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New permanent position: drug discovery data scientist, Janssen
by Ceulemans, Hugo [JRDBE] 21 Dec '15

21 Dec '15

Drug discovery data scientist Key words: data sciences, computational biology, bioinformatics, drug discovery Permanent position at Janssen in Beerse Context Within the Discovery Sciences group, which provides advanced technology support to drug discovery projects in Janssen, the Computational Sciences department is responsible for comprehensive analyses of high-dimensional datasets. The position will be opened on the Beerse campus, which is the largest R&D center for small molecules within the entire Janssen group, investing over 1 billion euros each year in R&D. Activities cover the integration of information from the broadest possible spectrum of datasources (chemical structure, microscopy images and omics, ...) to comprehensively infer biological activities of millions of chemical compounds, and to apply these predictions to inform projects. In addition, the team designs and supports the execution of the generation of high-dimensional datasets (from cytometry or various sequencing approaches) from patient-derived material. The team is also responsible for the use of these data for the identification of potential mechanisms of disease and targets of intervention and the subpopulations of patients these mechanisms apply to. Job description In the context of the latter task, the department is opening a permanent position for a drug discovery data scientist, who will focus on the analysis and interpretation of high-dimensional datasets to identify interventional strategies for neurological, cardiovascular and metabolic, infectious, immunological or oncological diseases. The candidate will be responsible for * the translation of questions of disease experts in the therapeutic areas and wet lab colleagues, to a quantitative analysis formulation * the design and execution of targeted analysis approaches to link processed molecular and cellular data at scale to pathophysiological processes or clinical outcome, to produce actionable conclusions and to inform decision making * the development and internalization of rigorous state-of-the-art approaches for integrative data analysis, and build-out and leveraging of collaborations with leading academic and industrial scientific teams in life, computational and data sciences * work with informatics and statistics colleagues to offer the resulting analysis and visualization solutions to the project teams * contributing to the scientific weight of the department by authoring peer-reviewed papers and presenting at relevant conferences Qualifications and skills * PhD in Computational Biology or any related quantitative field with direct exposure to multidisciplinary biology or clinical context with ideally a few years of post-doctoral experience in an academic or industrial setting * demonstrated experience with linking high-dimensional molecular data, to phenotypic or clinical outcomes in constellations that led to hypothesis driven experimental or clinical follow-up * advanced programming and scripting skills that enable the development of functional prototypes * excellent communication, reporting and team interaction skills, self-motivation, proactivity and the ability to work independently If you are interested, please reply with the appropriate documentation to hceulema - at - its - dot - jnj - dot - com.

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bioinformatics Post-doc position for 2 years
by Stephane Rombauts 19 Dec '15

19 Dec '15

Dear. > Comme vous le savez nous sommes toujours à la recherche d’un(e) candidat(e) pour un postDoc en bio-analyse . > Si la personne est étrangère et n’a pas séjourné en France nous pouvons lui proposer un contrat plus long >grace a un financement régional que nous avons obtenu sur le projet . in attachment position in France Roscoff (Bretagne) for a bioinformatics position for 2years if the candidate is currently not living in France. Deadline end of 2015!!! Best regards

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Computational Cancer Biology with GSK
by Lodewyk Wessels 18 Dec '15

18 Dec '15

Computational cancer biology for precision medicine Project outline For an ambitious joint project between the Netherlands Cancer Institute (NKI, Amsterdam, The Netherlands) and Glaxo Smith Kline (Philadelphia, USA) we invite excellent and ambitious postdocs with expertise in computational biology to apply. It is the goal of this international team to study BET and EZH2 inhibitors. More specifically, we will explore the molecular responses to these inhibitors, identify and understand additional mechanisms of acquired and intrinsic resistance and identify markers of sensitivity and resistance to these inhibitors. We will employ public and proprietary data derived from model systems as well as patient data. In addition to chemical profiling data, these data include gene expression, copy number and ChIP-sequencing profiles as well as mutation data. The expected duration of the initial phase of the project is 2 years. The computational biologists will collaborate closely with experimentalists, and there will be ample opportunity to validate hypotheses generated through computational analyses. Requirements Degree in bioinformatics, physics, engineering, computer science or mathematics A strong cancer biology interest and/or background Proficiency in programming languages such as R, Python, Perl. Contact details Please contact Lodewyk Wessels (phone +31 20 512 7987, e-mail: l.wessels(a)nki.nl <mailto:l.wessels@nki.nl>) or Mike McCabe (e-mail: michael.t.mccabe(a)gsk.com <mailto:michael.t.mccabe@gsk.com>). When applying, please ensure you include a CV, list of publications and the names and addresses of at least two persons that can be approached as references. Also see http://ccb.nki.nl/open-positions/ <http://ccb.nki.nl/open-positions/> for further information. Closing date 15 February 2016

