PhD position: Haplotyping in polyploid crops
We have an exciting opportunity for an enthusiastic PhD student to develop new methodology for haplotyping genomes of polyploid crops, using novel genotyping-by-sequencing approaches. We are looking for an ambitious PhD student with an MSc degree in bioinformatics, computer sciences, statistics, biotechnology, biology or plant sciences. The PhD project 'Haplotyping in polyploid crops using genetics, genomics and bioinformatics' aims at solving important questions in crops like potato, leek, rose, chrysanthemum, that have four or six copies of a genome: what is the composition (haplotype) of each of the underlying genomes, both locally (gene level) and over larger distances (chromosome level)? Can we distinguish different dosages of haplotypes? Can we characterize plants in terms of haplotype composition? Can we relate observed haplotypes to variation in phenotypic traits? In this project, the goal is to develop statistical, genetics and bioinformatics tools for novel genotyping-by-sequencing (GBS) approaches for polyploid crops. The project will deliver effective strategies for haplotyping in polyploid crops, faster discovery of candidate genes and of their allelic variants for traits of interest to plant breeders. It is a collaborative initiative of the Bioinformatics and Plant Breeding chair groups at Wageningen University. You will work in close cooperation with other PhD students and researchers involved in related projects on the development of a genetic analysis pipeline for polyploid crops and novel sequencing strategies for polyploid genomes. More information about the position, the research groups involved, and a possibility to apply for this position can be found at: http://www.wageningenur.nl/en/Education-Programmes/PhD-Programme/PhD-Vacanci... Interested candidates can apply up to September 15, 2014 through the above-mentioned website. Dr. Chris Maliepaard (Quantitative aspects of Plant Breeding) Prof. Dick de Ridder (Bioinformatics) Wageningen University The Netherlands
In the Plant Sciences Group of Wageningen University, there is an exciting opportunity for an enthusiastic PhD student to develop integrative models of interactions between infectants and plant hosts, in particular the late blight pathogen (Phytophthora infestans) and tomato. As infectious plant diseases form a major threat to food security and sustainable food production, such models are highly valuable tools in the quest to combat infections. The data required for the model is obtained using a unique "in vitro infection system" developed in-house, allowing to measure transcriptome, proteome and metabolome of both the individual players and their interactions. The project asks for the combination of these rich -omics data sets with available genome-scale data of host and pathogen for integrative analyses, involving the reconstruction of metabolic networks and physical protein interaction networks, both within and between pathogen and host. This will result in a high-level model of the molecular events at the interface between host and pathogen that can then be explored to formulate testable hypotheses on key molecules or interactions and may ultimately provide leads for innovative control strategies. We are looking for an ambitious candidate with an MSc degree in bioinformatics, computational biology, systems biology, genomics or a related area. A proven proficiency in the bioinformatics analysis of large genomics data sets is required, affinity with host-microbe interactions and plant or microbial genomics is considered an advantage. You will be part of a team that includes 'wet lab' scientists from the Laboratory of Phytopathology with ample experience on Phytophthora pathosystems and computational scientists from the Bioinformatics group, experts in data integration and modelling. The deadline for application is November 15, 2014. Additional information can be found on our website, http://www.wageningenur.nl/en/Jobs/Vacancies/Show/PhD-position-Deducing-a-ph... If you have questions about this position, please contact prof. Dick de Ridder (dick.deridder@wur.nl, tel. +31 317 484 074) or prof. Francine Govers (francine.govers@wur.nl, tel. +31 317 483 138. For information on the selection procedure, please consult mrs. Dorien Wissink (dorien.wissink@wur.nl). Applications can only be submitted online, through the website given above; please do not mail material directly to the persons above.
participants (1)
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Ridder, Dick de