Dear all, We're looking for a PhD student in biofinformatics at the department of Human Genetics and the Centre for Molecular and Biomolecular Informatics, Radboud university medical centre Nijmegen. Job description Project title: A holistic approach to the analysis of genetic variation in patients. Interpretation of the thousands of single nucleotide variants identified in a single individual is one of the most profound challenges in genetics today, both from a research as well as from a diagnostic perspective. This project will combine the strengths of the CMBI on protein structures together with the knowledge on genome-wide variation from the genetics department to develop novel bioinformatic methods that improve the interpretation of genomic variation in patients. The position is that of a shared PhD student between the CMBI and the department of human genetics. See also http://www2.cmbi.ru.nl/ and http://genomicdisorders.nl Key words: Bioinformatics, genomics, genetic variation, intellectual disability Profile We are looking for a bioinformatics scientist with a strong drive to pursue a carrier in science, and the ability to work in a team. A strong background in computer science and programming is required. Some background in genetics is preferred as well as experience with statistical techniques and machine learning techniques. Organization The protein structure bioinformatics group from Prof. Vriend is part of the Centre for Molecular and Biomolecular Informatics and located within the Radboud Institute for Molecular Life Sciences. The department of Human Genetics is one of the largest human genetics departments in Europe performing both high quality research and patient care. The translational genomics group of Prof. Veltman consists of about 20 people with a background in genetics and bioinformatics and applies novel genomic technologies for basic research as well as patient care. We regularly publish in high-ranking journals. Comments and contact information Include your curriculum vitae, description of research experience and names and addresses of 2 references in your application. For more information you can contact Dr. Christian Gilissen, christian.gilissen@radboudumc.nl<mailto:christian.gilissen@radboudumc.nl>, +31 24 36 68940, Prof. Gert Vriend, vriend@cmbi.ru.nl<mailto:G.Vriend@cmbi.ru.nl> , +31 24 3619521, or Prof. Joris Veltman joris.veltman@radboudumc.nl<mailto:joris.veltman@radboudumc.nl> Het Radboudumc staat geregistreerd bij de Kamer van Koophandel in het handelsregister onder nummer 41055629. The Radboud university medical center is listed in the Commercial Register of the Chamber of Commerce under file number 41055629.