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Systems Biology post-doctoral position available: European Institute for Systems Biology and Medicine, Lyon France
by Bertrand 18 Dec '15

18 Dec '15

Dear all, We open a post-doctoral researcher position in Systems Biology and Medicine at CNRS-EISBM in Lyon, France, in relation to the IMI-eTRIKS consortium. The subject is '*Module-based development of disease-specific network reconstructions for data interpretation, disease stratification and biomarker discovery*'. We are looking for highly motivated candidates with a PhD in computational biology, systems biology, bioinfrmatics or equivalent. Experience in pathway reconstruction and familiarity with Systems Biology standards (SBGN, BioPAX, SBML) is desirable. Experience in programming (Java, Python) would also be desirable. The position requires good communication skills in English and involves working in collaboration with eTRIKS partners on translational medicine projects across Europe. More details can be found in the atached document. Please send your CV, application letter and the name of two references to Dr Charles Auffray: jobs(a)eisbm.org, mentionning the reference 'EISBM-12-15-AM'. Don't hesitate to circulate this offer to anyone interested! Best regards, Bertrand De Meulder -- EISBM logo <http://www.eisbm.org> *Bertrand De Meulder Researcher * European Institute for Systems Biology and Medicine Campus Charles Mérieux - Université de Lyon CNRS - UCBL - ENS *E-mail:*bdemeulder@eisbm.org <mailto:bdemeulder@eisbm.org> *Office:* +33(0)4 37 28 74 41 *Office* Université Claude Bernard 3^e étage plot 2 50 Avenue Tony Garnier 69366 Lyon cedex 07 France *Laboratory* LyonBioPôle - Centre d'Infectiologie 2^e étage Bât. Domilyon 321 Avenue Jean Jaurès 69007 Lyon France Follow us : EISBM eisbm.org <http://www.eisbm.org> | Facebook Facebook <http://www.facebook.com/EISBM> | Twitter Twitter <http://twitter.com/EISBM_EU> --- L'absence de virus dans ce courrier électronique a été vérifiée par le logiciel antivirus Avast. https://www.avast.com/antivirus

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Bioinformatics post-doctoral position available: European Institute for Systems Biologi and Medicine, Lyon France
by Bertrand 18 Dec '15

18 Dec '15

Dear all, We open a post-doctoral researcher position in Bioinformatics at CNRS-EISBM in Lyon, France, in relation to the IMI-eTRIKS consortium. The subject is ' *Disease and target-specific knowledge enrichment using disease network models* '. We are looking for highly motivated candidates with a PhD in computational biology, bioinformatics, computer sciences, mathematics, physics or engineering, with a strong basis in programming (Python, Matlab, C/C++, Java, R or similar). Experience of analysis of biological networks is desirable. The position requires good communication skills in English and involves working in collaboration with eTRIKS partners on translational medicine projects across Europe. More details can be found in the atached document. Please send your CV, application letter and the name of two references to Dr Charles Auffray: jobs(a)eisbm.org, mentionning the reference 'EISBM-12-15-MS'. Don't hesitate to circulate this offer to anyone interested! Best regards, Bertrand De Meulder -- EISBM logo <http://www.eisbm.org> *Bertrand De Meulder Researcher * European Institute for Systems Biology and Medicine Campus Charles Mérieux - Université de Lyon CNRS - UCBL - ENS *E-mail:*bdemeulder@eisbm.org <mailto:bdemeulder@eisbm.org> *Office:* +33(0)4 37 28 74 41 *Office* Université Claude Bernard 3^e étage plot 2 50 Avenue Tony Garnier 69366 Lyon cedex 07 France *Laboratory* LyonBioPôle - Centre d'Infectiologie 2^e étage Bât. Domilyon 321 Avenue Jean Jaurès 69007 Lyon France Follow us : EISBM eisbm.org <http://www.eisbm.org> | Facebook Facebook <http://www.facebook.com/EISBM> | Twitter Twitter <http://twitter.com/EISBM_EU> --- L'absence de virus dans ce courrier électronique a été vérifiée par le logiciel antivirus Avast. https://www.avast.com/antivirus

