You are receiving this e-mail because you subscribed to our seminars announcements and reminders service at [ https://maillist.psb.ugent.be/mailman/listinfo/seminars | https://maillist.psb.ugent.be/mailman/listinfo/seminars ] . '' The central function of the thiol redox regulatory network in plant-environment interaction '' Prof Karl-Josef Dietz Biochemistry and Physiology of Plants Bielefeld University GERMANY Thursday, November 30, 2023 11:00 All cells express a thiol protein-metabolite network consisting of redox input elements, redox transmitters, redox sensors and redox target proteins. Electron input into the network from NADPH or ferredoxin and electron drainage by reactive molecular species adjusts the redox state of the target proteins that alter or even switch function. The antagonism between thiol oxidation and reduction enables efficient control of virtually all cellular processes including metabolism, transcription and translation. The best-studied mechanism is the dithiol-disulfide transition in the Calvin Benson Cycle in photosynthesis, including mixed disulfide formation by glutathionylation. However, the adjustment of the proper thiol redox state is a fundamental property of all cellular compartments. The talk will elaborate on the multiple functions of thiol peroxidases, in particular peroxiredoxins, as redox sensors and regulators. It will be shown that reconstituting the system in vitro - in this case of the cytosol - provides important mechanistic insight that is hardly achievable in genetic approaches. In the end, a dual system comprising stress-specific sensors and a general quantitative stress sensory system is proposed to enable the plant to optimize its response. The quantitative stress sensory system exploits the redox and reactive oxygen species (ROS) network by altering the oxidation and reduction rates of individual redox-active molecules under stress impact. The proposed mechanism of quantitative stress sensing also fits the requirement of dealing with multifactorial stress conditions. Jozef Schell seminar room Technologiepark 71 - 9052 Invited by Prof Dirk Inzé and Prof Frank Van Breusegem If you do not wish to receive this information anymore, please unsubscribe from future mailings at [ https://maillist.psb.ugent.be/mailman/listinfo/seminars | https://maillist.psb.ugent.be/mailman/listinfo/seminars ] Genome editing, cutting-edge technology for a sustainable agriculture VIB-UGent Center for Plant Systems Biology Ghent University Technologiepark-Zwijnaarde 71 9052 Ghent-Belgium Phone: +32(0)9 331 38 00 [ http://www.psb.vib-ugent.be/ | https://www.psb.ugent.be/ ]
