Computational modeling and simulation are emerging as important tools to answer the age-old question in biology:
How do cells form tissues?
While modern microscopy and bio-image informatics are generating quantitative data on tissue formation at unprecedented rates, computational models are increasingly necessary to interpret these data, test biological
hypotheses and ultimately provide a mechanistic understanding of the molecular and cellular mechanisms that drive the morpho-dynamics of multicellular systems.
In recent years, computational models of multicellular systemshave been successfully applied in a wide range of fields including animal and plant morphogenesis, stem cell biology, regeneration, vascular development and tissue engineering. Despite notable differences in the application and validation of models, a common set of approaches has emerged to elucidate the logic of the biochemical and biomechanical interactions between cells.
The workshop “Computing a tissue” present the state-of-the-art in computational modeling of multicellular systems. It highlights landmark studies of multicellular modeling across a range of biological fields, discusses the strengths and challenges of various modeling approaches and examines the current and upcoming computational methods and tools.
All students and researchers interested in the computational modeling of multicellular systems are welcome.
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