Calendar Name: seminars
Scheduled for: Friday, March 2 2012, 14:00 - 15:30
Event text: Prof Takashi Hashimoto
Graduate School of Biological Sciences
Nara Institute of Science and Technology
Takayama-cho
Ikoma
JAPAN
Details: �Organization of cortical microtubule arrays in
Arabidopsis�
ABSTRACT
Microtubules are nucleated from dispersed cortical
regions in interphase plant cells, where the majority of
nucleation events occur from the
-tubulin-containing sites on the pre-existing
microtubules as branching patterns. The minus-ends of
newly formed daughter microtubules are usually released
from sites of nucleation by the action of the
microtubule severing complex katanin, and the free
microtubules are then transported on the cortex by
polymer treadmilling. Subsequent
microtubule-microtubule interactions promote microtubule
bundling and ordering, which establishes particular
patterns of interphase cortical arrays. With special
interests in helical microtubule arrays, we have been
studying possible mechanisms and particular molecules
that underlie organization of cortical microtubule
arrays.
M. Nakamura, D. Ehrhardt, and T. Hashimoto (2010)
Microtubule and katanin dependent dynamics of
microtubule nucleation complexes in the Arabidopsis
cortical array. Nature Cell Biol. 12: 1064-1070.
M. Nakamura, and T. Hashimoto (2009) A mutation in the
Arabidopsis -tubulin-containing complex subunit
causes helical growth and abnormal microtubule
branching. J. Cell Sci. 122: 2208-2217.
T. Ishida, Y. Kaneko, M. Iwano, and T. Hashimoto (2007)
Helical microtubule arrays in a collection of twisting
tubulin mutants of Arabiodpsis thaliana. Proc. Natl.
Acad. Sci. USA 104: 8544-8549.
