Network Biologists with a keen interest in Integrative Bioinformatics (post doctoral) The Biomolecular Mass Spectrometry and Proteomics Group (Heck-group, www.hecklab.com<http://www.hecklab.com>) at Utrecht University (www.uu.nl<http://www.uu.nl>) the Netherlands is looking for a Network Biologists with a keen interest in Integrative Bioinformatics This person will be able to use and develop tools to analyze, integrate and visualize data obtained primarily by mass spectrometry based proteomics but with the aim to perform integrative analysis using data obtained by siRNA screens, NGS, metabolomics and other post-genome technologies. The projects will primarily be related to stem cell and cancer related research, with a special attention to focus on perturbation in network biology induced by gene mutations and small molecule drugs. We expect the candidate to be experienced in relevant bioinformatics tools such as Cytoscape, PathVisio (or other pathway analysis tools) and [R]. Also a strong background in bio-statistics and programming (e.g. in Java, Perl, Python) is an advantage. Ideally also experience with MS-based proteomics data is available. These capabilities should all be clear from your CV, your PhD research and publication list. The person hired will be deeply involved in the programs of the Netherlands Roadmap program “Proteins@Work” (www.proteinsatwork.nl<http://www.proteinsatwork.nl>) and the Gravity Program “CGC.NL” (www.cancergenomics.nl<http://www.cancergenomics.nl>), and be imbedded within the core proteomics facility in Utrecht (www.netherlandsproteomicscentre.nl<http://www.netherlandsproteomicscentre.nl>). We will be able to offer a three years position at a post-doctoral level, being appointed at Utrecht University, Science Faculty. For information please contact prof. dr. Albert J.R. Heck (cgc.nl.networkbiologist@gmail.com<mailto:cgc.nl.networkbiologist@gmail.com>) In your application include a CV, two letters of recommendation and a motivation. You can apply on our website by following this link: http://bioms.chem.uu.nl/jobs/network-biologists-with-a-keen-interest-in-inte... Deadline for applications is January 31st 2014. Related references Next-generation proteomics: towards an integrative view of proteome dynamics.<http://www.ncbi.nlm.nih.gov/pubmed/23207911>Altelaar AF, Munoz J, Heck AJR. Nat Rev Genet. 14 (2013) 35-48. doi: 10.1038/nrg3356. The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers.<http://www.ncbi.nlm.nih.gov/pubmed/22692129> Muñoz J, et al. Embo J. 31 (2012):3079-3091. doi: 10.1038/emboj.2012.166. The quantitative proteomes of human-induced pluripotent stem cells and embryonic stem cells.<http://www.ncbi.nlm.nih.gov/pubmed/22108792> Muñoz J, Low TY, Kok YJ, Chin A, Frese CK, Ding V, Choo A, Heck AJR. Mol Syst Biol. 7 (2011) 550. doi: 10.1038/msb.2011.84. Interrogating cAMP-dependent Kinase Signaling in Jurkat T Cells via a Protein Kinase A Targeted Immune-precipitation Phosphoproteomics Approach. Giansanti P. et al. Mol Cell Proteomics. 12 (2013) 3350-9. Quantitative and Qualitative Proteome Characteristics Extracted from In-Depth Integrated Genomics and Proteomics Analysis. Low TY et. al. Cell Reports 2013. doi: S2211-1247(13)00640-2. 10.1016/j.celrep.2013.10.04 =========================== Dr Ir. Bas van Breukelen Assistant Professor Biomolecular Mass Spectrometry and Proteomics Group Utrecht University Padualaan 8, 3584 CH, Utrecht The Netherlands ----------------------------------------------- E: b.vanbreukelen@uu.nl<mailto:b.vanbreukelen@uu.nl> T: +31(0)30 2539761 M:+31(0)6 42222520 Skype: b.vanbreukelen W: http://www.hecklab.com ===========================