Dear colleagues, Grab your chance to join the upcoming BioSB course, there are still some spots available! Integrated Modeling and Optimization<https://www.dtls.nl/courses/integrated-modeling-and-optimization-fundamental/> Wageningen, 11 - 15 December 2023 In validating models one always meet with the need to fit models to data. So, the parameters that are present in any realistic model have to be chosen based on comparison of model predictions with data. In this matching process optimization techniques are indispensable. That’s why a considerable part of this course is spent on getting you acquainted with the optimization techniques that are nowadays available and widely used. Numerical optimization also is the basis for so-called flux balance analysis (FBA), commonly used to study large metabolic networks. This type of models and their analysis and simulation is also introduced in the course. Target audience The course is aimed at PhD students with a background in bioinformatics, systems biology, computer science or a related field, and life sciences. Participants from the private sector are also welcome. A working knowledge of mathematics, especially differential equations, is recommendable, but we will distribute preparation material to be studied by students missing the required background. Furthermore, at the start we offer a math refresher to help those participants who are not (yet) involved in modelling on a daily basis. More information: click here<https://www.dtls.nl/courses/integrated-modeling-and-optimization-fundamental/>. Registration <https://www.aanmelder.nl/integrated_modeling/subscribe> We look forward to welcoming you. Kind regards, Petra Aarnoutse Community manager BioSB [cid:part1.gtMf3b8Y.pGBav90s@health-RI.nl]