fyi
http://genefriends.org/
GeneFriends is a
functional genomics tool aimed at biologists and clinicians. It is
based on a gene co-expression map that describes which genes tend
to be activated (increase in expression) and deactivated (decrease
in expression) simultaneously in a large number of microarray
datasets. Because the microarray datasets come from a wide range
of conditions, the co-expression map reflects which genes in
general tend to be activated simultaneously and are thus under
similar transcriptional regulation. This information can be used
statistically, using a guilt-by-association approach, to identify
and prioritize novel candidate genes involved in biological
processes and complex diseases for which a seed list of genes
associated with that disease or process is available. It can also
be used to gain insights on genes of unknown function by looking
at which genes they are co-expressed with.
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Bram Slabbinck, PhD
Bioinformatics & Systems Biology Division
VIB Department of Plant Systems Biology, UGent
Technologiepark 927, 9052 Gent, BELGIUM
Tel:+32 (0)9 33 13 537
Fax:+32 (0)9 33 13 809
Email: Bram.Slabbinck@psb.ugent.be
WWW: http://bioinformatics.psb.ugent.be
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Services and consulting in bioinformatics
http://www.arctix.be
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