October 2012 - Seminars - maillist.psb.ugent.be

Seminar Dr Leah R Band on Monday, November 12 at 11 am
by Delphine Verspeel 30 Oct '12

30 Oct '12

You are receiving this e-mail because you subscribed to our seminars announcements and reminders service at https://maillist.psb.ugent.be/mailman/listinfo/seminars . If you do not wish to receive this information anymore, please unsubscribe from future mailings at https://maillist.psb.ugent.be/mailman/options/seminars . cid:946540515@15122008-0D1CPSBcid:946540515@15122008-0D23 VIB - Department of Plant Systems Biology Technologiepark 927 B - 9052 Gent/Zwijnaarde Phone: +32 9 33 13 800 Fax: +32 9 33 13 809 Http://www.psb.vib-ugent.be

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Seminar Dr Pierre Rouzé
by Delphine Verspeel 29 Oct '12

29 Oct '12

You are receiving this e-mail because you subscribed to our seminars announcements and reminders service at https://maillist.psb.ugent.be/mailman/listinfo/seminars . If you do not wish to receive this information anymore, please unsubscribe from future mailings at https://maillist.psb.ugent.be/mailman/options/seminars . cid:946540515@15122008-0D1CPSBcid:946540515@15122008-0D23 VIB - Department of Plant Systems Biology Technologiepark 927 B - 9052 Gent/Zwijnaarde Phone: +32 9 33 13 800 Fax: +32 9 33 13 809 Http://www.psb.vib-ugent.be

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Upcoming seminars November
by Delphine Verspeel 29 Oct '12

29 Oct '12

Dear All, Enclosed you can find our upcoming seminars for November. Kind regards, Delphine _________________________________________ Delphine Verspeel Administrative Assistant VIB, Department of Plant Systems Biology Ghent University Technologiepark 927 9052 Gent Belgium Phone: +32/9/33.13.800 Fax: +32/9/33.13.809 Http://www.psb.ugent.be despe(a)psb.vib-ugent.be

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PSB event reminder
by contact＠psb.vib-ugent.be 26 Oct '12

26 Oct '12

Calendar Name: seminars Scheduled for: Friday, October 26 2012, 14:00 - 15:30 Event text: Prof Pierre JGM de Wit Laboratory of Phytopathology Wageningen University Wageningen THE NETHERLANDS Details: �The genomes of the related fungal pathogens Cladosporium fulvum and Dothistroma septosporum reveal adaptation to different hosts and lifestyles� ABSTRACT We sequenced and compared the genomes of the Dothideomycete fungal plant pathogens Cladosporium fulvum (Cfu) (syn. Passalora fulva) and Dothistroma septosporum (Dse) that are closely related phylogenetically, but have different lifestyles and hosts. Although both fungi grow extracellularly in close contact with host mesophyll cells, Cfu is a biotroph infecting tomato, while Dse is a hemibiotroph infecting pine. The genomes of these fungi have a similar set of genes (70% of gene content in both genomes are homologs), but differ significantly in size (Cfu >61.1 Mb; Dse 31.2 Mb), which is mainly due to the difference in repeat content (47.2% in Cfu versus 3.2% in Dse). Recent adaptation to different lifestyles and hosts is suggested by diverged sets of genes. Cfu contains an α-tomatinase gene that we predict might be required for detoxification of tomatine, whilst this gene is absent in Dse. Many genes encoding secreted proteins are unique to each species and the repeat-rich areas in Cfu are enriched for these species-specific genes. In contrast, conserved genes suggest common host ancestry. Homologs of Cfu effector genes, including Ecp2 and Avr4, are present in Dse and induce a Cf-Ecp2- and Cf-4-mediated hypersensitive response, respectively. Strikingly, genes involved in production of the toxin dothistromin, a likely virulence factor for Dse, are conserved in Cfu, but their expression differs markedly with essentially no expression by Cfu in planta. Likewise, Cfu has a carbohydrate-degrading enzyme catalog that is more similar to that of necrotrophs or hemibiotrophs and a larger pectinolytic gene arsenal than Dse, but many of these genes are not expressed in planta or are pseudogenized. Overall, comparison of their genomes suggests that these closely related plant pathogens had a common ancestral host but since adapted to different hosts and lifestyles by a combination of differentiated gene content, pseudogenization and gene regulation.

