You are receiving this e-mail because you subscribed to our seminars announcements and reminders service at [ https://maillist.psb.ugent.be/mailman/listinfo/seminars | https://maillist.psb.ugent.be/mailman/listinfo/seminars ] . '' Multiple functions of the plant unique ESCRT component FREE1 in Arabidopsis thaliana '' Prof Liwen Jiang Shool of Life Sciences Centre for Cell & Developmental Biology and State Key Laboratory of Agrobiotechnology The Chinese University of Hong Kong (CUHK) CHINA Thursday, June 23, 2022 14:00 The plant endomembrane system contains several functionally distinct membrane-enclosed organelles, including the endoplasmic reticulum (ER), Golgi apparatus, trans-Golgi network (TGN) or early endosomes (EE), prevacuolar compartment (PVC) or multivesicular body (MVB) and vacuole. The endosomal sorting complex required for transport (ESCRT) machinery mediates the formation of intraluminal vesicles (ILVs) in MVBs as well as the sorting of the ubiquitinated cargoes into the internal vesicles (ILVs) in eukaryotes. Since 2014, we have characterized a plant unique ESCRT component termed FYVE domain protein required for endosomal sorting 1 (FREE1) and demonstrated that FEFF1 plays multiple functions with distinct underlying mechanisms in plants, including regulation of MVB and vacuole biogenesis (Current Biology 2014), crosstalk of the endomembrane system with the autophagic pathway (PNAS 2015), Abscisic Acid (ABA) signaling (Nature Plants 2019), degradation of lipid droplets (LDs) in germinating seedlings (Plant Cell 2022), and autophagosome closure under stress condition (NC 2022R). We have also identified and characterized several Arabidopsis sof (suppressor of free1) as novel regulators of the MVB pathway (NC 2018; Plant Cell 2019; TBD 2022). In this talk, I will summarize our major findings and present an update on our research progress of multi-functions of FREE1 in Arabidopsis. Supported by Research Grants Council of Hong Kong and CUHK. Jozef Schell seminar room Technologiepark 71 - 9052 Invited by Prof Dirk Inzé and Prof Daniël Van Damme If you do not wish to receive this information anymore, please unsubscribe from future mailings at [ https://maillist.psb.ugent.be/mailman/listinfo/seminars | https://maillist.psb.ugent.be/mailman/listinfo/seminars ] Genome editing, cutting-edge technology for a sustainable agriculture VIB-UGent Center for Plant Systems Biology Ghent University Technologiepark-Zwijnaarde 71 9052 Ghent-Belgium Phone: +32(0)9 331 38 00 [ http://www.psb.vib-ugent.be/ | https://www.psb.ugent.be/ ]
