<html><body><div style="font-family: verdana,helvetica,sans-serif; font-size: 9pt; color: #000000"><div><br></div><div data-marker="__QUOTED_TEXT__"><div><div style="font-family: verdana, helvetica, sans-serif; font-size: 9pt; color: rgb(0, 0, 0);"><div><div><div style="font-family: verdana, helvetica, sans-serif; font-size: 9pt; color: rgb(0, 0, 0);"><div><div><div style="font-family: verdana, helvetica, sans-serif; font-size: 9pt; color: rgb(0, 0, 0);"><div style="font-family: verdana, helvetica, sans-serif; font-size: 9pt; color: rgb(0, 0, 0);"><div style="text-align: center;"><span style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;">You are receiving this e-mail because you subscribed to our seminars announcements and reminders service at </span><a href="https://maillist.psb.ugent.be/mailman/listinfo/seminars" rel="nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer" style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;" target="_blank">https://maillist.psb.ugent.be/mailman/listinfo/seminars</a><span style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;">.</span><div><div><div><div id="zimbraEditorContainer" class="111"><p style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;"><br><span style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;"> <img data-mce-src="cid:8b0b183ccdc8705b9069736bc3b74ab95fe3b4c9@zimbra" pnsrc="cid:8b0b183ccdc8705b9069736bc3b74ab95fe3b4c9@zimbra" src="cid:8b0b183ccdc8705b9069736bc3b74ab95fe3b4c9@zimbra"></span></p><h1 style="color: rgb(0, 0, 0); font-family: "segoe ui", "lucida sans", sans-serif; font-size: 9pt; font-style: normal; letter-spacing: normal; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px;"><br></h1><p><i style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt; font-weight: bold;"><i style="font-family: verdana, helvetica, sans-serif; font-size: 9pt; font-weight: bold;"><span lang="EN-US"><span style="font-size: 16pt; font-style: normal;">''<span style="font-family: verdana, helvetica, sans-serif;"><i><span lang="EN-US" style="font-size: 16pt;">New insights in the root apical meristem maintenance and lateral root development in Arabidopsis thalian<b>a</b></span></i></span></span></span></i></i><b style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 16pt;">''</b></p><h1 style="color: rgb(0, 0, 0); font-family: "segoe ui", "lucida sans", sans-serif; font-size: 9pt; font-style: normal; letter-spacing: normal; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; background-color: rgb(255, 253, 251);"><span style="background-color: rgb(255, 255, 255); font-family: verdana, helvetica, sans-serif; font-size: 9pt;"> </span><br></h1><p style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;"><br></p><h2 style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;"><span style="font-size: 24px;">Prof Joseph G. Dubrovsky</span><br></h2><h2 class="MsoBodyText2" style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt; margin: 0px;"><br></h2><p class="MsoNormal" style="margin: 0px; text-align: center;"><br></p><div><strong style="font-size: 9pt;"><span style="font-size: 14pt; background-color: rgb(255, 253, 251); float: none; display: inline !important;">Department of Plant Molecular Biology</span></strong></div><div><strong style="font-size: 9pt;"><span style="font-size: 14pt; background-color: rgb(255, 253, 251); float: none; display: inline !important;">Institute of Biotechnology</span></strong></div><div><div><strong><span style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 14pt; font-style: normal; letter-spacing: normal; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; background-color: rgb(255, 253, 251); float: none; display: inline !important;">National Autonomous University of Mexico (UNAM)</span></strong><div><strong><span style="font-size: 18.6667px;">MEXICO</span></strong><br></div></div></div><h2 class="MsoBodyText2" style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt; margin: 0px;"><br></h2><p class="MsoBodyText2" style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt; margin: 0px;"><br></p><p style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;"><br><br></p><h2 style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;"><span style="font-size: 16pt;">Monday, May 22, 2023</span><br><span style="font-size: 16pt;">11:00</span></h2><p class="MsoNormal" align="center" style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt; text-align: center; margin: 0px;"><span lang="EN-US" style="font-size: 16pt; font-family: calibri, sans-serif;"> </span></p><p class="xmsonormal" style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt; margin: 0px; text-align: justify; background: rgb(255, 253, 251);"><br></p><p class="MsoNormal" style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt; margin: 0px; text-align: justify;"><br></p><p class="MsoNormal" style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt; margin: 0px; line-height: 