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PSB event reminder
by contact＠psb.vib-ugent.be 24 Oct '12

24 Oct '12

Calendar Name: seminars Scheduled for: Friday, October 26 2012, 14:00 - 15:30 Event text: Prof Pierre JGM de Wit Laboratory of Phytopathology Wageningen University Wageningen THE NETHERLANDS Details: �The genomes of the related fungal pathogens Cladosporium fulvum and Dothistroma septosporum reveal adaptation to different hosts and lifestyles� ABSTRACT We sequenced and compared the genomes of the Dothideomycete fungal plant pathogens Cladosporium fulvum (Cfu) (syn. Passalora fulva) and Dothistroma septosporum (Dse) that are closely related phylogenetically, but have different lifestyles and hosts. Although both fungi grow extracellularly in close contact with host mesophyll cells, Cfu is a biotroph infecting tomato, while Dse is a hemibiotroph infecting pine. The genomes of these fungi have a similar set of genes (70% of gene content in both genomes are homologs), but differ significantly in size (Cfu >61.1 Mb; Dse 31.2 Mb), which is mainly due to the difference in repeat content (47.2% in Cfu versus 3.2% in Dse). Recent adaptation to different lifestyles and hosts is suggested by diverged sets of genes. Cfu contains an α-tomatinase gene that we predict might be required for detoxification of tomatine, whilst this gene is absent in Dse. Many genes encoding secreted proteins are unique to each species and the repeat-rich areas in Cfu are enriched for these species-specific genes. In contrast, conserved genes suggest common host ancestry. Homologs of Cfu effector genes, including Ecp2 and Avr4, are present in Dse and induce a Cf-Ecp2- and Cf-4-mediated hypersensitive response, respectively. Strikingly, genes involved in production of the toxin dothistromin, a likely virulence factor for Dse, are conserved in Cfu, but their expression differs markedly with essentially no expression by Cfu in planta. Likewise, Cfu has a carbohydrate-degrading enzyme catalog that is more similar to that of necrotrophs or hemibiotrophs and a larger pectinolytic gene arsenal than Dse, but many of these genes are not expressed in planta or are pseudogenized. Overall, comparison of their genomes suggests that these closely related plant pathogens had a common ancestral host but since adapted to different hosts and lifestyles by a combination of differentiated gene content, pseudogenization and gene regulation.

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PSB event reminder
by contact＠psb.vib-ugent.be 19 Oct '12

19 Oct '12

Calendar Name: seminars Scheduled for: Friday, October 19 2012, 14:00 - 15:30 Event text: Prof Frank Van Breusegem VIB, Dept. of Plant Systems Biology Ghent University Gent BELGIUM Details: �Oxidative Stress Signal Transduction� ABSTRACT Different biotic and abiotic stresses adversely affect plant growth and development. A common theme within these environmental factors is the perturbation of reactive oxygen species (ROS) homeostasis. The signal transduction mechanisms of the oxidative stress response in plants are poorly understood. W e conducted genetic and chemical screens, which combined with proteomic approaches will lead to a more comprehensive overview on the components of the network that govern the oxidative stress response. These efforts resulted in the identification of a number of genes as new members of the oxidative stress gene network in plants. In our recent studies, we have identified a novel transcriptional regulator of the mitochondrial retrograde regulation and are assessing the modulation of cellular NAD(P) homeostasis through the perturbation of sirtuins as a new strategy to improve plant performance in stress conditions.

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Seminar Prof Pierre JGM de Wit on Friday, October 26 at 2pm
by Delphine Verspeel 18 Oct '12

18 Oct '12

You are receiving this e-mail because you subscribed to our seminars announcements and reminders service at https://maillist.psb.ugent.be/mailman/listinfo/seminars . MY APOLOGIES FOR MULTIPLE POSTINGS If you do not wish to receive this information anymore, please unsubscribe from future mailings at https://maillist.psb.ugent.be/mailman/options/seminars . cid:946540515@15122008-0D1CPSBcid:946540515@15122008-0D23 VIB - Department of Plant Systems Biology Technologiepark 927 B - 9052 Gent/Zwijnaarde Phone: +32 9 33 13 800 Fax: +32 9 33 13 809 Http://www.psb.vib-ugent.be

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PSB event reminder
by contact＠psb.vib-ugent.be 12 Oct '12

