9s0GJzBWMeW7NUz3CJTRtw27ada6nWKbIVxQOWF5TcNtri/r/jDo5iwtLbPCEYqkPjjLmm2mnJp7+FGrxeO6K8R0yZP50mg=" title="Original URL: https://www.biosb.nl/education/course-portfolio/. Click or tap if you trust this link." data-linkindex="17" style="margin:0px;color:blue;text-decoration:underline"><span style="font-family: "Times New Roman", Times, serif; font-size: 12pt;">https://eur04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.biosb.nl%2Feducation%2Fcourse-portfolio%2F&data=04%7C01%7Cp.d.moerland%40amsterdamumc.nl%7Cb50e6cc624ae436c8a7608d88ff446ff%7C68dfab1a11bb4cc6beb528d756984fb6%7C0%7C0%7C637417626609229476%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=2zzuqQYvfLwhU6fMZDwIKvyMwD5xlzJITlRpE4WYLzw%3D&reserved=0</span></a></span><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">></span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> 2. the yearly BioSB conference</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> <</span><span lang="EN-GB" style="margin:0px"><a href="https://eur02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.biosb.nl%2Fconferences%2F&data=05%7C01%7C%7Cdb94a8b4fa6941832f8c08da6bf9c254%7Ccc7df24760ce4a0f9d75704cf60efc64%7C0%7C0%7C637941017718028636%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=0XQ0pwM1WywDilULilN358wPF6phGFQrGERqKLCpm3I%3D&reserved=0" target="_blank" rel="noopener noreferrer" data-auth="Verified" shash="Zyy1+gcVQh0s5hqepxE05WnxxuhDP9yv0h7DVQ4eOf3T5fEsv7F5VJgGoKoIRn/Jx7w3x+9LC1qZfvxdfKEufTBz8Z9qwjmcH4/ggbvSmyfLJ0ABpTXbdqdquwb8e4rdgr2Z6GW5A0AMUwydmIq9Q9y0qJzfTj4ladvYsQZlkXA=" title="Original URL: https://www.biosb.nl/conferences/. Click or tap if you trust this link." data-linkindex="18" style="margin:0px;color:blue;text-decoration:underline"><span style="font-family: "Times New Roman", Times, serif; font-size: 12pt;">https://eur04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.biosb.nl%2Fconferences%2F&data=04%7C01%7Cp.d.moerland%40amsterdamumc.nl%7Cb50e6cc624ae436c8a7608d88ff446ff%7C68dfab1a11bb4cc6beb528d756984fb6%7C0%7C0%7C637417626609229476%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=FGCOsjW0GYbZnwf1xzrtpBgjESPAdBSsiyomW5Ftups%3D&reserved=0</span></a></span><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">></span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> 3. hot topics meetings</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> <</span><span lang="EN-GB" style="margin:0px"><a href="https://eur02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.biosb.nl%2Fhottopics%2F&data=05%7C01%7C%7Cdb94a8b4fa6941832f8c08da6bf9c254%7Ccc7df24760ce4a0f9d75704cf60efc64%7C0%7C0%7C637941017718028636%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=SufnO6EqsnuKT5Ln1jxq%2BSsKSimoGT%2BV89HpofAKIco%3D&reserved=0" target="_blank" rel="noopener noreferrer" data-auth="Verified" shash="ey1qPzhKZ/yKLNor/KMnNaMN70ZSlsftra2qYkCSyrHZVBRHrq6f6/FS2InQSJq2VCc5MmiPUQFFLyAlhk72n5VFW44fA3dY+tI6ldmAX8OKzohIFMC4V6eybwIQQU6K+VCDZBkAitHrOFE5QFalbEFAqYIHofuJCjQ1yu0i3HI=" title="Original URL: https://www.biosb.nl/hottopics/. Click or tap if you trust this link." data-linkindex="19" style="margin:0px;color:blue;text-decoration:underline"><span style="font-family: "Times New Roman", Times, serif; font-size: 12pt;">https://eur04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.biosb.nl%2Fhottopics%2F&data=04%7C01%7Cp.d.moerland%40amsterdamumc.nl%7Cb50e6cc624ae436c8a7608d88ff446ff%7C68dfab1a11bb4cc6beb528d756984fb6%7C0%7C0%7C637417626609239472%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=IEKfjekFje1m5U1ariGhzxNI%2F9QRRfXqZ6HMSQYyUVI%3D&reserved=0</span></a></span><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">></span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"> </span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">The aim of the BioSB research school is to offer PhD students, postdocs and</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">senior researchers a vibrant environment for their scientific development</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">as well as education in bioinformatics and systems biology. In addition,</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">BioSB acts as a parent organization for YoungCB</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;"><</span><span lang="EN-GB" style="margin:0px"><a href="https://eur02.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.youngcb.nl%2F&data=05%7C01%7C%7Cdb94a8b4fa6941832f8c08da6bf9c254%7Ccc7df24760ce4a0f9d75704cf60efc64%7C0%7C0%7C637941017718028636%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=xUUf%2BnrnFmY8xc4XaDOhArNQbwIjd4g6u64x28aKVBM%3D&reserved=0" target="_blank" rel="noopener noreferrer" data-auth="Verified" shash="Sw95PbS3IB5jdCwUsHsu22y4o2k7/8t2wesK5kRuQAQBj77XJ9/65T7gm4OZJBRaxyrZ5PXnA44G/mwfvI9xjh0Vg7ExQDzzzq02b3AlnGY8WO36/zw90UFFrnMce5r0bJZLrjU+7Z3zatPnBRsCYzRTEpSxfJyWCCvsgKCQFm8=" title="Original URL: http://www.youngcb.nl/. Click or tap if you trust this link." data-linkindex="20" style="margin:0px;color:blue;text-decoration:underline"><span style="font-family: "Times New Roman", Times, serif; font-size: 12pt;">https://eur04.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.youngcb.nl%2F&data=04%7C01%7Cp.d.moerland%40amsterdamumc.nl%7Cb50e6cc624ae436c8a7608d88ff446ff%7C68dfab1a11bb4cc6beb528d756984fb6%7C0%7C0%7C637417626609239472%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=s0JGs6hegGU%2BskTBgKnAYY6fz5U%2B8cSifF9QF0IbILo%3D&reserved=0</span></a></span><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">>,</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">the official Regional Student Group (RSG) of the International Society of</span></pre>
<pre style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:"Courier New";background-color:white"><span lang="EN-GB" style="margin: 0px; font-family: "Times New Roman", Times, serif; font-size: 12pt;">Computational Biology (ISCB).</span></pre>
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