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Computational Biology post-doctoral position available: European Institute for Systems Biology and Medicine, Lyon France
by Bertrand 18 Dec '15

18 Dec '15

Dear all, We open a post-doctoral researcher position in Computational Biology at CNRS-EISBM in Lyon, France, in relation to the IMI-eTRIKS consortium. The subject is 'Contribution to the development of eTRIKS Galaxy tools and workflows for disease stratification and biomarker discovery from single and multiple omics datasets'. We are looking for highly motivated candidates with a PhD in sciences, computational biology, bioinformatics, computer sciences or equivalent, with a strong basis in programming (R and python), experience in omics analysis and excellent IT skills. Good communication skills in English are required, and experience with Big Data computing in a plus. More details can be found in the atached document. Please send your CV, application letter and the name of two references to Dr Charles Auffray: jobs(a)eisbm.org, mentionning the reference 'EISBM-12-15-BDM'. Don't hesitate to circulate this offer to anyone interested! Best regards, Bertrand De Meulder -- EISBM logo <http://www.eisbm.org> *Bertrand De Meulder Researcher * European Institute for Systems Biology and Medicine Campus Charles Mérieux - Université de Lyon CNRS - UCBL - ENS *E-mail:*bdemeulder@eisbm.org <mailto:bdemeulder@eisbm.org> *Office:* +33(0)4 37 28 74 41 *Office* Université Claude Bernard 3^e étage plot 2 50 Avenue Tony Garnier 69366 Lyon cedex 07 France *Laboratory* LyonBioPôle - Centre d'Infectiologie 2^e étage Bât. Domilyon 321 Avenue Jean Jaurès 69007 Lyon France Follow us : EISBM eisbm.org <http://www.eisbm.org> | Facebook Facebook <http://www.facebook.com/EISBM> | Twitter Twitter <http://twitter.com/EISBM_EU> --- L'absence de virus dans ce courrier électronique a été vérifiée par le logiciel antivirus Avast. https://www.avast.com/antivirus

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PhD & Postdoc positions available in Düsseldorf
by Susanne Hermans 18 Dec '15

18 Dec '15

Dear all, At the Computational Pharmaceutical Chemistry group of Prof. Dr. Holger Gohlke, we have 2 postdoc positions and 2 PhD positions available in structural protein bioinformatics. - Applications are invited for two Postdoc positions on the topic of "Identification of and Virtual Screening on Novel Allosteric Sites using Constraint Network Analysis" within an industrial collaboration. The positions are available in spring 2016. - Applications are invited for two PhD student positions on the topic of "Functional state modulation of membrane proteins by dynamic association and dissociation" within a project funded by the German Research Foundation (DFG) (Collaborative Research Center (CRC) 1208). The positions are available 1.1.2016. For more information about the positions and how to apply visit http://cpclab.uni-duesseldorf.de/openings For more information about the group or the Heinrich-Heine University in Düsseldorf please visit http://cpclab.uni-duesseldorf.de/ and http://www.uni-duesseldorf.de/. best regards, Susanne Hermans PhD Student Computational Pharmaceutical Chemistry and Molecular Bioinformatics Institute for Pharmaceutical and Medicinal Chemistry Department of Mathematics and Natural Sciences Heinrich-Heine University Düsseldorf, Germany

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Technology Facilities: Life Sciences Technologies introductory course, 18-21 January 2016, Leiden
by Celia.vanGelder＠radboudumc.nl 17 Dec '15

