Vacancy for a PhD or Postdoc in Multi-scale Analysis of Genomics Data at the Delft University of Technology Location - Delft University of Technology, Delft, The Netherlands Job Link - http://www.academictransfer.com/employer/TUD/vacancy/5151/lang/en/ Job description - This project aims to exploit scale-space theory for the analysis of high-throughput genomics data to delineate the complex interplay among biological elements of molecular processes that takes place in living systems. The notion of scale plays an important role in how we observe our environment. For instance, considering a tree from a distance of a light-year or a nanometre is meaningless, but would make sense at a distance of a few metres. Clearly, objects only exist as meaningful entities across a certain range of scales. In the field of machine vision, it has been argued that the only appropriate approach to this problem is to analyse data at all scales simultaneously. This has led to the scale-space theory, which provides a framework for multi-scale representation of images or other signals. We will explore scale-space representations of various sources of genomics data and investigate how we can employ these representations to benefit follow-up analyses, e.g. classification or interaction inference. The challenge will be to develop innovative methodologies that can exploit available genomics data at multiple scales simultaneously rather than at a single scale, and to explore possible applications of these methods using datasets generated at the Kluyver Centre for Genomics of Industrial Fermentation, the Netherlands Cancer Institute (NKI) and publicly available datasets.