Postdoctoral
Fellow in Cancer Systems Biology
A 3-year
FP7-funded postdoctoral position is available from November 1, 2010 in the
Oncogenomics Laboratory at the Center for Medical Genetics, Ghent University.
Job
description: The candidate will perform gene
expression network analysis and systems biology research aiming to gain
insights into the perturbed signaling in the pediatric peripheral nervous tumor
neuroblastoma. The project is part of a broader ongoing research effort at the
Oncogenomics Laboratory in collaboration with various other research groups in
Europe and worldwide.
The candidate
will be expected to develop and utilize bioinformatics algorithms to interpret
and integrate various comprehensive genomic datasets including mRNA and
miRNA expression data (Affymetrix, RNA-seq) of large unique pediatric tumor
series and similar datasets, ChIP-seq and proteome data from in vitro
model systems with emphasis on protein coding genes and miRNAs implicated in
developmental pathways. Integrated gene regulatory network building will
form the basis for further search for molecular targets for targeted therapies.
This position offers many opportunities for collaboration in a diversity of methodologically
and biologically challenging areas of cancer research and links fundamental
cancer research to translational research with direct potential towards
development of new therapeutic strategies.
Requirements:
The vacancy is a research position within
the field of bioinformatics/computational biology and the research will be
carried out in close collaboration with the involved partners. The ideal
candidate has a PhD degree or equivalent in bioinformatics, computer science,
statistics, physics, or biology and has preferably a strong background in
algorithm development and/or machine learning, and experience with
analyzing high-throughput data.
Employer
information: The laboratory of Prof. F. Speleman (http://medgen.ugent.be/CMGG/) has a
proven track record both in the study of the genetic basis of neuroblastoma and
bioinformatic algorithm development (see selected publications below).
The past years,
our laboratory has received substantial funding including grants from EU and
the Belgian Federal government. We have a young, dynamic and highly
interactive research team. The new postdoctoral fellow will be integrated
in this team and will in particular work very closely and interact with a rapidly
growing group of researchers with bioinformatics skills.
The work is
supported by in-house developed bioinformatic tools and a high level
informatics environment. We support possibilities for further training through
participation in workshops, meetings etc.. Ghent is a beautiful medieval city
and one of the biggest student cities in Belgium with a vivid social and
cultural life (www.visitgent.be).
Salary: The salary will be in accordance with university regulations
for academic personnel at postdoc level depending on the level of
experience (43,022 – 47,989 €).
How to
apply: Applicants should submit a CV, letters of
recommendation of two orevious employers, pdf files of your best papers to
Prof. Frank Speleman (franki.speleman@ugent.be) with email subject
“Postdoctoral application”.
The
Oncogenomics Laboratory
Center for
Medical Genetics Ghent (CMGG) Ghent University Hospital Medical Research
Building (MRB), 2nd floor, room 120.029 De Pintelaan 185, B-9000 Ghent, Belgium
+32 9 332 2451
(phone) | +32 9 332 6549 (fax)