The Maastricht Centre for Systems Biology (MaCSBio) is now hiring!!! The 6 PhD-candidate and 6 postdoc positions are online at http://macsbio.maastrichtuniversity.nl/current-vacancies-0 and on Academic Transfer. Maastricht University, The Netherlands, is looking for several PhD candidates and postdocs who will work on the integration of biological data coming from different empirical domains using mathematical multi-scale modelling approaches. This research will occur within two highly integrated research lines in the new Maastricht Centre for Systems Biology (MaCSBio). The centre, which is a joint activity of three Faculties, will offer a dynamic, challenging environment with high profile multidisciplinary research. We are looking for candidates who are specialists in the approaches needed and who have the ambition and the competences to think and work outside the usual disciplinary boxes. Description research lines: Research line 1: SYStems biology approach TOwards targeted Personalised Prevention of chronic diseases in the 'obese system' (SYSTOPP) By studying the 'obese system', we aim to improve our mechanistic insight into the development of chronic diseases, and to identify new strategies for prevention and treatment based on personalised risk profiles for obese people. We will focus on data- and knowledge-driven approaches to integrate and mathematically model multi-omics data with phenotypic continuous traits and disease states, in the context of interacting environmental factors. We will use the large body of human data and samples available in Maastricht. Research line 2: A systems biology approach to model experience and disease-induced modifications in NEUral and GENetic NETworks (NeuGenNet) This multidisciplinary research programme has the overall goal of achieving new insights into the processes of normal and abnormal experience-induced modifications in brain and genetic networks, using mathematical tools and modelling approaches to bridge research domains and spatial scales of inquiry. The start-up of the programme will focus on advancing dynamic systems theories for modelling complex biological networks and applying these models to study: 1) the neural mechanisms of experience-induced changes in healthy brain networks and cognitive processes and 2) the genomic mechanisms underlying disease-induced changes in these networks and processes. [cid:image001.jpg@01CFE4A8.DE3297D0] Ilja C.W. Arts, PhD Professor of Molecular Epidemiology of Chronic Diseases Dept. of Epidemiology ilja.arts@maastrichtuniversity.nl <mailto:ilja.arts@maastrichtuniversity.nl> www.maastrichtuniversity.nl<http://www.maastrichtuniversity.nl/> macsbio.maastrichtuniversity.nl<http://macsbio.maastrichtuniversity.nl/> www.M2E2.nl<http://www.m2e2.nl/> Peter Debyeplein 1, 6229 HA, Maastricht P.O. Box 616, 6200 MD Maastricht, The Netherlands T +31 43 3882971 F +31 43 3884128 M + 31 6 15623990 [cid:image002.jpg@01CFE4A8.DE3297D0] For more information: http://macsbio.maastrichtuniversity.nl/