150%; text-align: center;"><br></p><p class="MsoNoSpacing" style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt; margin: 0px; text-align: justify;"><br></p><p class="MsoNormal" style="margin: 0px;"> </p><p class="MsoNormal" style="text-align: justify; margin: 0px;"><span lang="EN-US" style="font-size: 11pt; font-family: calibri, sans-serif; color: black;">Root system possess a modular organization, in which the root apical meristem (RAM) maintenance and root growth are essential for new root formation. In my lab we study the RAM maintenance and lateral root (LR) formation, and I will discuss our recent discoveries and novel understanding of some processes related to the root system formation. In search of new regulatory pathways of RAM maintenance, we isolated several mutans that are incapable of root growth. This work revealed a new metabolically-dependent regulatory pathway involved in RAM maintenance. Specifically, we established that THREONINE SYNTHASE 1 (TSY1) is critical for stem cell activity independently of the classical <i>SHR-SCR, PLT</i>, and <i>WOX5</i> regulatory pathways. Using mathematical modeling we were able to reproduce <i>in silico </i>determinate root growth in loss-of-function mutants and predict that not only synthesis but also catabolism of Thr is essential for the RAM maintenance. This work also demonstrated that the RAM proliferation and transition domains can be uncoupled. The RAM function is fundamental for the new root axis and LR root formation, and in the second part of my seminar I will present new insights that show that LR does not start from a preselected group of cells, but in most cases from a single founder cell (FC). We established that after specification of the first FC, a dynamic and non-stereotypic process of FC recruitment from neighboring pericycle cells is taking place. FC recruitment occurs in longitudinal and tangential directions and culminates in the formation of a morphogenetic field of FCs. The recruitment of phloem-pole pericycle to FCs and the role of parent root tissues in the LR formation will also be discussed. I will present our recent data that show how parental root procambium in the vicinity with the FCs participates in the formation of the xylem bridge underlying vascular continuity between all root types in the root system. </span></p><p class="MsoNormal" style="margin: 0px;"> <br></p><br><p class="MsoNoSpacing" style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt; margin: 0px; text-align: justify;"><br></p><p style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;"><br></p><p class="MsoNormal" style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt; text-align: justify; margin: 0px;"><br></p><p class="MsoNormal" style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt; text-align: justify; margin: 0px;"><br></p><h3 style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;">Jozef Schell seminar room<br>Technologiepark 71 - 9052 </h3><p style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;"><br><br><br><br><span style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;">Invited by Prof Dirk Inzé and Prof Lieven De Veylder</span></p><center style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;"><br><br><span style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;">If you do not wish to receive this information anymore, please unsubscribe from future mailings at </span><a href="https://maillist.psb.ugent.be/mailman/listinfo/seminars" rel="nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer" style="color: rgb(0, 0, 0); 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text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; background-color: rgb(255, 253, 251); margin: 0px;"><span style="color: rgb(65, 183, 185);"><b>Genome editing, cutting-edge technology for a sustainable agriculture</b></span></p><br><span style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;"><img alt="banner mail" width="498" height="81" data-mce-src="https://psbzim02.psb.ugent.be/home/signature@psb.ugent.be/Briefcase/PUBLIC/footer.png" src="https://psbzim02.psb.ugent.be/home/signature@psb.ugent.be/Briefcase/PUBLIC/footer.png" saveddisplaymode="" style=""></span><br><span style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;">VIB-UGent Center for Plant Systems Biology</span></center><center style="color: rgb(0, 0, 0); font-family: verdana, helvetica, sans-serif; font-size: 9pt;">Ghent University<br>Technologiepark-Zwijnaarde 71<br>9052 Ghent-Belgium<br>Phone: +32(0)9 331 38 00<br><a href="http://www.psb.vib-ugent.be" rel="nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer nofollow noopener noreferrer" target="_blank">https://www.psb.ugent.be/</a></center></div></div><br></div><br><br></div></div></div></div></div><br></div></div></div></div></div></div><br></div><style>/*<![CDATA[*/p.MsoNormal, li.MsoNormal, div.MsoNormal {
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