[Seminars] PSB event reminder

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Calendar Name: seminars
Scheduled for: Monday, March 12 2012, 11:00 - 11:30
Event text:    Prof Silke Robatzek 
	       
	       The Sainsbury Laboratory
	       
	       Norwich
	       UNITED KINGDOM
Details:       “Plants communicating with pathogens: membranes in
	       motion and cellular defense”
	       
	       ABSTRACT
	       Cell surface receptors of plant cells constitute
	       recognition sites to detect invading pathogens and to
	       active defenses. Arabidopsis FLS2 encodes the receptor
	       kinase for bacterial flagellin (flg22) and is required
	       for immunity against a broad-spectrum of potentially
	       pathogenic bacteria. Upon flg22 perception FLS2
	       accumulates at plasma membrane microdomains and is
	       internalized. Although receptor trafficking became a
	       focus of research in the past years, there is largely
	       nothing known about downstream molecules and regulatory
	       components of receptor endocytosis. I will present
	       quantitative high throughput confocal imaging in plants
	       and will discuss results from our current research,
	       which addresses the identity of the FLS2 endosome,
	       molecular components regulating FLS2 endocytosis, and
	       the interception of FLS2 endocytosis and flg22
	       signaling. These results provide good evidences for a
	       role of late endosomes/multivesicular bodies in plant
	       immunity. To further study cellular defenses we focus on
	       stomatal closure as a first layer of plant immunity. I
	       will describe approaches using high throughput confocal
	       imaging for the genetic dissection of stomata response
	       pathways, and present exciting data how pathogens
	       inhibit stomatal closure by interference with hormonal
	       signaling. Altogether, these studies allow us to better
	       understand the molecular mechanisms underlying the
	       subcellular changes in plant-pathogen interactions.

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