[Seminars] Seminar Prof Anne Osbourn TOMORROW at 11 am in the Schell room

[Delphine Verspeel]

REMINDER 


Van: "Delphine Verspeel" <delphine.verspeel at psb.vib-ugent.be> 
Aan: "meetings" <meetings at psb.vib-ugent.be> 
Verzonden: Vrijdag 19 januari 2024 17:18:04 
Onderwerp: You are invited to attend “Harnessing plant metabolic diversity for food and health applications” ON February 22, 2024 


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“ Harnessing plant metabolic diversity for food and health applications ” 



Prof Anne Osbourn 



John Innes Centre 
UNITED KINGDOM 








Thursday, February 22, 2024 
11:00 




Plants produce a wealth of natural products. The vast majority of the natural product diversity encoded by plant genomes remains as yet untapped. The explosion in plant genome sequence data, coupled with affordable DNA synthesis and new DNA assembly technologies, now offer unprecedented opportunities to harness the full breadth of plant natural product diversity and generate novel molecules in foreign hosts using synthetic biology approaches. The recent discovery that genes for the synthesis of different kinds of natural products are organised in biosynthetic gene clusters in plant genomes opens up opportunities for mining for new pathways and chemistries. This advance, in combination with powerful new transient plant expression technology, is enabling the development of rational strategies to produce known and new-to-nature chemicals tailored for food, health and industrial applications. This presentation will focus on our work on developing a translational synthetic biology pipeline for rapid preparative access to plant natural products and novel analogs using synthetic biology approaches, focusing in particular on the elucidation of the pathway for saponin vaccine adjuvants from the Chilean soapbark tree. Our results enable for the first time the production of soapbark vaccine adjuvants in a heterologous expression system and open the way for new routes to access and engineer natural and new-to-nature immunostimulants. 







Jozef Schell seminar room 
Technologiepark 71 - 9052 






Invited by Prof Yves Van de Peer and Prof Alain Goossens 

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Genome editing, cutting-edge technology for a sustainable agriculture 

VIB-UGent Center for Plant Systems Biology Ghent University 
Technologiepark-Zwijnaarde 71 
9052 Ghent-Belgium 
Phone: +32(0)9 331 38 00 
[ http://www.psb.vib-ugent.be/ | https://www.psb.ugent.be/ ] 




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