*** CALL FOR PARTICIPATION *** 4th Integrative Bioinformatics Workshop September 10-12, 2007 University of Gent, Belgium *** REGISTER ONLINE *** workshop web: http://www.rothamsted.bbsrc.ac.uk/bab/conf/ib07/ IMPORTANT DATES August 13: Registration for participation deadline August 27: Poster submission deadline KEYNOTE TALKS Prof Carole Goble, School of Computer Science, University of Manchester, UK "myExperiment: A MySpace for the Self-serving Bioinformatician" Prof Søren Brunak, BioCentrum-DTU, Technical University of Denmark "Integrating data for interactome analysis across organisms" Dr David Searls, Senior Vice President, Informatics, GlaxoSmithKline Pharmaceuticals, USA "Integrative Drug Discovery" Dr Luis Serrano, EMBL, Heidelberg, Germany "Structure-based prediction of protein-protein and protein-DNA interactions" Sponsored by the European Science Foundation PROGRAMME Monday 10th September 2007 11:30 Registration desk opens 12:30 Lunch (buffet style) 13:10 Welcome followed by some administrivia Jacob Koehler and Martin Kuiper 13:20 keynote Understanding interactomes by data integration Søren Brunak (Technical University of Denmark) Session 1 Database Integration and Integrative Databases 14:00 A Methodology for Comparative Functional Genomics Alam, I; Cornell, M; Soanes, D M; Hedeler, C; Wong, H M; Rattray, M; Hubbard, S J; Talbot, N J; Oliver, S J; Paton, N W 14:25 Community-based Linking of Biological Network Resources: Databases, Formats and Tools Telgkamp, M.; Koschützki, D.; Schwöbbermeyer, H.; Schreiber, F. 14:50 Defining Mapping Mashups with BioXMash Hunt, E; Boesinger, C; Jakubowska, J; Norrie, M 15:15 Data Linkage Graph: computation, querying and knowledge discovery of life science database networks Lange, M.; Himmelbach, A.; Schweizer, P.; Scholz, U. 15:40 Coffee break 16:00 Exploring PSI-MI XML Collections Using DescribeX Samavi, R.; Consens, M.P.; Khatchadourian, C.; Topaloglou, T. 16:25 VINEdb: a data warehouse for integration and interactive exploration of life science data Hariharaputran, S; Töpel, T; Brockschmidt, B; Hofestädt, R 16:50 Integration of Heterogeneous Cis-Antisense Gene Pair Data Sets Mapping onto the Human Genome Orlov, YL; Zhou, J; Kuznetzov, VA 17:15 Exchange of integrated datasets - the OXL format Taubert, J; Sieren, KP; Hindle, M; Hoekman, B; Winnenburg, R; Philippi, S; Rawlings, C; Köhler, J. 17:40 Poster Session 19:30 BeerFest Tuesday 11th September 2007 10:00 keynote myExperiment: A MySpace for the Self-serving Bioinformatician? Carole Goble (University of manchester, UK) Session 2 Integrative Systems Biology I 10:40 Integration of constraints documented in SBML, SBO, and the SBML Manual facilitates validation of biological models Lister, AL; Pocock, M; Wipat, A 11:05 Coffee break 11:20 Stochastic effects in a compartmental model for mitotic checkpoint regulation Ibrahim, B; Dittrich, P; Diekmann, S; Schmitt, E 11:45 Reactome: An integrated expert model of human molecular processes and access toolkit de Bono, B 12:10 A High-Level Petri Net Framework for Genetic Regulatory Networks Banks, R; Steggles, LJ 12:35 Lunch (buffet style) 13:30 keynote Structures in systems biology Pedro Beltrao1, Christina Kiel and Luis Serrano (CRG-EMBL Systems Biology Unit, Spain) Session 3 Integrative Systems Biology II 14:10 From MIN meta-model to ordinary differential equations Yartseva, A; Devillers, R; Klaudel, H; Kepes, F 14:35 GeneBrowser: a novel approach for integration and functional classification of microarray data Arrais, J.P.; Santos, B.; Fernandes, J.; Carreto, L.; Santos, M.A.S.; Oliveira, J.L. 14:50 Functional and Transcriptional Coherency of Modules in the Human Protein Interaction Network Futschik, ME; Chaurasia, G; Russ, J; Herzel, H 15:15 Coffee break Session 4 Data Analysis and Interpretation 15:45 Mining for Single Nucleotide Polymorphisms in Expressed Sequence Tags Souche, E.L.; Hellemans, B.; Van Houdt, J.K.J.; Canario, A.; Klages, S.; Reinhardt, R.; Volckaert, F.A.M. 16:10 Mapping protein information to disease terminologies Mottaz, A.; Yip, Y.L.; Ruch, P.; Veuthey, A.-L. 16:35 Developmental Anatomy Ontology of Zebrafish -an Integrative semantic framework Belmamoune, M.; Verbeek, F.J. 17:00 CIDA: An integrated software for the design, characterisation and global comparison of microarrays Khalid, S; Khan, M; Symonds, A; Wang, P; Liu, X; Li, S 17:25 IMS2 -- An integrated medical software system for early lung cancer detection using ion mobility spectrometry data of human breath Baumbach, J; Bunkowski, A; Lange, S; Oberwahrenbrock, T; Kleinboelting, N; Rahmann, S; Baumbach, JI 17:50 Poster session 19:30 Conference dinner Wednesday 12th September 2007 10:00 keynote Integrative Drug Discovery David Searls (GlaxoSmithKline Pharmaceuticals, USA) Session 5 Data Classification 10:40 Supervised classification of combined copy number and gene expression data Riccadonna, S; Jurman, G; Merler, S; Paoli, S; Quattrone, A; Furlanello, C 11:05 Prediction of protein-protein interactions using one-class classification methods and integrating diverse biological data Reyes, J. A.; Gilbert, D. R. 11:30 Coffee break 11:50 Monophyletic clustering and characterization of protein families Zhang, J.; Zhao, Z.; Evershed, J.; Li, G. 12:15 A Tool for Evaluating Strategies for Grouping of Biological Data Jakoniene, V; Lambrix, P 12:40 Closing remarks 12:50 Lunch (buffet style) and Depart ORGANISING COMMITTEE Ralf Hofestädt, Bielefeld University, Germany Jacob Koehler, Rothamsted Research, UK Martin Kuiper, VIB, University of Gent, Belgium Paul Verrier, Rothamsted Research, UK CONTACT Karen Morris, BAB Division, Rothamsted Research, West Common, Harpenden, Herts. AL5 2JQ, UK email: karen.morris(at)bbsrc.ac.uk tel: +44 (0)1582 763133 extension 2813 fax: +44 (0)1582 467907