[Seminars] You are invited to attend “Mapping the Cysteine Redoxome” ON December 22, 2022

Delphine Verspeel delphine.verspeel at psb.vib-ugent.be
Tue Nov 22 10:04:49 CET 2022


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'' Mapping the Cysteine Redoxome '' 


Prof Jing Yang 




National Center for Protein Sciences 
CHINA 






Thursday, December 22, 2022 
11:00 





























The nucleophilic thiol group (Cys-SH) allows cysteine to undergo a broad range of redox modifications, such as sulfenylation (Cys-SOH), sulfinylation (Cys-SO2H). Emerging evidence suggests that cysteine redox modifications are well-controlled, site-specific cellular events, which play important roles in regulating many biological processes, such as autophagy, cellular metabolism, inflammation, cell cycle and cell death under physiological and pathological contexts. Efforts to understand their underlying mechanisms have been hampered due to limitations of methods for globally analyzing site-specific protein targets and redox dynamics. We have recently developed several chemoproteomic approaches to globally map and to quantify Cys-SH, Cys-SOH and Cys-SO2H in complex proteomes, providing versatile opportunities to study cysteine-mediated redox networks in a range of biological processes and adaptive responses in physiology and pathophysiology. 









Jozef Schell seminar room 
Technologiepark 71 - 9052 




Invited by Prof Dirk Inzé, Prof Frank Van Breusegem and Prof Kris Gevaert (VIB-CMB) 

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Genome editing, cutting-edge technology for a sustainable agriculture 

VIB-UGent Center for Plant Systems Biology Ghent University 
Technologiepark-Zwijnaarde 71 
9052 Ghent-Belgium 
Phone: +32(0)9 331 38 00 
[ http://www.psb.vib-ugent.be/ | https://www.psb.ugent.be/ ] 













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