A phylostratigraphy approach to uncover the genomic history of major adaptations in metazoan lineages

Tomislav Domazet-Lošo, Josip Brajković and Diethard Tautz

Macroevolutionary trends traditionally are studied by fossil analysis, comparative morphology or evo-devo approaches. With the availability of genome sequences and associated data from an increasing diversity of taxa, it is now possible to add an additional level of analysis: genomic phylostratigraphy. As an example of this approach, we use a phylogenetic framework and embryo expression data from Drosophila to show that grouping genes by their phylogenetic origin can uncover footprints of important adaptive events in evolution.

-- 
==================================================================
Cindy Martens

VIB Department of Plant Systems Biology, Ghent University
Technologiepark 927, 9052 Gent, BELGIUM
Tel: +32 (0)9 331 38 22
Fax: +32 (0)9 331 38 09
E-mail: cindy.martens@psb.ugent.be
Website: http://bioinformatics.psb.ugent.be/
==================================================================