''Auxin dynamics during developmental programmed cell death events in the Arabidopsis root''
M. SHTIN 1,2, D. SCINTU 1,2, N. SVOLACCHIA 1,2, P. COSTANTINO 2, S. SABATINI 2, R. DELLO IOIO 2, RICCARDO DI MAMBRO 1
1 Department of Biology, University of Pisa, Pisa, Italy
2 Department of Biology and Biotechnology “Charles Darwin”, University Sapienza, Rome, Italy
Programmed Cell Death (PCD) represents a key process for directing organ development. In Arabidopsis, characteristic PCD events are crucial for the correct development of the lateral root cap, the most external tissue of the root. The lateral root cap translates the environmental stimuli into internal cellular response, thus leading to the regulation of the growth and architecture of the entire organ. In order to ensure tissue proper development and functions, the uppermost cells of this tissue undergoes a characteristic PCD event. Recent evidences hinted on a correlation between the activity of the hormone auxin and PCD events, including those occurring in the lateral root cap. Exploiting a live imaging approach combined with cell type specific gene editing, we show that auxin transport dynamics govern the timing of the uppermost lateral root cap cells PCD occurrence. We thus suggest the existence of a specific molecular circuit that confers positional cues to lateral root cap cells to coordinate cellular turnover and whole organ development.
Invited by Prof Dirk Inzé and Prof Tom Beeckman
Genome editing, cutting-edge technology for a sustainable agriculture