12 Oct '12

Calendar Name: seminars Scheduled for: Friday, October 12 2012, 14:00 - 15:30 Event text: Dr Arp Schnittger Department of Molecular Mechanisms of Phenotypic Plasticity Institut de Biologie Mol�culaire des Plantes du CNRS Universit� de Strasbourg Strasbourg FRANCE Details: �How to make stable decisions in cell proliferation and differentiation� ABSTRACT The decision to replicate its DNA is of crucial importance for every cell and in many organisms decisive to progress through the entire cell cycle. Using pollen as a model system, we have identified a general regulatory cascade controlling entry into S phase in many if not all Arabidopsis cells. This cascade comprises the Arabidopsis homologs of the animal transcription factor E2F, the plant homolog of the animal transcriptional repressor Retinoblastoma (Rb)-related 1 (RBR1), the plant-specific F-box protein, F-BOX-LIKE 17, the plant specific cyclin-dependent kinase (CDK) inhibitors KRPs, as well as CDKA;1, the plant homolog of the yeast and animal Cdc2+/Cdk1 kinases. Biomathematical simulations and subsequent experimental confirmation of computational predictions revealed that this regulatory circuit can give rise to hysteresis highlighting the identified dosage sensitivity of CDK inhibitors in this network. Remarkably, many components of this cell cycle control module appear to function in the control of asymmetric division and cell fate specification as well. I will present data from our team showing that RBR1 not only controls cell proliferation but also cell differentiation genes during root meristem and stomata development. This leads to a CDKA;1-dose dependent model of formative divisions in which low and medium levels of CDKA;1 are sufficient for symmetric divisions but high kinase levels being required for asymmetric divisions. An important aspect of this wiring is again the hysteretic behavior of the system revealing an intimate connection between cell cycle progression and cell fate acquisition.

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Seminar Prof Frank Van Breusegem
by Delphine Verspeel 11 Oct '12

11 Oct '12

You are receiving this e-mail because you subscribed to our seminars announcements and reminders service at <https://maillist.psb.ugent.be/mailman/listinfo/seminars> https://maillist.psb.ugent.be/mailman/listinfo/seminars. If you do not wish to receive this information anymore, please unsubscribe from future mailings at <https://maillist.psb.ugent.be/mailman/options/seminars> https://maillist.psb.ugent.be/mailman/options/seminars. cid:946540515@15122008-0D1C PSB cid:946540515@15122008-0D23 VIB - Department of Plant Systems Biology Technologiepark 927 B - 9052 Gent/Zwijnaarde Phone: +32 9 33 13 800 Fax: +32 9 33 13 809 Http://www.psb.vib-ugent.be

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PSB event reminder
by contact＠psb.vib-ugent.be 10 Oct '12

10 Oct '12

Calendar Name: seminars Scheduled for: Friday, October 12 2012, 14:00 - 15:30 Event text: Dr Arp Schnittger Department of Molecular Mechanisms of Phenotypic Plasticity Institut de Biologie Mol�culaire des Plantes du CNRS Universit� de Strasbourg Strasbourg FRANCE Details: �How to make stable decisions in cell proliferation and differentiation� ABSTRACT The decision to replicate its DNA is of crucial importance for every cell and in many organisms decisive to progress through the entire cell cycle. Using pollen as a model system, we have identified a general regulatory cascade controlling entry into S phase in many if not all Arabidopsis cells. This cascade comprises the Arabidopsis homologs of the animal transcription factor E2F, the plant homolog of the animal transcriptional repressor Retinoblastoma (Rb)-related 1 (RBR1), the plant-specific F-box protein, F-BOX-LIKE 17, the plant specific cyclin-dependent kinase (CDK) inhibitors KRPs, as well as CDKA;1, the plant homolog of the yeast and animal Cdc2+/Cdk1 kinases. Biomathematical simulations and subsequent experimental confirmation of computational predictions revealed that this regulatory circuit can give rise to hysteresis highlighting the identified dosage sensitivity of CDK inhibitors in this network. Remarkably, many components of this cell cycle control module appear to function in the control of asymmetric division and cell fate specification as well. I will present data from our team showing that RBR1 not only controls cell proliferation but also cell differentiation genes during root meristem and stomata development. This leads to a CDKA;1-dose dependent model of formative divisions in which low and medium levels of CDKA;1 are sufficient for symmetric divisions but high kinase levels being required for asymmetric divisions. An important aspect of this wiring is again the hysteretic behavior of the system revealing an intimate connection between cell cycle progression and cell fate acquisition.

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