
Dear all We have an exciting postdoc position available in cancer bioinformatics, that should be filled in as soon as possible. *Job description* The postdoc will be part of a joint international effort to implement personalized immunotherapy, targeting unique tumor associated mutations in patients. This is an exciting position at the crossroad of the blooming field of cancer genomics, and immunological bioinformatics. The postdoc will be working on two main projects: 1) evaluation and further development of existing models to predict the likelihood that a presented tumor mutation (in the form of a peptide-MHC complex) is recognized by the patient’s immune system, and 2) based on the primary sequence information of T cell receptors, predict their most likely ligands (e.g., mutations found in the individual patients). These innovative and ambitious projects will be performed in close collaboration with Prof. Ton Schumacher from Dutch Cancer Institute (NKI). The position is part of the EU Horizon2020 project called "APERIM: Advanced bioinformatics platform for PERsonalised cancer Immunotherapy” (H2020-PHC-2014), consisting of eight academic partners and three companies. *Qualifications* We are looking for a bioinformatician at the postdoc level with a keen interest in immunology and/or cancer. The position can be converted into a PhD student in case we have an excellent candidate. Applications from cancer immunologists with some computational experience are highly welcome. * Offer* The candidate is offered a full-time position for three years.The salary is supplemented with a holiday bonus of 8% and an end-of-year bonus of 8,3% per year. In addition we offer: a pension scheme, a partially paid parental leave, flexible employment conditions <http://www.uu.nl/EN/informationfor/jobseekers/Working-for-Utrecht-University/terms-of-employment/Pages/default.aspx>. Conditions are based on the Collective Labour Agreement Dutch Universities. The research group will provide the candidate with necessary support on all aspects of the project. *About the organisation* Utrecht University <http://www.uu.nl/en> has great ambitions for its teaching quality and study success rates. This also applies to its clear research profiles which are centred around four themes: Dynamics of Youth, Institutions, Life Sciences and Sustainability. Utrecht University plays a prominent role in our society and contributes to finding the answers to topical and future societal issues. The Faculty of Science <http://www.uu.nl/en/organisation/faculty-of-science> consists of six departments: Biology, Pharmaceutical Sciences, Information and Computing Sciences, Physics and Astronomy, Chemistry and Mathematics. The Faculty is home to 3500 students and nearly 2000 staff and is internationally renowned for the quality of its research. The Faculty's academic programmes reflect developments in today's society. The theoretical biology and bioinformatics <http://tbb.bio.uu.nl/> (TBB) group at the Biology department of Utrecht University employs computational and mathematical models and bioinformatics to perform fundamental biological research in a variety of biological disciplines, and part of the group is specialized in immunology (Prof. Rob de Boer and Dr. Can Kesmir). We have long a standing expertise in modeling the immune system and in applying bioinformatics (mainly data-driven methods) to predict the specificity of the immune responses. The group is part of the Institute of Biodynamics and Biocomplexity <http://www.ibb-uu.nl/> (IBB <http://www.ibb-uu.nl/>), embedded in one of the largest Biology departments in the Netherlands (>200 new students per year). We are part of the Utrecht Center for Quantitative Immunology <http://tbb.bio.uu.nl/ucqi>(UCQI <http://tbb.bio.uu.nl/ucqi>), which brings together an experienced collaborative team of immunologists, bioinformaticians, and mathematical modelers. This unique position allows daily collaboration with wet lab immunologists and biologists. The group teaches modeling and bioinformatics to biology students at the bachelor and master level. PhD students in the group have diverse backgrounds ranging from biology, physics to mathematics, and typically half of them are from abroad. The IBB focuses on molecular life sciences, and is collaborating with other departments of the Faculty of Science, the Faculty of Medicine, and the Hubrecht Institute in Utrecht. UCQI is a joint effort between Utrecht University and the Utrecht Medical Center. *How to apply?* Application deadline is 1st of July. Please use the following link to apply: https://lnkd.in/dPDXR_7