From: "seminar" <seminar@psb.vib-ugent.be>
To: "meetings" <meetings@psb.vib-ugent.be>
Sent: Thursday, June 12, 2025 8:05:01 AM
Subject: PSB Seminar TODAY@11:00H : Glutathione metabolism and its implications for growth

| PSB Seminar TODAY@11:00H : Glutathione metabolism and its implications for growth Andreas Meyer Universität Bonn Germany Where: Jozef Shell Seminar room - VIB-UGent Center for Plant Systems Biology Ghent University Technologiepark 71 - 9052 Ghent - Belgium Tel. +32(0)9 331 38 00 www.psb.ugent.be When: 12-JUN-2025@11:00 Invited by Yves Van de Peer , Frank Van Breusegem Glutathione was among the first metabolites cells invented for defence against the destructive power of reactive oxygen when the oxygen concentration on Earth started to rise during the great oxygenation event approximately 2.4 billion years ago. In addition to detoxifying reactive oxygen species, glutathione now has a wide range of other functions, including redox control and redox signalling, detoxifying electrophilic compounds, acting as a cofactor in metabolic reactions and donating sulfur donor for synthesising sulfur-containing metabolites. The developmental arrest observed in glutathione-deficient Arabidopsis mutants suggests a potential connection between glutathione and meristematic activity. However, our understanding of the impact of glutathione metabolism on growth remains limited. In order to understand redox signalling mechanisms, the dynamics of the respective redox changes must be understood in terms of both time and space. Over the past two decades, the use of genetically encoded probes for H2O2 and the glutathione redox potential (EGSH) has provided access to the respective physiological parameters in live cells. In combination with genetic approaches, they allow the genetic dissection of production and transmission systems in vivo. The talk will address various glutathione-dependent processes, focussing particularly on those mediated by glutaredoxins, and will discuss our current understanding of how glutathione affects growth in Arabidopsis. Jozef Shell Seminar room - VIB-UGent Center for Plant Systems Biology Ghent University Technologiepark 71 - 9052 Ghent - Belgium Tel. +32(0)9 331 38 00 www.psb.ugent.be If you do not wish to receive this information anymore, please unsubscribe from future mailings at https://maillist.psb.ugent.be/mailman/listinfo/seminars