fyi
http://genefriends.org/
GeneFriends is a functional genomics tool aimed at biologists and
clinicians. It is based on a gene co-expression map that describes which
genes tend to be activated (increase in expression) and deactivated
(decrease in expression) simultaneously in a large number of microarray
datasets. Because the microarray datasets come from a wide range of
conditions, the co-expression map reflects which genes in general tend
to be activated simultaneously and are thus under similar
transcriptional regulation. This information can be used statistically,
using a guilt-by-association approach, to identify and prioritize novel
candidate genes involved in biological processes and complex diseases
for which a seed list of genes associated with that disease or process
is available. It can also be used to gain insights on genes of unknown
function by looking at which genes they are co-expressed with.
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Bram Slabbinck, PhD
Bioinformatics & Systems Biology Division
VIB Department of Plant Systems Biology, UGent
Technologiepark 927, 9052 Gent, BELGIUM
Tel:+32 (0)9 33 13 537
Fax:+32 (0)9 33 13 809
Email: Bram.Slabbinck(a)psb.ugent.be
WWW: http://bioinformatics.psb.ugent.be
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Services and consulting in bioinformatics
http://www.arctix.be
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