[Seminars] PSB event reminder

[contact at psb.vib-ugent.be]

Calendar Name: seminars
Scheduled for: Thursday, August 26 2010, 11:00 - 12:30
Event text:    Prof Ian Small
	       
	       Director, ARC Centre of Excellence in Plant Energy
	       Biology
	       University of Western Australia
	       AUSTRALIA
Details:       "Perfectly Prepared RNA: getting transcripts ready for
	       translation"
	       
	       ABSTRACT
	       Ian Small
	       
	       ARC Centre of Excellence in Plant Energy Biology,
	       University of Western Australia, Crawley
	       6009 WA, Australia
	       
	       Organelle gene expression involves a series of more or
	       less coupled processes from
	       transcription through transcript processing to
	       translation. Many of the events that occur
	       during these processes require sequence recognition by
	       RNA processing factors. It has
	       become abundantly clear over the last decade that in
	       plants, pentatricopeptide repeat
	       (PPR) proteins are the most numerous of these factors,
	       with a bewildering array of 450+
	       family members in most angiosperms studied to date.
	       The development of screens for RNA processing defects
	       has enabled the identification of
	       the functions of some of these proteins by reverse
	       genetics; several other PPR genes have
	       been singled out by forward genetic screens for
	       phenotypes that involve defects in
	       organelle function. The RNA targets and molecular
	       functions for over 40 PPR proteins have
	       been characterised, allowing the first generalisations
	       to be drawn concerning their modes
	       of action.
	       Although the functions of over 90% of the PPR family are
	       still to be worked out, it is
	       becoming clear that certain subclasses of the family
	       have a strong tendency to be
	       associated with particular molecular processes such as
	       transcription, splicing or RNA
	       editing.
	       Progress is being made at modelling the structure of PPR
	       proteins and understanding how
	       they recognise specific RNA sequences, offering hope
	       that they could form the basis for a
	       new way of designing custom-made RNA binding proteins
	       for biotechnology

-------------- next part --------------
An HTML attachment was scrubbed...
URL: https://maillist.psb.ugent.be/mailman/private/seminars/attachments/20100824/a261c03c/attachment.html