17 Dec '15

Technology Facilities: Life Sciences Technologies introductory course Date: 18-21 January, 2016 Location: Leiden Course Coordinators: Wilfred van Ijcken (ErasmusMC), Madeleine Nivard (MGC), Merlijn van Rijswijk (DTL) Website, including programme and registration: https://www.boerhaavenascholing.nl/pages/Boerhaave/ActivityDetails?objid=31… More information: Madeleine Nivard (M.J.M.Nivard(a)lumc.nl<mailto:M.J.M.Nivard@lumc.nl>) On 18-21 January 2016, Medical Genetics Centre "South-West Holland" (MGC), DTL Technologies and DTL Learning jointly organise a a course on life sciences technologies. In four days, the participants will get up to speed with the possibilities of genomics and transcriptomics, proteomics, imaging and metabolomics. The teachers are researchers from ErasmusMC, LUMC and Leiden University with lots of hands-on experience in their field.The course is aimed at PhD students and young postdocs who want to get acquainted with the possibilities of different technologies. Note: It is possible to participate all four days but also to choose to follow one, two or three days of your interest. Programme Overview Monday 18 januari 2016: "Genomics & Transcriptomics" Organizers: Dr. W van IJcken, ErasmusMC, Rotterdam en Dr. H.P.J. Buermans, HG, Leiden Tuesday 19 Januari 2016: "Proteomics" Organizers: Dr. J. Demmers, ErasmusMC, Rotterdam, Dr. P. Hensbergen, LUMC, Leiden Wednesday 20 januari 2016: "Imaging" Organizers: Prof. A. B. Houtsmuller (morning) , dr. W.A. van Capellen(morning), Erasmus MC, Rotterdam, Prof. Dr. C. Lowik (afternoon), LUMC, Leiden Thursday 21 januari 2016: "Metabolomics" Organizers: Thomas Hankemeier en Loes Beijersbergen, LACDR, UL Best regards Celia van Gelder Dr. Celia W.G. van Gelder Education Manager BioSB Coordinator Education CMBI Programme Manager Learning DTL/ELIXIR-NL tel. +31613375327 e-mail: Celia.vanGelder(a)radboudumc.nl<mailto:Celia.vanGelder@radboudumc.nl> websites: www.nbic.nl<http://www.nbic.nl/>, www.biosb.nl, www.cmbi.ru.nl<http://www.cmbi.ru.nl/>, www.dtls.nl Postal address: CMBI 260 Radboud University Nijmegen-Medical Centre PO Box 9101 6500 HB Nijmegen The Netherlands Het Radboudumc staat geregistreerd bij de Kamer van Koophandel in het handelsregister onder nummer 41055629. The Radboud university medical center is listed in the Commercial Register of the Chamber of Commerce under file number 41055629.

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Introduction to Next Generation Sequencing; technologies, applications, and data analysis course, 12-15 April 2016
by Sari van Heel - Vauhkala 17 Dec '15

17 Dec '15

Dear Members of BBClist, We would like to draw your attention to an international course that the Research Group Analysis Techniques in Life Science (Avans University of Applied Sciences, Breda, the Netherlands) will be offering in April 2016: Introduction to Next Generation Sequencing; technologies, applications, and data analysis Course date: 12 – 15 April 2016 Registration fee: €1.100,- Website : http://www.alsavans.nl/avans-training-2545.htm The digital registration form is available on the website. Should you have any questions, please do not hesitate to contact us by email at: si.vanheel-vauhkala(a)avans.nl<mailto:si.vanheel-vauhkala@avans.nl> Kind regards, Ms. Sari van Heel-Vauhkala Secretary Research Group Analysis Techniques in Life Science Disclaimer ( http://www.avans.nl/over-avans/e-mail-disclaimer )

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Vacature Hogeschool Leiden
by Stelling, Klaasje 11 Dec '15

11 Dec '15

Geachte heer/mevrouw, Het cluster Techniek van Hogeschool Leiden is op zoek naar inspirerende en onderzoekende "Docent(en)/onderzoeker(s) Bio-Informatica (1,2 fte - 2,0 fte)". Kijk voor meer informatie de bijlage of onze website, http://www.hsleiden.nl/over-hl/werken-bij/vacatures/vacatures Met vriendelijke groet, Klaasje Stelling Adviseur HRM Hogeschool Leiden Afdeling HRM Zernikedreef 11, kamer F2.006/F2.008/F2.013 Postbus 382, 2300 AJ Leiden Mobiel: 06-52781722 Website: www.hsleiden.nl<http://www.hsleiden.nl/> Is het écht nodig deze e-mail te printen? 'Hogeschool Leiden, jouw duurzame ruimte' Op deze e-mail zijn de voorwaarden van toepassing als vermeld op: The following conditions apply to this e-mail: http://www.hsleiden.nl/disclaimer-email

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