[Seminars] PSB event reminder

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Calendar Name: seminars
Scheduled for: Thursday, June 21 2012, 11:00 - 12:30
Event text:    Prof Pierre Hilson
	       
	       VIB, Dept. of Plant Systems Biology
	       Ghent University
	       
	       Gent
	       BELGIUM
Details:       “Signaling peptides regulate plant tropic growth and
	       root development”
	       
	       ABSTRACT:
	       
	       Plant growth and development are coordinated by an array
	       of intercellular signals, including phytohormones and
	       secreted peptides. A cursory analysis of plant genomes
	       suggests that the role of the latter class of molecules
	       may still be underestimated. Furthermore, while both
	       classes can be implicated in the same developmental
	       processes, little is known about the interplay between
	       phytohormone action and peptide signaling within the
	       cellular microenvironment. We have shown that
	       plant-specific genes coding for small secretory
	       peptides, designated GOLVEN (GLV), modulate the
	       distribution of the phytohormone auxin in Arabidopsis.
	       The deregulation of the GLV function impairs the
	       formation of auxin gradients via PIN proteins, thereby
	       altering the reorientation of shoots and roots after a
	       gravity stimulus, affecting meristem size, or preventing
	       the proper development of lateral roots. We have also
	       identified proteolytic enzymes important for the
	       production of the bioactive GLV signal and will discuss
	       their potential regulation.
	       A complementary research project will be introduced. We
	       have built a high-content screening platform to study
	       the cellular phenotypes of isolated plant cells. This
	       system has been optimized to track the proliferation of
	       isolated Arabidopsis cells with high-throughput and
	       robotized protocols. The properties of several molecules
	       identified in large-scale screens will be described.

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