-------- Original Message -------- Subject: [Fwd: Molecular Systems Biology - New articles published 20 April 2010] Date: Thu, 22 Apr 2010 11:09:29 +0200 From: Kathleen Marchal <kathleen.marchal@biw.kuleuven.be> To: Yves Van De Peer <Yves.vandepeer@psb.ugent.be> check the embo meeting -------- Original Message -------- Subject: Molecular Systems Biology - New articles published 20 April 2010 Date: Tue, 20 Apr 2010 18:39:18 +0200 From: Molecular Systems Biology <Molecular_Systems_Biology@ealert.nature.com> Reply-To: Molecular_Systems_Biology@ealert.nature.com <Molecular_Systems_Biology@ealert.nature.com> To: Kathleen Marchal <Kathleen.Marchal@biw.kuleuven.be> <http://links.ealert.nature.com/ctt?kn=50&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> 20 April 2010 The EMBO Meeting 2010 - advancing the life sciences 4-7 September 2010, Barcelona Featuring: • Plenary lecture sessions devoted to modern evolutionary biology, molecular developmental biology and the rapidly developing field of systems biology • 21 workshops juxtapose classical fields of research with those exploring new frontiers in molecular biology • /Next generation sequencing: technologies & biological insights/ workshop organized by /Molecular Systems Biology/ chief editor Thomas Lemberger • Daily meet the speaker lunches and poster sessions • Popular career development activities For further information, to submit abstracts and to register visit: www.the-embo-meeting.org <http://links.ealert.nature.com/ctt?kn=6&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> *Featured article* Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity <http://links.ealert.nature.com/ctt?kn=2&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> By quantifying metabolite, transcript and enzyme abundances upon local and global perturbations in /Saccharomyces cerevisiae/, we provide evidence that enzyme capacity and metabolite concentrations control metabolic reactions /in vivo/, thereby facilitating flux homeostasis. The observed inverse relationship between substrate metabolite and enzyme concentrations provides a straightforward interpretation for metabolomics data in functional genomics. *Latest articles* *Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity* Sarah-Maria Fendt, Joerg Martin Buescher, Florian Rudroff, Paola Picotti, Nicola Zamboni & Uwe Sauer 13 April 2010 Synopsis <http://links.ealert.nature.com/ctt?kn=44&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Full Text <http://links.ealert.nature.com/ctt?kn=2&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Supplementary info <http://links.ealert.nature.com/ctt?kn=45&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> *Pre-dispositions and epigenetic inheritance in the /Escherichia coli/ lactose operon bistable switch* Lydia Robert, Gregory Paul, Yong Chen, François Taddei, Damien Baigl& Ariel B Lindner 13 April 2010 Synopsis <http://links.ealert.nature.com/ctt?kn=42&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Full Text <http://links.ealert.nature.com/ctt?kn=43&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Supplementary info <http://links.ealert.nature.com/ctt?kn=48&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> *Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression* Luca Mariani, Edda G Schulz, Maria H Lexberg, Caroline Helmstetter, Andreas Radbruch, Max Löhning & Thomas Höfer 13 April 2010 Synopsis <http://links.ealert.nature.com/ctt?kn=49&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Full Text <http://links.ealert.nature.com/ctt?kn=46&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Supplementary info <http://links.ealert.nature.com/ctt?kn=47&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> *Synthesizing a novel genetic sequential logic circuit: a push-on push-off switch* Chunbo Lou, Xili Liu, Ming Ni, Yiqi Huang, Qiushi Huang, Longwen Huang, Lingli Jiang, Dan Lu, Mingcong Wang, Chang Liu, Daizhuo Chen, Chongyi Chen, Xiaoyue Chen, Le Yang, Haisu Ma, Jianguo Chen & Qi Ouyang 09 March 2010 Synopsis <http://links.ealert.nature.com/ctt?kn=30&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Full Text <http://links.ealert.nature.com/ctt?kn=10&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Supplementary info <http://links.ealert.nature.com/ctt?kn=11&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> *Bacterial adaptation through distributed sensing of metabolic fluxes* Oliver Kotte, Judith B Zaugg & Matthias Heinemann 09 March 2010 Synopsis <http://links.ealert.nature.com/ctt?kn=8&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Full Text <http://links.ealert.nature.com/ctt?kn=9&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Supplementary info <http://links.ealert.nature.com/ctt?kn=5&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> *Dynamics within the CD95 death-inducing signaling