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<p class="MsoNormal"><span lang="EN-US" style="color:#1F497D">Dear all,<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:#1F497D">The research by Prof. Jeroen Raes on human gut flora metagenomics has received a lot of media attention (see
<a href="http://www.vib.be/en/research/scientists/Pages/Jeroen-Raes-Lab.aspx">http://www.vib.be/en/research/scientists/Pages/Jeroen-Raes-Lab.aspx</a> for an overview). Next Tuesday this expert who performed his PhD and postdoc research at Ghent University,
will present you his latest insights.</span><span lang="EN-US"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:#1F497D"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span lang="EN-US" style="font-size:12.0pt;font-family:"Verdana",sans-serif;color:#2F2B2A"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:12.0pt;font-family:"Cambria",serif">The BIG N2N seminar series is a Specialist Course in the Doctoral Schools training program</span><span lang="EN-US" style="font-size:12.0pt;font-family:"Verdana",sans-serif;color:#2F2B2A"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:12.0pt;font-family:"Verdana",sans-serif;color:#2F2B2A"><o:p> </o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-US" style="font-size:20.0pt;font-family:"Times New Roman",serif;mso-fareast-language:ZH-CN">“Towards population-level microbiome monitoring: the Flemish Gut Flora Project”<o:p></o:p></span></b></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:12.0pt;font-family:"Verdana",sans-serif;color:#2F2B2A"><o:p> </o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-US" style="font-size:18.0pt;font-family:"Times New Roman",serif;mso-fareast-language:ZH-CN">Prof. Dr. Jeroen Raes<o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN" style="font-size:18.0pt;font-family:"Times New Roman",serif;mso-fareast-language:ZH-CN"><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-US" style="font-size:14.0pt;font-family:"Times New Roman",serif;mso-fareast-language:ZH-CN">KUL, VIB lab for Bioinformatics and (eco-)systems biology</span></b><b><span lang="EN" style="font-size:14.0pt;font-family:"Times New Roman",serif;mso-fareast-language:ZH-CN"><o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN" style="font-size:14.0pt;font-family:"Times New Roman",serif;mso-fareast-language:ZH-CN"><o:p> </o:p></span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span lang="EN-US" style="font-size:18.0pt;font-family:"Times New Roman",serif;background:yellow;mso-highlight:yellow;mso-fareast-language:ZH-CN">April 19, 2016 (11:00)</span></b><b><span lang="EN-US" style="font-size:18.0pt;font-family:"Times New Roman",serif;mso-fareast-language:ZH-CN"><o:p></o:p></span></b></p>
<p class="MsoNormal" align="center" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:center">
<b><span lang="EN-US" style="font-size:13.5pt;font-family:"Times New Roman",serif;mso-fareast-language:ZH-CN">Jozef Schell seminar room, Technologiepark 927 - 9052 Zwijnaarde<o:p></o:p></span></b></p>
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<b><u><span lang="EN-US" style="font-size:13.5pt;font-family:"Times New Roman",serif;color:blue;mso-fareast-language:ZH-CN"><o:p><span style="text-decoration:none"> </span></o:p></span></u></b></p>
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<b><u><span lang="EN-US" style="font-size:13.5pt;font-family:"Times New Roman",serif;color:blue;mso-fareast-language:ZH-CN"><a href="http://www.bign2n.ugent.be/events">www.bign2n.ugent.be/events</a><o:p></o:p></span></u></b></p>
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<span lang="EN-US" style="font-size:12.0pt;font-family:"Cambria",serif"><a href="http://www.bign2n.ugent.be/node/232"><b><span style="font-size:13.5pt;font-family:"Times New Roman",serif;color:blue;mso-fareast-language:ZH-CN">www.bign2n.ugent.be/node/232</span></b></a></span><b><u><span lang="EN-US" style="font-size:13.5pt;font-family:"Times New Roman",serif;color:blue;mso-fareast-language:ZH-CN"><o:p></o:p></span></u></b></p>
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<b><u><span lang="EN-US" style="font-size:12.0pt;font-family:"Cambria",serif;color:blue"><o:p><span style="text-decoration:none"> </span></o:p></span></u></b></p>
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<b><span lang="EN-US" style="font-size:13.5pt;font-family:"Times New Roman",serif;mso-fareast-language:ZH-CN">Abstract<o:p></o:p></span></b></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="font-size:12.0pt;font-family:"Times New Roman",serif;color:#2F2B2A">Alterations in the gut microbiota have been linked to various pathologies, ranging from inflammatory bowel disease
and diabetes to cancer. Although large numbers of clinical studies aiming at microbiome-based disease markers are currently being performed, our basic knowledge about the normal variability of the human intestinal microbiota and the factors that determine
this still remain limited. Here, I will present a large-scale study of the gut microbiome variation in a geographically confined region (Flanders, Belgium). A cohort of >5000 individuals from the normal population is sampled for microbiome analysis and extensive
metadata covering demographic, health- and lifestyle-related parameters is collected. Based on this cohort, a large-scale cross-sectional study of microbiome variability in relation to health as well as parameters associated to microbiome composition is being
performed. In this presentation, I will discuss our experiences in large-scale microbiome monitoring, show how the development of dedicated computational approaches can assist in microbiome analysis and interpretation, and first results coming out of this
effort.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-family:"Verdana",sans-serif;color:#2F2B2A"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-family:"Verdana",sans-serif;color:#2F2B2A"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">Kind regards,<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">Katrijn Vannerum<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:black;mso-fareast-language:NL-BE">PhD<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:black;mso-fareast-language:NL-BE">Project manager<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:black;mso-fareast-language:NL-BE">BIG N2N (Bioinformatics Institute Ghent From Nucleotides to Networks)<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="FR" style="color:black;mso-fareast-language:NL-BE">Ghent University<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="FR" style="color:black;mso-fareast-language:NL-BE"><a href="http://www.bign2n.ugent.be/"><span style="color:blue">http://www.bign2n.ugent.be/</span></a><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:black;mso-fareast-language:NL-BE">twitter: @N2N_UGent</span><span style="color:black;mso-fareast-language:NL-BE"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:black;mso-fareast-language:NL-BE"><a href="mailto:Katrijn.Vannerum@UGent.be"><span style="color:blue">Katrijn.Vannerum@UGent.be</span></a></span><span style="color:black;mso-fareast-language:NL-BE"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:black;mso-fareast-language:NL-BE">Technologiepark 927</span><span style="color:black;mso-fareast-language:NL-BE"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:black;mso-fareast-language:NL-BE">9052 Gent, Belgium</span><span style="color:black;mso-fareast-language:NL-BE"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:black;mso-fareast-language:NL-BE">+32 (0)9 331 36 85</span><span style="color:black;mso-fareast-language:NL-BE"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:black;mso-fareast-language:NL-BE"><img border="0" width="174" height="91" id="Picture_x0020_1" src="cid:image003.jpg@01D196F8.88017DF0" alt="logo_BIG N2N_signature"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:black;mso-fareast-language:NL-BE"> <o:p></o:p></span></p>
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