This one looks quite interesting. Tom -------- Original Message -------- Subject: DREAM4 Predictive Signaling Network Modeling Challenge Added Date: Thu, 2 Jul 2009 20:31:02 -0400 From: Gustavo Stolovitzky <gustavo@us.ibm.com> To: DREAM N-Z <DREAM_N-Z%IBMUS@us.ibm.com> PLEASE LET ME KNOW IF YOU PREFER NOT TO RECEIVE ANNOUNCEMENTS FROM THE DREAM PROJECT SINCERE APOLOGIES IF YOU RECEIVE THIS ANNOUNCEMENT MORE THAN ONCE * **New (and last) Network Inference Challenge Posted: Predictive Signaling Network Modeling Challenge ** DREAM4: The 4^th DIALOGUE ON REVERSE ENGINEERING ASSESSMENT AND METHODS* Dear Colleague, We would like to alert you that the last challenge (Challenge 3) that completes the series of 3 challenges for DREAM4 has just been posted on our website. Please take a look at: http://wiki.c2b2.columbia.edu/dream/index.php/D4c3 for the challenge description. We would like to cordially invite your submissions to this new biological prediction challenge. To access the data sets, and descriptions of the challenges, please go to _http://wiki.c2b2.columbia.edu/dream/index.php/Challenges_ . The best performers in these challenges will be invited to present in the joint RECOMB Systems Biology/Regulatory Genomics/DREAM4 conference. See _http://compbio.mit.edu/recombsat/_ for details on this conference. To learn more about the DREAM4 conference, please go to _http://wiki.c2b2.columbia.edu/dream/index.php/DREAM4conf_ To learn more about the DREAM project, please go to _http://wiki.c2b2.columbia.edu/dream/index.php/The_DREAM_Project_ * Predictive Network Modeling Submission Timeline* * Oct 15, 2009* Predictions Submission Deadline. * Nov 15, 2009* Notifications to Predictors of their Scores and Ranks.* Dec 2-Dec 6, 2009* RECOMB Systems Biology/Regulatory Genomics/DREAM4 conference. (The DREAM4 conference track is on Friday December 4th.) Prediction Submissions must be received in electronic form by 11:59pm (EST) of October 15, 2009. *PLEASE FORWARD THIS NOTICE TO OTHER COLLEAGUES THAT MAY BE INTERESTED IN PARTICIPATING IN THE CHALLENGES*. Sincerely, DREAM4 Conference and Challenge Organizers: Gustavo Stolovitzky (chair), IBM Research Robert J Prill, IBM Research Andrea Califano, Columbia University DREAM4 is part of a project we call the DREAM (Dialogue for Reverse Engineering Assessments and Methods) project. Its main objective is to catalyze the interaction between experiment and theory in the area of cellular network inference. The fundamental question for DREAM is simple: How can researchers assess how well they are describing the networks of interacting molecules that underlie biological systems, and how well can they predict the results of a biological experiment? The answer is not so simple. Researchers have used a variety of algorithms to deduce the structure of very different biological and artificial networks, and evaluated their success using various metrics. What is still needed, and what DREAM aims to achieve, is a fair comparison of the strengths and weaknesses of the methods and a clear sense of the reliability of the network models they produce. -- Tom Michoel <http://www.psb.ugent.be/~tomic/>