complex decide life and death of cells* Leo Neumann, Carina Pforr, Joel Beaudouin, Alexander Pappa, Nicolai Fricker, Peter H Krammer, Inna N Lavrik & Roland Eils 09 March 2010 Synopsis <http://links.ealert.nature.com/ctt?kn=7&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Full Text <http://links.ealert.nature.com/ctt?kn=3&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Supplementary info <http://links.ealert.nature.com/ctt?kn=4&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> *GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome* Matthew D Sekedat, David Fenyö, Richard S Rogers, Alan J Tackett, John D Aitchison & Brian T Chait 09 March 2010 Synopsis <http://links.ealert.nature.com/ctt?kn=15&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Full Text <http://links.ealert.nature.com/ctt?kn=14&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Supplementary info <http://links.ealert.nature.com/ctt?kn=25&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> *Zebrafish Pou5f1-dependent transcriptional networks in temporal control of early development* Daria Onichtchouk, Florian Geier, Bozena Polok, Daniel M Messerschmidt, Rebecca Mössner, Björn Wendik, Sungmin Song, Verdon Taylor, Jens Timmer & Wolfgang Driever 09 March 2010 Synopsis <http://links.ealert.nature.com/ctt?kn=20&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Full Text <http://links.ealert.nature.com/ctt?kn=21&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Supplementary info <http://links.ealert.nature.com/ctt?kn=22&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> *Reports* *Target mRNA abundance dilutes microRNA and siRNA activity* Aaron Arvey, Erik Larsson, Chris Sander, Christina S Leslie & Debora S Marks 20 April 2010 Full Text <http://links.ealert.nature.com/ctt?kn=24&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Supplementary info <http://links.ealert.nature.com/ctt?kn=16&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> *Transcript counting in single cells reveals dynamics of rDNA transcription* Rui Zhen Tan & Alexander van Oudenaarden 13 April 2010 Full Text <http://links.ealert.nature.com/ctt?kn=17&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Supplementary info <http://links.ealert.nature.com/ctt?kn=18&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> *A functional metagenomic approach for expanding the synthetic biology toolbox for biomass conversion* Morten OA Sommer, George M Church & Gautam Dantas 13 April 2010 Full Text <http://links.ealert.nature.com/ctt?kn=19&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Supplementary info <http://links.ealert.nature.com/ctt?kn=27&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> *Precision and scaling in morphogen gradient read-out* Aitana Morton de Lachapelle & Sven Bergmann 09 March 2010 Full Text <http://links.ealert.nature.com/ctt?kn=38&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> | Supplementary info <http://links.ealert.nature.com/ctt?kn=39&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> *Editorials* Reconstruction annotation jamborees: a community approach to systems biology <http://links.ealert.nature.com/ctt?kn=33&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> Ines Thiele & Bernhard Ø Palsson 13 April 2010 *Reviews* Strategies for cellular decision-making <http://links.ealert.nature.com/ctt?kn=26&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> Theodore J Perkins & Peter S Swain 17 November 2009 Applications of genome-scale metabolic reconstructions <http://links.ealert.nature.com/ctt?kn=28&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> Matthew A Oberhardt, Bernhard Ø Palsson & Jason A Papin 3 November 2009 *Perspectives* Shifts in growth strategies reflect tradeoffs in cellular economics <http://links.ealert.nature.com/ctt?kn=12&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> Douwe Molenaar, Rogier van Berlo, Dick de Ridder & Bas Teusink 3 November 2009 *Erratum* Inferring condition-specific transcription factor function from DNA binding and gene expression data <http://links.ealert.nature.com/ctt?kn=37&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> Rachel Patton McCord, Michael F Berger, Anthony A Philippakis & Martha L Bulyk 13 April 2010 ADVERTISEMENT <http://links.ealert.nature.com/ctt?kn=41&m=34803880&r=MTc2MzUzMTkxNAS2&b=0&j=NzIzMzU4MTkS1&mt=1&rt=0> You have been sent this Table of Contents Alert because 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Professor in Bioinformatics and Genome Biology Associate Department Director, VIB Department of Plant Systems Biology Group Leader Bioinformatics and Systems Biology Ghent University Technologiepark 927 B-9052 Ghent Belgium Phone: +32 (0)9 331 3807 Cell Phone: +32 (0)476 560 091 Fax: +32 (0)9 331 3809 email: yves.vandepeer@psb.vib-ugent.be http://bioinformatics.psb.ugent.be/