April 2007 - beg-evodevo@psb.ugent.be

[Beg-evodevo] ScienceDirect - Trends in Genetics : The ambiguous boundary between genes and pseudogenes: the dead rise up, or do they?
by Lieven Sterck 25 Apr '07

25 Apr '07

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCY-4NBR8G5-1&_u…

1 0

[Beg-evodevo] Patterns of internal gene duplication in the course of metazoan evolution
by Stefanie De Bodt 23 Apr '07

23 Apr '07

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&dopt=Abstract&db… Internal duplication can enhance the function of a gene or provide raw material for the emergence of a new function in a gene. Therefore, it is interesting to see whether the frequency of internal duplication has increased during metazoan evolution. The growing number of sequenced eukaryotic genomes provides an excellent opportunity to study the change in the pattern of internal duplication in the course of metazoan evolution. We studied repeated segments in proteins in the proteomes of 11 eukaryotes. We found that the frequency of internal duplication in Caenorhabditis elegans and Drosophila melanogaster (two protostomes) is higher than that in fungi but lower than that in chordates. Moreover, the frequencies of internal duplication for the chordates studied are largely similar. We classified orthologous proteins of chordates into three antiquity groups and found that more recently derived proteins in the metazoan lineage have higher repetitiveness than older ones. Our analysis suggests that lineage-specific internal duplication in protein evolution increases with organismal complexity before the emergence of chordates but not so afterward. Proteins with repeated regions might have been preferred before the protostome-chordate split. This finding supports the suggestion that exon-shuffling occurred more frequently after the first multicellular organism appeared and might have contributed to the metazoan radiation. -- ================================================================== Stefanie De Bodt, PhD VIB Department of Plant Systems Biology, UGent Bioinformatics and Evolutionary Genomics Technologiepark 927 B-9052 Gent Belgium Tel: 32 (0)9 3313692 Website: http://bioinformatics.psb.ugent.be ==================================================================

1 0

[Beg-evodevo] Entrez PubMed
by Yves Van de Peer 16 Apr '07

16 Apr '07

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&dopt=Abstract&db…

1 0

[Beg-evodevo] Vanavond, Terzake, 20u: Creationisme vs. Darwinisme
by Cindy Martens 09 Apr '07

09 Apr '07

-- ========================================================= Cindy Martens VIB DEPARTMENT OF PLANT SYSTEMS BIOLOGY, UGent Bioinformatics and Evolutionary Genomics Technologiepark 927 B-9052 Gent Belgium Tel: +32 (0)9 331 38 22 Fax: +32 (0)9 331 38 09 E-mail: cindy.martens(a)psb.ugent.be Website: http://www.psb.ugent.be/bioinformatics =========================================================

1 0

[Beg-evodevo] Entrez PubMed
by Yves Van de Peer 08 Apr '07

08 Apr '07

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&dopt=Abstract&db…

1 0