[Seminars] PSB event reminder

[contact at psb.vib-ugent.be]

Calendar Name: seminars
Scheduled for: Tuesday, April 20 2010, 11:00 - 12:30
Event text:    Catherine Perrot-Rechenmann
	       
	       Institut des Sciences du Végétal (ISV), CNRS
	       Gif sur Yvette
	       FRANCE
Details:       “Cross-talk between ABP1 and TIR1/AFB auxin receptors”
	       
	       ABSTRACT
	       The phytohormone auxin is a major regulator of plant
	       growth and development. Many aspects of these processes
	       depend on the multiple controls exerted by auxin on
	       cellular responses as cell expansion and cell division,
	       and mediated at the molecular level by the regulation of
	       auxin-responsive genes.	Two classes of auxin receptors
	       have been identified to date: first, the TIR1/AFB F-box
	       proteins which are part of ubiquitin E3 ligase complexes
	       and, according to the current auxin signalling model
	       (reviewed by 1), recruit the AUX/IAA transcriptional
	       repressors in the presence of auxin to induce their
	       ubiquitination and degradation by the 26S proteasome;
	       second, the long-standing and unique auxin binding
	       protein 1, ABP1, initially identified on its capacity to
	       bind auxin and demonstrated to induce activation of ion
	       fluxes at the plasma after auxin binding. Recently, the
	       detailed characterization of conditional ABP1 knock-down
	       plants 2,3 revealed that ABP1 is required for almost all
	       auxin-mediated responses including modulation of gene
	       expression. In consequence, TIR1/AFB and ABP1 appear to
	       share the regulation of auxin responsive genes. We have
	       investigated the relationship between the TIR1/AFBs- and
	       ABP1-mediated pathways. We have further analyzed the
	       requirement of ABP1 for auxin mediated gene expression
	       in roots and developed biochemical and genetic
	       approaches to analyze its functional interaction with
	       the SCFTIR1/AFB pathway. Original data leads to a novel
	       model integrating ABP1 and SCFTIR1/AFBs into a
	       sophisticated multicomponent auxin signaling pathway,
	       essential for regulation of auxin responses.
	       
	       1. Chapman EJ, Estelle M: Annu Rev Genet 2009,
	       43:265-285.
	       2. Braun N, Wyrzykowska J, Muller P, David K, Couch D,
	       Perrot-Rechenmann C, Fleming AJ Plant Cell 2008,
	       10:2746-2762.
	       3. Tromas A, Braun N, Muller P, Khodus T, Paponov IA, et
	       al.  PLoS One 2009, 4:e6648.

-------------- next part --------------
An HTML attachment was scrubbed...
URL: https://maillist.psb.ugent.be/mailman/private/seminars/attachments/20100418/d63228b8/attachment.html