Structural Bioinformatics course, 12-16th October 2015 Venue: EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridge UK Course organisers: Gerard Kleywegt (EMBL-EBI), Christine Orengo (UCL) and Tom Hancocks (EMBL-EBI) Full programme and registration details can be found at: http://www.ebi.ac.uk/training/course/structural-bioinformatics Course overview This course will explore bioinformatics data resources and tools that are available for the interpretation and exploitation of biomacromolecular structures, focusing on how best to use structural information to gain the most from it in specific research contexts. This will include investigating the impact of genetics variation on structure, predicting protein structure and function and exploring interactions with other macromolecules as well as with low-MW compounds. Course Audience This course is aimed at researchers who want to learn more about the application of structural information in their work and how to use the bioinformatics resources that are available. No previous experience of structural bioinformatics is required. Syllabus During this course you will learn about: * Public repositories of structural data: Protein Data Bank (PDB) and Electron Microscopy Data Bank (EMDB), and tools to search and analyse information in these repositories from PDBe (Protein Data Bank in Europe) * Computational approaches to structure prediction: ModBase, Rosetta, PHYRE, Interactome 3D * Impact of genetic variation on protein structure: Ensembl VEP, DBSeq, SAAPdb * Protein analysis and classification: Pfam, CATH, SCOP, InterPro, PDBeFold, PDBePISA, ProFunc * Tools and resources for drug discovery: ChEMBL This message sent to you as member of the NSBM mailinglist Het Radboudumc staat geregistreerd bij de Kamer van Koophandel in het handelsregister onder nummer 41055629. The Radboud university medical center is listed in the Commercial Register of the Chamber of Commerce under file number 41055629.