A postdoctoral research position in the De Rybel lab (VIB) in the
area of single cell transcriptomics in crop plants is available.
This position is a close collaboration between the De Rybel and
Saeys labs at VIB in collaboration with BASF as industrial partner
in the framework of an approved VLAIO project. The successful
candidate will adapt existing wet lab single cell transcriptomics
methodologies to crop plant species and initiate statistical
analysis of this data. As such, this position entails the
integration of both wet lab and dry lab into one collaborative
project.
About the Partners
The De Rybel lab at the VIB‐UGent Center for Plant Systems Biology
(PSB) has a key interest in understanding cell division
orientation in plants and how this process contributes to vascular
proliferation. The lab has a long-standing expertise in using bulk
RNA-sequencing to uncover transcriptional networks during plant
developmental processes. More recently, a strong investment was
made to establish single cell RNA-seq (scRNA-seq) workflows to
further increase resolution at spatial and temporal level. In this
case, the wet-lab expertise was developed by the De Rybel lab,
while the bio-infomatics expertise and all data analysis was
optimised in the Saeys lab.
The Saeys lab at the VIB-UGent Center for Inflammation Research
(IRC) studies the design and application of data mining and
machine learning techniques for biomedical applications. The lab
is renowned for its research on single-cell technologies,
including flow and mass cytometry, single-cell RNA sequencing, and
is currently pioneering novel single-cell technologies including
spatial transcriptomics and single-cell multi-omics (e.g.
CITE-seq).
The BASF Innovation Center in Gent aims to deliver innovative
solutions for BASFs seed business by developing valuable traits
for various crops through biotechnology solutions and modern
breeding techniques. The activities of the Innovation Center cover
all aspects involved with the R&D process, from the initial
stages of research to life cycle management, or as we call it,
from the lab to the field. The Innovation Center employs a
workforce of approximately 400 from 20 different countries at
state-of-the-art laboratories space for plant biotechnology
research in Zwijnaarde and greenhouse and breeding installations
in Astene, Zwijnaarde, and Bottelare.
Your project
Embedded in the De Rybel lab at VIB and in close collaboration
with the Saeys lab at VIB and BASF as industrial partner, you will
support the implementation, analysis and ongoing development of
single cell transcriptome data-sets in the context of plant
biotechnology. As a true go-between these collaborative groups,
you will work at the intersection between the experimental
scientists and the computational scientists.
You will be involved in the wet lab data generation pipeline with
the De Rybel lab, BASF and VIB core facilities to further optimize
the existing workflows. You will be involved in the dry lab data
analysis pipeline with the Saeys lab and BASF to establish and
optimise the bio-informatic workflows.
Profile
We offer
How to apply?
For more information contact Bert De Rybel. Please complete the online
application procedure and include a detailed CV incl. list
of publications, a motivation letter and the contact information
of three referees.
-- =============================================================================== Prof. dr. Yvan Saeys VIB Group Leader Data mining and modeling for biomedicine UGent Department of Applied Mathematics, Computer Science and Statistics Krijgslaan 281, S9, B-9000 Gent Inflammation Research Center, a VIB-UGent Department Technologiepark-Zwijnaarde 71 , B-9052 Zwijnaarde , Belgium Tel : +32(0)9 331 37 40 Fax : +32(0)9 221 76 73 Mailto: yvan.saeys@ugent.be http://www.dambi.ugent.be ===============================================================================