Dear all, You are cordially invited to join us for a mini-symposium on Thursday 19th February from 11:00 hours at VU University Amsterdam. For catering, your registration is required but participation is free. Please register here before 17 February: http://www.formdesk.com/vuamsterdam/data_crunch_mini_symp The detailed agenda is given below. Best regards, Medicinal Chemistry VU University Amsterdam --- Data Crunching for Medicinal Chemistry and Life Sciences Mini-symposium on Thursday 19th February in lecture theater WN-F123, De Boelelaan 1085, 1081HV Amsterdam, The Netherlands 11:00 Chair: Iwan de Esch (Division Medicinal Chemistry, VU University Amsterdam) 11:05 Translating biological and chemical data into structure-based protein-ligand interaction prediction Chris de Graaf (Division Medicinal Chemistry, VU University Amsterdam) 11:30 Competitive inhibitors of receptor tyrosine kinases: Rational design, synthesis and in vivo evaluation Didier Rognan (CNRS/Universite de Strasbourg, FR) 12:00 High End StaR-Based GPCR Ligand Design Andrea Bortolato (Heptares Therapeutics, UK) 12:30 Lunch & Networking 13:15 Data-driven medicinal chemistry in the era of big data Scott Lusher (Netherlands eScience Center) 13:45 Explaining Disease Using Big Data: How Valid Is Your Pathway? Jaap Heringa (Centre for Integrative Bioinformatics, VU University Amsterdam) 14:15 Closing remarks --- At 15.45 Albert Kooistra (Medicinal Chemistry, VU University Amsterdam) will defend his PhD thesis entitled "In silico Medicinal Chemistry. Investigating GPCRs: key regulators of signal transduction and cell function", in the Aula of VU University Amsterdam. [cid:06f41657-a295-4e4b-be0a-c53a0cd26ab8@umcn.nl] Het Radboudumc staat geregistreerd bij de Kamer van Koophandel in het handelsregister onder nummer 41055629. The Radboud university medical center is listed in the Commercial Register of the Chamber of Commerce under file number 41055629.