[Seminars] Seminar Associate Prof Mathew Lewsey TOMORROW at 11 am in the Schell room

Delphine Verspeel delphine.verspeel at psb.vib-ugent.be
Mon Oct 24 11:00:03 CEST 2022


REMINDER 


Van: "Delphine Verspeel" <delphine.verspeel at psb.vib-ugent.be> 
Aan: "meetings" <meetings at psb.vib-ugent.be> 
Verzonden: Dinsdag 11 oktober 2022 17:04:14 
Onderwerp: You are invited to attend “Gene regulatory dynamics of germinating seeds from bulk tissue to single-cell resolution” ON October 25, 2022 

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'' Gene regulatory dynamics of germinating seeds from bulk tissue to single-cell resolution '' 


Associate Prof Mathew Lewsey 





La Trobe Institute for Sustainable Agriculture and Food 

La Trobe University 
Bundoora 
AUSTRALIA 





Tuesday, October 25, 2022 
11:00 
































“Seeds provide 70% of global food resources, being the most valuable output from plant production. They also play a critical role in agriculture because the lifecycle of most crops begins from seed germination. Uniform germination enables growers to achieve optimal plant-spacing and harvesting time. Despite this importance, we do not have a complete understanding of how seed germination is regulated, which limits our ability to improve its properties. We have made much progress identifying regulators by traditional bulk-tissue 'omics approaches. Through these we have discovered transcription factors that control both gene expression and the progress of germination. However, the seed is a complex structure comprised of many tissues and cell-types, each of which have distinct properties. Changes in gene expression occur in these cell-types throughout germination and are expected to be context-dependent, to enable spatiotemporal control of cellular processes. To better understand how gene expression is controlled within individual seed cell-types we have carried out single-cell RNA-Seq in germinating Arabidopsis embryos. We analysed seeds at three time points after stratification: 12 hours (mucilage excretion), 24 hours (testa rupture) and 48 hours (radicle emergence). We then identified individual cell-types within the embryo, annotated their identities and studied how they changed over time. This study provides unprecedented insight into the transcriptome of the germinating Arabidopsis embryo and genome regulatory network during seed germination. It will help us to develop practical solutions to promote the seed-to-seedling transition and to ensure germination happens uniformly at the right time.” 





















Jozef Schell seminar room 
Technologiepark 71 - 9052 




Invited by Prof Dirk Inzé and Prof Klaas Vandepoele 

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Genome editing, cutting-edge technology for a sustainable agriculture 

VIB-UGent Center for Plant Systems Biology Ghent University 
Technologiepark-Zwijnaarde 71 
9052 Ghent-Belgium 
Phone: +32(0)9 331 38 00 
[ http://www.psb.vib-ugent.be/ | https://www.psb.ugent.be/ ] 









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