Reciprocal gene loss between Tetraodon and zebrafish after whole genome duplication in their ancestor

Marie Sémon and Kenneth H. Wolfe

The whole genome duplication that occurred in ray-finned fish coincided with the radiation of teleost species; consequently, these two phenomena have often been linked. Using the Tetraodon and zebrafish complete genome sequences, we tested a molecular hypothesis that can relate whole genome duplication to speciation in teleosts. We estimate that thousands of genes that remained duplicated when Tetraodon and zebrafish diverged underwent reciprocal loss subsequently in these two species, probably contributing to reproductive isolation between them.

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Cindy Martens                                  Tel:32 (0)9 3313822
DEPARTMENT OF PLANT SYSTEMS BIOLOGY            Fax:32 (0)9 3313809
GHENT UNIVERSITY/VIB,    Technology Park 927, B-9052 Gent, Belgium
Vlaams Interuniversitair Instituut voor Biotechnologie         VIB
mailto:cimar@psb.ugent.be
http://www.psb.ugent.be/bioinformatics
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