-------- Original Message -------- Subject: DREAM5 Systems Biology Prediction Challenges v2 Date: Wed, 9 Jun 2010 22:12:41 -0400 From: Gustavo Stolovitzky <gustavo@us.ibm.com> To: gustavo@us.ibm.com PLEASE LET ME KNOW IF YOU PREFER NOT TO RECEIVE ANNOUNCEMENTS FROM THE DREAM PROJECT SINCERE APOLOGIES IF YOU RECEIVE THIS ANNOUNCEMENT MORE THAN ONCE *Call for Systems Biology Predictions* *DREAM5: The 5^th DIALOGUE ON REVERSE ENGINEERING ASSESSMENT AND METHODS* Dear Colleague, We would like to you to participate in the following DREAM5 challenges (the first two challenges had been announced earlier) *RELEASED EARLIER: *1. *_Epitope-Antibody Recognition (EAR) Challenge_* <http://wiki.c2b2.columbia.edu/dream/index.php/D5c1>* *- Predict the binding specificity of peptide-antibody interactions. *RELEASED EARLIER:* 2. *_TF-DNA Motif Recognition Challenge_* <http://wiki.c2b2.columbia.edu/dream/index.php/D5c2>* - *Predict the specificity of a Transcription Factor binding to a 35-mer probe. *NEW: *3. *_Systems Genetics Challenge_* <http://wiki.c2b2.columbia.edu/dream/index.php/D5c3>* -* Predict disease phenotypes and infer gene networks from Systems Genetics data *NEW:* 4. *_Network Inference Challenge_* <http://wiki.c2b2.columbia.edu/dream/index.php/D5c4>* -*Infer simulated and in vivo gene regulatory networks from gene expression data We are releasing only one half of Challenge 3. The other half will be posted in our website shortly. To access the data sets, and descriptions of the DREAM5 challenges, please go to _http://wiki.c2b2.columbia.edu/dream/index.php/Challenges_ . The best performers in these challenges will be invited to present in the joint RECOMB Systems Biology/Regulatory Genomics/DREAM5 conference. See _http://recombsat.c2b2.columbia.edu/_ for details on this conference. To learn more about the DREAM project, please go to _http://wiki.c2b2.columbia.edu/dream/index.php/The_DREAM_Project_ *DREAM5 Challenge Submission Timeline* *Late May-Early June, 2010* Call for participation in the challenges. Challenges posted. *September 20, 2010* Predictions Submission Deadline. *Nov 16-20, 2010* RECOMB Systems Biology/Regulatory Genomics/DREAM5 conference. (The DREAM5 conference track is on November 16th.) Sincerely, DREAM5 Challenge Organizers: Gustavo Stolovitzky (chair), IBM Research Robert J Prill, IBM Research Julio Saez Rodriguez, Sys Bio Dept, Harvard University DREAM5 is part of a project we call the DREAM (Dialogue for Reverse Engineering Assessments and Methods) project. Its main objective is to catalyze the interaction between experiment and theory in the area of rigorous assessment of systems biology prediction methods. ===================================== Gustavo Stolovitzky, PhD. Manager, Functional Genomics and Systems Biology IBM Computational Biology Center P.O.Box 218, Yorktown Heights, NY 10598 Office: (914) 945- -- Tom Michoel <http://www.psb.ugent.be/~tomic/>