Hi all, Just a few points to remember from the ENFIN-DREAM conference (<http://www.enfin.org/page.php?page=enfin_dream>) I attended this week: - ENFIN seems like a very succesful network: partners really share data and collaborate on various projects. If there's a successor to this project, we should try to be part of it. Let's get ourself known to these people, perhaps by inviting some for a seminar? - There will be a DREAM3 conference in Boston end of october/early november 2008. New challenges will also feature model based inference (predicting behavior of unseen data) which is good news for us. The conference will be organized back-to-back with a recomb sysbiol satellite meeting and another meeting organized by Manolis Kellis. - A few talks mentioned "method integration" as we have discussed here as well (to integrate results from enigma and lemone), so this is certainly a topic of interest right now. They used a simple approach of converting all predictions of different methods as p-values which can be combined in weighted sums by the method of <http://www.pnas.org/cgi/content/abstract/102/48/17296>. - Jaak Vilo talked about a method to predict new genes participating in known pathways by overlaying them with expression data (an extension of their tool KEGGanim <http://biit.cs.ut.ee/kegganim/>). They used a completely trivial method (pairwise Pearson correlations with genes in the pathway). I have the feeling it's very easy to improve by modeling the condition dependent expression of genes in a pathway using our tools and then compute the probability for new genes to belong to that pathway. This might be a good project for a new phd student, e.g. focused on combining our arabidopsis expression data with the pathways in reactome. Leuven is also interested in these kind of things. - For Sofie: do you know the BioCreative text mining competitions? <http://www.pdg.cnb.uam.es/BioLINK/BioCreative.eval.html> <http://biocreative.sourcefourge.net> Might be good to participate in the next one to promote genefetch. If you want to know more about specific talks, take a look at the program and ask me. Tom -- Tom Michoel <http://www.psb.ugent.be/~tomic/>